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2501
Fabrication of biodegradable silicon nitride 3D printed nanocomposite with enhanced mechanical and antimicrobial properties for bone tissue repair
Published 2025-06-01“…Advanced materials like silicon nitride (Si3N4) exhibit enhanced osteogenic potential, toughness, and antimicrobial characteristics, providing added functionalities when fabricating 3D-printed implants for bone tissue regeneration, thus addressing the limitations of currently utilized materials. …”
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2502
Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity
Published 2025-01-01“…Person misfit did not degrade item measures or model statistics. Differential item functioning (DIF) was noted for the three easiest items on specific days. …”
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2503
Feasibility of Data Collection Via Consumer-Grade Wearable Devices in Adolescent Student Athletes: Prospective Longitudinal Cohort Study
Published 2025-06-01“…Notably, the study encountered minimal issues related to device functionality, with only 1 participant necessitating a device replacement. …”
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2504
Immunoadsorption study Mainz in adults with post-COVID syndrome (IAMPOCO)—a single-blinded sham-controlled crossover trial to evaluate the effect of immunoadsorption on post-COVID...
Published 2025-04-01“…Immunoadsorption is an extracorporeal therapy to remove circulating antibodies which is used successfully in several autoimmune diseases. We conceived the IAMPOCO trial to evaluate the therapeutic effect of immunoadsorption in patients with PCS. …”
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2505
Árbol de clasificación para la identificación de síntomas asociados a la depresión en estudiantes de una universidad pública (Classification Tree for the Identification of Symptoms...
Published 2024-03-01“…Se utilizaron los cuestionarios de Depresión de Beck-II y FANTÁSTICO para estilos de vida saludables, así como la herramienta Functional Movement Screening (FMS). La adherencia al programa se midió a través de la asistencia registrada. …”
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2506
Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review
Published 2025-01-01“…Postoperative tissue defects could be restored to their corresponding functions and aesthetic appearance through autologous tissue reconstruction, utilizing techniques such as peroneal myocutaneous flaps or iliac myocutaneous flaps, or by the implantation of artificial materials. …”
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2507
Cerium-doped Prussian blue biomimetic nanozyme as an amplified pyroptosis inhibitor mitigate Aβ oligomer-induced neurotoxicity in Alzheimer’s disease
Published 2025-03-01“…Extensive physicochemical characterization using transmission electron microscopy, X-ray photoelectron spectroscopy, and dynamic light scattering confirmed the successful synthesis of uniform nanoparticles (~ 142 nm) with preserved membrane protein functionality. …”
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2508
Intratracheal Administration of Itraconazole-Loaded Hyaluronated Glycerosomes as a Promising Nanoplatform for the Treatment of Lung Cancer: Formulation, Physiochemical, and In Vivo...
Published 2024-11-01“…The objective of this study was to utilize glycerosomes (GLY), glycerol-developed vesicles, as innovative nanovesicles for successful ITZ pulmonary drug delivery. …”
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2509
In vivo evaluation of phage therapy against Klebsiella pneumoniae using the Galleria mellonella model and molecular characterization of a novel Drulisvirus phage species
Published 2025-05-01“…Moreover, the authors developed an in vivo preclinical model of MDR infection using Galleria mellonella larvae and successfully applied it to study the bacteriophage’s therapeutic efficacy. …”
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2510
Clinical significance and prognostic value of SIRT1 genetic variants in sepsis: a multicenter hospital-based case–control study
Published 2025-07-01“…Conclusions The current research has yielded significant clinical evidence indicating that the SIRT1 rs4746720 and rs12778366 polymorphisms serve as functional variants with potential utility as prognostic markers for sepsis progression. …”
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2511
Bronchoalveolar Lavage Derived Fibroblasts From Interstitial Lung Disease Patients: A Chance to Exploit 2D/3D Model of Pulmonary Fibrosis In Vitro
Published 2025-07-01“…BAL fluids from patients with interstitial lung diseases (ILDs) can also be utilized for research purposes, offering cell populations suitable for functional and phenotypical studies. …”
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2512
Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic...
Published 2025-08-01“…HMGA1 is a crucial transcription factor in this fraction, and its knockdown impedes CRC cell proliferation, motility, and invasion. The cancer model utilizing the MKI67+ TCs subpopulation (MTRS) successfully classified patient survival and linked with immune infiltration patterns and medication responses. …”
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2513
Alternative splicing in ovarian cancer
Published 2024-10-01“…Abstract Ovarian cancer is the second leading cause of gynecologic cancer death worldwide, with only 20% of cases detected early due to its elusive nature, limiting successful treatment. Most deaths occur from the disease progressing to advanced stages. …”
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2514
Pengembangan Aplikasi Berlatih Membaca Cepat Berbahasa Inggris Berbasis Progressive Web App dengan Metode Prototyping
Published 2024-10-01“…It can be concluded that the users have successfully achieved their goals, and this application is deemed suitable. …”
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2515
Cgras2 controls growth and virulence through the regulation of intracellular cAMP level, cytoskeleton organization, and protein secretion in Colletotrichum gloeosporioides
Published 2025-08-01“…Abstract Fungal pathogens utilize intricate signaling networks to regulate growth, morphogenesis, and infection processes, enabling them to adapt to environmental cues and successfully colonize their hosts. …”
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2516
Effective Dose of Oliceridine Fumarate Co-Administered with Remimazolam in Suppressing Gastroscope Insertion Responses for Adults
Published 2025-06-01“…The time from drug administration to successful scope insertion was 2 (2, 3) minutes, and the recovery-to-discharge time was 21 (16.5, 22.5) minutes. …”
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2517
Integrating machine learning and multi-omics analysis to unveil key programmed cell death patterns and immunotherapy targets in kidney renal clear cell carcinoma
Published 2025-05-01“…Our sophisticated risk assessment model successfully identified two PCD patterns, Anoikis and lysosome-dependent cell death (LDCD), closely associated with the prognosis of KIRC patients, with the high-risk group exhibiting poor outcomes. …”
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2518
Integrating bioinformatics and machine learning to identify glomerular injury genes and predict drug targets in diabetic nephropathy
Published 2025-05-01“…Notably, as the mouse model lacks the C1orf21 gene, RT-qPCR confirmed the upregulated expression of FN1, CD36, CD48, and SRPX2. This study successfully identified five biomarkers with potential diagnostic and therapeutic value for DN. …”
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2519
LC-MS/MS based metabolomics reveals the mechanism of skeletal muscle regeneration
Published 2025-05-01“…Temporal expression analysis revealed metabolites consistent with changes in the skeletal muscle regeneration process and found that these metabolite functions were mainly enriched in inhibiting inflammatory responses, alleviating myofibrillar lysis, and promoting muscle growth. …”
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2520
Characterization of two novel chia (Salvia hispanica L.) white and black genotypes via DNA barcoding, physiological, and agronomic traits
Published 2025-09-01“…Results: DNA barcoding using five markers (trnH-psbA, matK, rpoC1, rbcL, and ITS) successfully amplified sequences of 930 bp, 1520 bp, 2295 bp, 1910 bp, and 1630 bp, respectively. …”
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