Barcoded Hybrids of Extracellular Vesicles and Lipid Nanoparticles for Multiplexed Analysis of Tissue Distribution by Alena Ivanova, Renata Chalupska, Ana Filipa Louro, Mike Firth, Hernán González‐King Garibotti, Leif Hultin, Franziska Kohl, Elisa Lázaro‐Ibáñez, Julia Lindgren, Gentian Musa, Erik Oude Blenke, Andreia M. Silva, Louis Szeponik, Agnes Taylor, Ida Viken, Xiaoqin Wang, Karin Jennbacken, John Wiseman, Niek Dekker

“…To examine this possibility further, it is shown that HAP1 hEV loaded with Cre mRNA displayed functional delivery to the lungs. Overall, the barcoded hEV technology enables rapid profiling of biodistribution across EV cell sources, which is poised to improve throughput and extent of EV studies, while reducing the number of animals required for research.…”
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Presenting a Quantum Leadership Model to Establish Organizational Civilization in the Iranian Higher Education System by reza heydari, hamidreza rezaeekelidbari, musa chaman zamin

“…The results of this study showed that by implementing the model obtained in this study, we can witness positive consequences in terms of implementing quantum leadership in order to establish organizational civilization in the country's higher education Extended abstract Introduction Creating new knowledge has long been one of the main functions of universities, and the greatest effort of the academic community is to promote knowledge and strengthen intellectual capital by utilizing existing informational, intellectual, and human resources; therefore, universities must identify, extract, and utilize these resources using new and appropriate leadership and management methods. …”
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Safety and efficacy of 3D navigation-guided endoscopy for intracranial hemorrhage in patients with early cerebral hernia by Jun Zhang, Sitong Zhou, Taihui Zhang, Yongsheng Chen, Haikang Zhao, Hongyu Cheng, Peng Wang, Zhuhui Li, Jiajing Chen, Wobin Huang, Bocong Liu, Dayu Li, Hanwen Zhao, Xinwei Liu, Wenqiang Gao, Lijin Huang, Yuqian Li

“…Methods: We conducted a retrospective analysis of 11 ICH patients with cerebral hernia who underwent neuroendoscopic hematoma evacuation guided by 3D navigation technology at the Department of Neurosurgery in Dalang Hospital between January 2019 and January 2022. By utilizing 3D reconstructed CT scanning technology, our research team successfully created patient-specific brain and hematoma models. …”
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Beyond access: assessing WASH service delivery models in healthcare facilities of North Mecha, Dera, and Farta, Ethiopia by Abireham Misganaw Ayalew

“…The service providers (HCFs), however, are neither aware of them nor fully comprehend them. Common water sources for healthcare facilities (HCFs) included shallow wells equipped with solar power and utility connections. …”
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A High-Throughput Microphysiological Liver Chip System to Model Drug-Induced Liver Injury Using Human Liver Organoids by Sophia R. Meyer, Charles J. Zhang, Max A. Garcia, Megan C. Procario, Sanghee Yoo, Amber L. Jolly, Sumin Kim, Jiho Kim, Kyusuk Baek, Roland D. Kersten, Robert J. Fontana, Jonathan Z. Sexton

“…Results: The Curiochips successfully maintained liver physiology and function, showing strong albumin secretion and cytochrome (CYP) P450 activities for 28 days. …”
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Comparison of the efficacy of one-stage revision surgery guided by precise pathogen diagnosis and conventional two-stage revision for chronic knee periprosthetic joint infection by Zhengwei Xiao, Jinyuan Zeng, Zeyu Zhang, Baijian Wu, Zihao Hong, Yufeng Guo, Chengguo Huang, Zida Huang, Zhaoyang Wu, Wenming Zhang, Xinyu Fang, Wenbo Li

“…The baseline clinical characteristics did not significantly differ between the two groups. Utilizing our optimized pathogen detection protocol, successful pathogen identification was achieved in all cases across both groups. …”
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An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment by Enzo Romero, Jose G. Garcia, Magno Parra, Sebastian Caballa, Alejandro M. Saldarriaga, Edson F. Luque, Dante J. Rodriguez, Victoria E. Abarca, Dante A. Elias

“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
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OpDetect: A convolutional and recurrent neural network classifier for precise and sensitive operon detection from RNA-seq data. by Rezvan Karaji, Lourdes Peña-Castillo

“…Here, we introduce a general method, OpDetect, that directly utilizes RNA-sequencing (RNA-seq) reads as a signal over nucleotide bases in the genome. …”
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A novel unified variational finite difference (VFD) solution method for optimal control problems by Amir Norouzzadeh, Nader Nariman-zadeh, Reza Ansari

“…To do so, the general form of quadratic performance index function and nonlinear state equations are considered first. …”
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Respiratory Syncytial Virus Infection Modeled in Aging Cotton Rats (Sigmodon hispidus) and Mice (Mus musculus) by Olivia E. Harder, Stefan Niewiesk

“…In mice and cotton rats, treatment with ibuprofen, a nonselective nonsteroidal anti-inflammatory drug (NSAID), to decrease the chronic low-grade inflammation of the elderly immune system has proven successful in restoring the function of cytotoxic lymphocytes. …”
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Identifying and Mapping Challenges of Industrial-to-Aviation Transformation Through Aczel–Alsina and Grey DEMATEL-ISM Analysis by Chih-Wei Chien, Jiann-Haw Liou, Sun-Weng Huang

“…Our approach employed grey numbers to address individual uncertainty and utilized the Aczel–Alsina function to integrate expert opinions while accounting for inter-expert disagreements. …”
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Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China by Jin Zheng, Yusheng Lu, Peizhi Xu, Kaizhi Xie, Changmin Zhou, Yaying Li, Haoyang Geng, Qianyuan Wang, Wenjie Gu

“…Paddy fields are the main agricultural source of greenhouse gas methane (CH₄) emissions. …”
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Chitosan nanocarriers: Pioneering encapsulation and targeted delivery of 5-fluorouracil - A comprehensive review by Mariyeh Rajaei, Hamid Rashedi, Fatemeh Yazdian, Mehrab Pourmadadi, Abbas Rahdar, Sadanand Pandey

“…So far, a number of nano systems have been developed for encapsulation and targeted delivery of 5FU to improve its solubility, bioavailability, and functional characteristics, leading to the development of, for example, 5FU carriers in topical treatments. …”
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Evaluating the use of eggshell powder and sawdust ash as cement replacements in sustainable concrete development by Ajoy Kumer, Md. Arif Arman Akash, Pritom Dey, Faysal Montasir, Kaysarul Islam Bhuiyan, Farhan Fahad

“…Concrete, the most widely utilized material in construction worldwide, contributes significantly tothe consumption of natural resources and energy. …”
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Toward a sustained recovery of the lodging sector: a management path to lessen the Corona Variants upshots by Ola Abdel Moneim Emara, Hazem Tawfik Halim, Mohamed Samy El-Deeb, Yasser Tawfik Halim

“…The paper’s scientific value is that it functionalizes a broad inductive method of qualitative research in which a merge of the interpretation of management enabling factors and health enabling trends in the lodging sector and luxury hotel managers’ responses obtained through exploratory qualitative research is utilized to cluster the managers’ responses and thus generalize the information in the setting of a Framework for Health Crisis Management in the lodging sector. …”
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Digital twin brain simulator for real-time consciousness monitoring and virtual intervention using primate electrocorticogram data by Yuta Takahashi, Hayato Idei, Misako Komatsu, Jun Tani, Hiroaki Tomita, Yuichi Yamashita

“…This self-organization facilitated simulation of virtual drug administration and uncovered functional networks underlying changes in brain function during anesthesia. …”
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Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach by Wen-Di Wang, Xin-Yi Fan, Xiao-Qi Wei, Wang-Jing Chai, Fang-He Li, Kuo Gao, Bin Liu, Bin Liu, Shu-Zhen Guo

“…The Chou-Talalay and Zero Interaction Potency (ZIP) models were utilized to quantify the synergistic relationships. …”
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Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…In vitro experiments were conducted with the primary objective of appraising both the expression profile and the precise functional attributes of SMAD3 within the milieu of Liver Hepatocellular Carcinoma (LIHC). …”
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Designing accessible and independent living spaces for visually impaired individuals: a barrier-free approach to interior design by Anushka Patil, Smruti Raghani

“…Adaptive design offers solutions that utilize sensory input, spatial predictability, and barrier-free layouts to address these challenges. …”
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أثر الدين في التوجهات الجيوبوليتيكية للولايات المتحدة الأمريكية تجاه إسرائيل by عيسى السيد عيسى دسوقي, حسن قطب حسن قطب

“…It is grounded in a theoretical framework that integrates political realism and constructivism to better understand how religious factors interact with U.S. geopolitical interests. A wide range of sources were utilized, including presidential speeches, congressional records, public opinion surveys, and academic literature from both Western and Arab perspectives. …”
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