Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome. by Prabhakar Rajan, Caroline Dalgliesh, Phillippa J Carling, Thomas Buist, Chaolin Zhang, Sushma N Grellscheid, Kelly Armstrong, Jacqueline Stockley, Cedric Simillion, Luke Gaughan, Gabriela Kalna, Michael Q Zhang, Craig N Robson, Hing Y Leung, David J Elliott

“…We also identified 1279 putative androgen-regulated alternative events, of which 325 (∼25%) mapped to known alternative splicing events or alternative first/last exons. We selected 30 androgen-dependent alternative events for RT-PCR validation, including mRNAs derived from genes encoding tumour suppressors and cell cycle regulators. …”
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Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis by Bin Qi, Hai-Yan Wang, Xiao Ma, Yu-Feng Chi, Chun Gui

“…Methods Five DCM-related microarray datasets were downloaded from the Gene Expression Omnibus (GEO). …”
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Investigational Management for a Positive NIPT Result - Case Report by Elena Evelina STOICA, Laurentiu Camil BOHILTEA, Delia-Maria Gradinaru-FOMETESCU, Monica Mihaela CIRSTOIU

“…Following genetic consultation, further investigations were conducted to stratify the fetal risk of inheriting the microdeletion syndrome. As a result, microarray CGH cytoarray from amniotic fluid was performed, and no 22q11.2 deletion was detected. …”
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Integrated bioinformatic analysis of the shared molecular mechanisms between ANCA-associated vasculitis and atherosclerosis by Xun Hu, Inmaculada Xu Lou, Qilan Chen

“…The CytoHubba plugin and HG validation demonstrated the reliability of the selected five HGs. Co-expression network analysis revealed that these five HGs could influence monocyte migration. …”
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Comparison of monocyte gene expression among patients with neurocysticercosis-associated epilepsy, Idiopathic Epilepsy and idiopathic headaches in India. by Vasudevan Prabhakaran, Douglas A Drevets, Govindan Ramajayam, Josephine J Manoj, Michael P Anderson, Jay S Hanas, Vedantam Rajshekhar, Anna Oommen, Hélène Carabin

“…Fifteen genes up-regulated in NCC patients compared with other groups were selected based on possible relevance to NCC, and analyzed by qPCR in all patients' samples. …”
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Interferon-stimulated circHOMER1 attenuates antiviral innate immunity by Ao Zhang, Ranran Yao, Shijin Geng, Haiying Wang, Rong-Chun Tang, Hengxiang Yu, Rui Xu, Hong-Yan Chen, Yunxuan Zhou, Lan Zhang, Jun Zhang

“…Furthermore, circHOMER1 was found to disrupt the interaction between Ras GTPase-activating protein-binding protein 1 (G3BP1) and retinoic-acid-inducible protein I (RIG-I), impairing the detection of viral RNAs by RIG-I. Notably, the concordant immunosuppressive effects of circHOMER1 were observed in mouse infection models. …”
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A comprehensive review of diagnostic approaches for hepatitis D by Wen-Hui Liu, Wen-Hui Liu, Jia-Yue Cui, Miao Yu, Xiao-Dong Shi, Yi-Lin Che, Chu-Yan Wang, Xiu-Mei Chi

“…Established techniques like chemiluminescence immunoassay, quantitative microarray antibody capture, and lateral flow assays are being improved. …”
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Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis by LEI Lei, LYU Yuxin, ZHANG Jing

“…The expression of TNFAIP6 in human RA fibroblast-like synovial cell line MH7A was detected by RT-qPCR and Western blotting under simulated inflammatory environment. …”
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Prenatal diagnosis of imprinted associated chromosome abnormalities identified by noninvasive prenatal testing (NIPT) by Haishan Peng, Dongmei Wang, Fangfang Guo, Yaping Hou, Tingting Hu, Qianyi Du, Jiexia Yang

“…Abstract To explore the clinical value of noninvasive prenatal testing (NIPT) combined with chromosomal microarray analysis (CMA)/copy number variation sequencing (CNV-seq), methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA), and fluorescence in situ hybridization (FISH) in the early screening of imprinted chromosome abnormalities. …”
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Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor. by Ester Rozenblum, Jose R Sotelo-Silveira, Gina Y Kim, Jack Y Zhu, Christopher C Lau, Nicole McNeil, Susana Korolevich, Hongling Liao, James M Cherry, David J Munroe, Thomas Ried, Paul S Meltzer, Walter M Kuehl, Anna V Roschke

“…A number of single nucleotide variations (SNVs)/mutations were detected in OVDM1 and the metastatic tumor samples. …”
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Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome by Karol Charkiewicz, Monika Zbucka-Kretowska, Joanna Goscik, Slawomir Wolczynski, Adam Lemancewicz, Piotr Laudanski

“…To assess the expression of autoantibodies in the blood plasma, we used a protein microarray, which allows for simultaneous determination of 9000 proteins per sample. …”
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Human umbilical vein endothelial cell miRNA secretome highlights endothelial origin of serum miRNAs by Nora J. Doleschall, Zoltán F. Doleschall, Flóra Demeter, Márta L. Debreczeni, Erika Kajdácsi, László Cervenak, Katalin Keltai

“…Our results also demonstrate that the microarray technology has great use in precision microRNA biomarker discovery using simple models, which should be utilised for further mapping of cell-type specific healthy signatures to further refine blood-based diagnostics.…”
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Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs. by Owen H Donohoe, Kathy Henshilwood, Keith Way, Roya Hakimjavadi, David M Stone, Dermot Walls

“…MiRNAs from the two confirmed pre-miRNAs were also detected in gill tissue from CyHV-3-infected carp. …”
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The impact of MITF expression on tumor-infiltrating lymphocytes in melanoma: Insights into immune microenvironment dynamics by Damir Vučinić, Matea Lekić, Gordana Žauhar, Gordana Zamolo

“…Archival formalin-fixed, paraffin-embedded tissue samples from 81 primary melanoma patients were analyzed via tissue microarray immunohistochemistry to assess MITF protein levels. …”
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Effects of hsa-mir-145-5p on the Regulation of msln Expression in Colorectal Adenocarcinoma by Junhua Li, null Bulin Baila, Tian Xiang Xu, Jiang Song, null Su Rina, Ji Wu, Tegexibaiyin Wang

“…In recent years, research data show that some miRNAs are differentially expressed in cancer tissues, and their expression is closely contributed with the prognosis of CRC. Microarray technology was used, and 179 miRNAs were screened out with significantly altered expression in CRC tissues compared with adjacent tissues. …”
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Association of lipoprotein(a) and LPA gene with calcific aortic valve disease by Xinyi Yu, Zean Fu, Minghuan Yu, Yibo Shi

“…Meta-analysis was performed using RevMan and Stata. AVC-related gene microarray data were obtained from the GEO database. …”
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Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules. by Xiaolin Xiao, Aida Moreno-Moral, Maxime Rotival, Leonardo Bottolo, Enrico Petretto

“…We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. …”
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The Novel Action of miR-193b-3p/CDK1 Signaling in HCC Proliferation and Migration: A Study Based on Bioinformatic Analysis and Experimental Investigation by Xue Pang, Wei Wan, Xingxing Wu, Yu Shen

“…A growing number of novel targets underlying HCC pathophysiology have been detected using microarray high throughput screening platforms. …”
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Thyroid hormone signalling genes are regulated by photoperiod in the hypothalamus of F344 rats. by Alexander W Ross, Gisela Helfer, Laura Russell, Veerle M Darras, Peter J Morgan

“…Surprisingly, large changes in hypothalamic thyroid hormone levels or TRH expression were not detected. Expression of NPY and GALP, two genes known to regulate GHRH, were also changed by photoperiod. …”
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The Construction of ceRNA Regulatory Network Unraveled Prognostic Biomarkers and Repositioned Drug Candidates for the Management of Pancreatic Ductal Adenocarcinoma by Busra Aydin, Keziban Okutan, Ozge Onluturk Aydogan, Raghu Sinha, Beste Turanli

“…The mRNA, miRNA, and circRNA expression profiles of PDAC were obtained from nine microarray datasets. Differentially expressed genes (DEGs), microRNAs (DEmiRNAs), and circular RNAs (DEcircRNAs) were identified. …”
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