Development of a Rapid UPLC Method for Analysis of Carotenoids in Goji Berry Extract and Evaluation of Their Transformation Affected by Saponification by Bo-Yang Hsu, Chia-Hui Lin, Tsai-Hua Kao

“….), also known as wolfberry, is a traditional Chinese medicinal herb widely utilized as a functional food ingredient throughout East Asia. …”
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Preparation and Performance of Biomimetic Zebra-Striped Wood-Based Photothermal Evaporative Materials by Zebin Zhao, Wenxuan Wang, Zhichen Ba, Yuze Zhang, Hongbo Xu, Daxin Liang

“…Tannic acid-Fe ions are used as the photothermal material for functionalization. A series of stable patterned water evaporators based on delignification wood loaded with tannic acid-Fe ion complex (TA-Fe³⁺) are successfully prepared. …”
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How to Pick a Neuroprotective Drug in Stroke Without Losing Your Mind? by Joseph S. Tauskela, Nicolas Blondeau

“…Specifically, a large body of evidence shows that successive increases in OGD durations (spanning the lethal/supra-lethal continuum) require increasingly ‘strong’ drugs and combinations to adequately protect neurons (criteria not met in clinical trials). …”
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Effects of isoinertial training on muscle power, endurance, isometric strength, and balance: randomized clinical trial in patients with post-ACL reconstruction by Ramesh Chandra Patra, Som Gupta, A. Yashudas, Sanjeev Mahajan

“…Effective therapy is necessary to regain strength and functionality. While flywheel resistance training enhances strength and eccentric loading, there is limited knowledge about its effectiveness in conjunction with conventional rehabilitation methods. …”
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Rapid, high-throughput isolation of tumor specific small extracellular vesicles using radial flow microfluidic chip with IEDDA chemistry (ExoOnco ChipEpCAM−TCO) by Nnaemeka Onukwugha, Henry McEacheron, Scott Smith, Harrison Ball, Nithya Ramnath, Sunitha Nagrath

“…By implementing the rapid IEDDA chemistry and functional disulfide bridge, the improved ExoOnco Chip facilitates the isolation and release of rare TDEs, enabling further investigation of their bioactive constituents. …”
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2LE-BO-DeepTrade: an integrated deep learning framework for stock price prediction by Zinnet Duygu Akşehir, Erdal Kılıç

“…During the denoising phase, noise in the stock prices was successfully removed, and noiseless intrinsic mode functions (IMFs) were obtained. …”
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Identification and Expression Analysis of Na⁺/K⁺-ATPase and NKA-Interacting Protein in Ark Shells by Man Song, Xiao Liu, Jie Zhang, Wuping Li, Jingfen Pan, Yanglei Jia

“…This research investigated the molecular mechanisms that underpin their survival and adaptive strategies, with particular focused on sodium–potassium ATPase (NKA), a pivotal enzyme responsible for maintaining cellular ion transmembrane gradients and ensuring cellular homeostasis under stress conditions. By utilizing genome assemblies and transcriptomics datasets from multiple ark shell species, we successfully identified two distinct NKA-α subunits and two NKA-β subunits, which are essential components of the NKA complex. …”
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Laponite vs. Montmorillonite as Eugenol Nanocarriers for Low Density Polyethylene Active Packaging Films by Achilleas Kechagias, Constantinos E. Salmas, Nikolaos Chalmpes, Areti A. Leontiou, Michael A. Karakassides, Emmanuel P. Giannelis, Aris E. Giannakas

“…The target is to combine the spirit of the circular economy with the existent technology and the broadly used materials to develop a novel attractive product for active food packaging applications. Utilizing a vacuum-assisted adsorption method, eugenol was successfully intercalated into Lap and Mt nanoclays, forming EG@Lap and EG@Mt nanohybrids. …”
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Evaluating ChatGPT-4o for ophthalmic image interpretation: From in-context learning to code-free clinical tool generation by Joon Yul Choi, Tae Keun Yoo

“…Additionally, the model successfully translated schematic clinical algorithms into functional, browser-based diagnostic tools using natural language prompts alone. …”
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A Recently Patented Sleeve-Type Endotracheal Tube: Innovative Design and Clinical Prospects for Improving One-Lung Ventilation by Zhang S, Li N, Su N, Yun L, Li L, Zhi J, Lin Q, Zhu M, Li K, Zhao Z

“…After multiple rounds of structural optimization, the STET design has successfully advanced into pilot production. Preliminary validation results from small-scale manufacturing and functional testing demonstrate promising structural stability, operational flexibility, and safety performance. …”
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Angiogenesis Enhancement in a Liver Extracellular Matrix-Derived Hydrogel through Co-culture of Human Umbilical Vein Endothelial Cells and Adipose Tissue Mesenchymal Stem Cells by Masoumeh Baghalishahi, Fatemeh Pouya, Mona Saheli

“…For the successful development of this construct, the matrix must support liver cell viability, functionality, and the formation of microvasculature. …”
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Integrative analysis of seed morphology, geographic origin, and genetic structure in Medicago with implications for breeding and conservation by Seunghyun Lim, Sunchung Park, Insuck Baek, Jacob Botkin, Jae Hee Jang, Seok Min Hong, Brian M. Irish, Moon S. Kim, Lyndel W. Meinhardt, Shaun J. Curtin, Ezekiel Ahn

“…The identified candidate genes associated with geographic origin provide a foundation for future investigations into the functional mechanisms of local adaptation. Furthermore, our imputation method offers a valuable data for maximizing the utility of genomic resources in Medicago and other species.…”
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Designing a Policy Model Based on the Development of Human Capabilities of the Ministry of Education of the Kurdistan Region of Iraq by Rahman Rasul Fatah, Mojtaba Amiri, Seyed Reza Seyed Javadin, Rasool Norouzi Seyed Hosseini

“…ObjectiveThe capability approach, the result of the latest development theories, is a novel perspective that links development with the concepts of "functions" and "capabilities." This approach can be employed as a fundamental framework in the education system. …”
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Case Report: A case of occult insulinoma localized by [18F] FB (ePEG12)12-exendin-4 positron emission tomography with negative findings of selective arterial calcium stimulation te... by Kentaro Sakaki, Takaaki Murakami, Hiroyuki Fujimoto, Yoichi Shimizu, Kanae Kawai Miyake, Daisuke Otani, Shinya Otsuki, Hironori Shimizu, Kazuyuki Nagai, Takumi Nomura, Daisuke Yabe, Yuji Nakamoto, Nobuya Inagaki

“…Post-surgery, she achieved complete remission of symptoms and fully recovered.DiscussionThis case demonstrates the utility of 18F-exendin-4 PET/CT, a novel GLP-1 receptor-targeted imaging technique, in accurately localizing an occult insulinoma even with negative findings of SACST, enabling minimally invasive curative surgery.ConclusionThe 18F-exendin-4 PET/CT successfully localized an insulinoma undetectable by other methods, enabling minimally invasive curative resection. …”
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Exploring the gut microbiota associated with peripheral nerve invasion in colorectal cancer patients and constructing predictive models by Chuanbin Chen, Qingmin Chen, Shenghai Liu, Guoxi Li, Jiawei Zhao, Jingting Huang, Tianyi Ye, Xinting Yang, Zigui Huang, Zhen Wang, Fuhai He, Mingjian Qin, Chenyan Long, Binzhe Tang, Yongqi Huang, Weizhong Tang, Jungang Liu, Xiaoliang Huang

“…Abstract Objective This study aims to explore the differences in composition, abundance, and biological functions of the gut microbiota between colorectal cancer (CRC) patients with peripheral nerve invasion (PNI) and those without peripheral nerve invasion (NPNI). …”
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Rapid-Response and Highly Sensitive Boronate Derivative-Based Fluorescence Probe for Detecting H2O2 in Living Cells by Muthusamy Selvaraj, Kanagaraj Rajalakshmi, Yun-Sik Nam, Yeonhee Lee, Byoung Chan Kim, Sung Jin Pai, Sang Soo Han, Kang-Bong Lee

“…Therefore, the developed TPIOP boronate chemodosimeter was successfully utilized to visualize and quantify intracellular H2O2 from human breast cancer (MCF-7) cells, as well as gaseous and aqueous H2O2 from environmental samples using Whatman paper strips coated with TPIOP boronate.…”
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Identification of 2 novel noncoding variants in patients with Diamond-Blackfan anemia syndrome by whole genome sequencing by Ting Wen, Steven E. Boyden, Caleb M. Hocutt, Robert G. Lewis, Erin E. Baldwin, Jennie Vagher, Ashley Andrews, Thomas J. Nicholas, Alexander Chapin, Elaine M. Fan, Lorenzo D. Botto, Pinar Bayrak-Toydemir, Rong Mao, Jessica A. Meznarich

“…In case 1, hematopoietic stem cell transplant with an unaffected matched sibling donor who did not carry the variant successfully cured the congenital anemia. This study identified novel noncoding variants and underscores the clinical utility of WGS in accelerating diagnosis and improving care for rare genetic disorders, particularly when timely treatment decisions are critically important.…”
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Rapid and sensitive determination of bongkrekic acid with molecularly imprinted polymer-coated wooden-tip electrospray ionization mass spectrometry by Chunfei Zhong, Xinyan Li, Fan Zhang, Ning Liu, Jiewei Deng, Yunyun Yang, Tiangang Luan

“…A MIPWT solid phase microextraction (SPME) probe specifically tailored for BA was fabricated, by employing dummy template molecules/functional monomers in the imprinting coating modification. …”
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Coenzyme Q10 protects keratinocytes against oxidation-induced energy stress as revealed by spatiotemporal analysis of cell energetics by Roland Abi Nahed, Ali Hussein, Cécile Cottet-Rousselle, Alexandra Vogelsang, Francesco Aulicino, Imre Berger, Thomas Blatt, Julia M. Weise, Uwe Schlattner

“…Engineered from the AMP-activated protein kinase (AMPK), this sensor leverages endogenous affinities of the kinase that evolved to detect energy stress, specifically decreases in ATP/ADP and ATP/AMP ratios that pose a threat to cell survival. We successfully established HaCaT cells stably expressing AMPfret, validated their functionality by inducing energy stress with 2-deoxy-D-glucose, and demonstrated that Q10, together with high glucose conditions in culture, can enhance cellular energetics compared to low glucose controls. …”
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Whole-Genome Sequencing and Fine Map Analysis of <i>Pholiota nameko</i> by Yan He, Bo Liu, Xiaoqi Ouyang, Mianyu He, Hongyan Hui, Bimei Tang, Liaoliao Feng, Min Ren, Guoliang Chen, Guangping Liu, Xiaolong He

“…This study aimed to address that gap by employing Illumina and Nanopore sequencing technologies to perform whole-genome sequencing, de novo assembly, and annotation analysis of the <i>P. nameko</i> ZZ1 strain. Utilizing bioinformatics methods, we conducted a comprehensive analysis of the genomic characteristics of this strain and successfully identified candidate genes associated with its mating type, carbohydrate-active enzymes, virulence factors, pan-genome, and drug resistance functions. …”
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