Structure and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate by Angela Agnew, Ethan Humm, Kang Zhou, Robert P. Gunsalus, Z. Hong Zhou

“…While they are keystone organisms in the global carbon cycle and active members of the human microbiome, there is a general lack of characterization of methanogen enzyme structure and function. Through the cryoID approach, we successfully reconstructed and identified the native Methanosarcina acetivorans pyridoxal 5′-phosphate (PLP) synthase (PdxS) complex directly from cryogenic electron microscopy (cryo-EM) images of fractionated cellular lysate. …”
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A depth-wise separable VGG19-capsule network for enhanced bell pepper and grape leaf disease classification with ensemble activation by Midhun P Mathew, Sudheep Elayidom, Jagathy Raj V P, Abubeker K M

“…A noteworthy aspect of this research work is introducing an ensemble activation function, fusing Leaky Rectified Linear Unit (Leaky ReLU) and Gaussian Error Linear Unit (GELU). …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…When using software with vessel suppression function only, reading time was similar with and without software (one study). …”
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Examining the cultuling of Iranians’ concerns for others: From apathy to metapathy by Reza Pishghadam, Shima Ebrahimi

“…These utterances were collected from written texts across various sources. Subsequently, the expressions related to concern were carefully analyzed utilizing the conceptual model of cultuling analysis (CLA). …”
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A study of morpho-phonological processes in the Zanjani dialect of Azerbaijani Turkish based on optimality theory by farnaz ebadi, Mohammad Reza Oroji, Sakine Jafari, Mehri Talkhabi

“…(McCarthy, 2008: 19):     Generator  Evaluator   Input →                                → Candidates →                              →  Output Optimal Theory Model (McCarthy, 2002: 10) In order to show the function of GEN and EVAL, Optimality Theory utilizes the tables labeled as tableau. …”
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Machine learning integration of single-cell and bulk transcriptomics identifies fibroblast-driven prognostic markers in colorectal cancer by Ning Zhang, Ruiyan Liu, Siya Wu, Chenxi Feng, Boxiang Wang, Qiaoqiao Zheng, Linru Jie, Ruihua Kang, Xiaoli Guo, Xiaoyang Wang, Shaokai Zhang, Jiangong Zhang

“…Functional enrichment analyses revealed that this signature is involved in immune regulation and multiple tumor-associated cellular pathways. …”
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T-2 toxin-induced spatial learning and memory impairment in mice via the gut-brain axis and the intervening effects of resveratrol by Sheng-Quan Su, Gui-Yuan Xiong, Chun-Yan Yao, Xiao-Ling Liu, Yin-Yin Xia, Jin-Yun Long, Xiu-Kuan Li, Liang-Mei Wang, Long Yi, Wu-Wei Xu, Wu-Qiang Lu, Qian-Qian Li, Ting Hu, Hao Liu, Ke-Xue Wang, Peng Luo, Tong-Jian Cai

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Identification of mesoscale eddies based on improved YOLOv8 model: a case study in the South China Sea by Jianhao Gao, Jianhao Gao, Jianhao Gao, Feng Zhou, Feng Zhou, Feng Zhou, Di Tian, Di Tian, Muping Zhou, Muping Zhou, Hailong Guo

“…Due to its feature analysis and generalization capability, the YOLOv8 can successfully captures some mesoscale eddies undetected by the PET, thus track more mesoscale eddy trajectories. …”
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Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease by Linh T. Ngo, Michaella J. Rekowski, Devin C. Koestler, Takafumi Yorozuya, Atsushi Saito, Imaan Azeem, Alexis Harrison, M. Kristen Demoruelle, Jonathan Boomer, Bryant R. England, Paul Wolters, Philip L. Molyneaux, Mario Castro, Joyce S. Lee, Joshua J. Solomon, Koji Koronuma, Michael P. Washburn, Scott M. Matson

“…Results Proteomic profiling successfully differentiated IIP from controls. k-means clustering based on protein expression revealed three distinct IIP clusters, which were not associated with age, smoking history, or baseline pulmonary function. …”
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Multi-omics data reveal that SAA1 + fibroblasts exacerbate periodontitis by regulating macrophage inflammation and chemotaxis by Li Li, Yuting Yang, Fang Dai, Libin Deng, Meixiu Jiang, Chenjiang He, Ting Long, Kaiqiang Yang, Xinbo Yang, Li Song

“…Results This study successfully constructed a single-cell transcriptome atlas comprising 65,979 periodontal tissue cells and identified an SAA1 + fibroblast subpopulation with key functions. …”
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Changes in heart rate variability induced by E-sports activities by Ti Wu, Po-Yao Lee, Jie-An Tu, Hsin-Huan Wang, Hsin-Huan Wang, Hsueh-Chin Chao, Chia-Hsiang Chen, Jui-Hung Tu

“…., Standard Deviation of NN intervals (SDNN), Root Mean Square of Successive Differences (RMSSD), Number of NN intervals differing by more than 50 ms (NN50), Percentage of NN50 (pNN50)] and high-frequency (HF) power and LF/HF Ratio were significantly higher than those recorded during and after gaming (p < 0.05).ConclusionE-sports gaming imposes stress and fatigue on HRV-related parameters, heightening sympathetic activity and suppressing parasympathetic function. …”
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Identification of Factors Affecting Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…Risk management is now an important part of project management and has a specific function for improving the efficiency of implementing the project, saving prices, and improving the profitability of projects. …”
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Liposomal ellagic acid enhances the regenerative potential of ADMSC-laden nanofibrous PCL scaffolds in a rat model of spinal cord injury by Arman Abroumand Gholami, Shokoufeh Rahmani, Payam Moharreri, Esmael Amirazodi, Amir Mahdi Molavi, Tahere Mokhtari, Fatemeh Tahmasebi, Amirhossein Rabiei Rad, Hamideh Babaloo

“…Throughout the study, the motor function of the animals was monitored. After six weeks, the rats were subjected to real-time PCR and histological analysis, utilizing Cresyl Violet/Luxol Fast Blue staining and evaluating the expression of the genes COX2, GPX1, MBP, and Slc17a6/7. …”
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Rough-and-Refine Model for Scene Graph Generation by Li Junliang, Lv Shirong, Li Wei

“…Existing scene graph generation methods have achieved significant success. However, most models suffer from either having too many parameters or making inaccurate judgments regarding predicates. …”
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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…Transition probabilities pertaining to low-dose ICS were adjusted by relative risks for asthma control and exacerbations for alternative treatments, derived from a NMA. Health state utilities were identified from literature sources. …”
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Architecture and the Time of Space by Deborah Hauptman

“…As Foucault suggested, one of the great problems that arose in the 1950s was that of the political status of science and the ideological functions that it could serve. Another rebuke can be seen as the challenge to the primacy of truth as an adequation of subject to thing. …”
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Comparative analysis of microwave indices for freeze/thaw state monitoring and adaptive thresholding implications by Zhicheng Yang, Tianjie Zhao, Qingfeng Wang, Lihua Peng, Youhua Ran, Yu Bai, Jingyao Zheng, Panpan Yao, Zhiqing Peng, Jinbiao Zhu, Xiaokang Kou, Yuei-An Liou, Jiancheng Shi

“…The evaluation was conducted across six soil moisture and temperature networks spanning the Tibetan Plateau (Maqu, Naqu, Pali, Shiquan River, SMN-WDL) and Inner Mongolian Plateau (SMN-SDR), utilizing both the Threshold - based Algorithm (TA) and Discriminant Function Algorithm (DFA). …”
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Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization by Shundong Cai, Mengdie Li, Jinfa Ye, Mingyou Zhang, Jingbin Zhuang, Yuhang Cheng, Hongjin Li, Lang Ke, Xingyuan Wei, Yun Han, Huanhuan Liu, Gang Liu, Chengchao Chu

“…ABSTRACT Corneal neovascularization (CNV) is a debilitating ocular surface disease that severely compromises visual function and carries a significant risk of vision loss. …”
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Sialyltransferase gene signature as a predictor of prognosis and therapeutic response in kidney renal clear cell carcinoma by Huiyu Liu, Changwei Zhou, Zaichun Yan, Hairong Yang, Yun Zhao, Rui Tian, Xuejun Bo, Leizuo Zhao, Wei Ren

“…Differentially expressed sialylation genes were identified using the "limma" package, and their functional enrichment was assessed via Gene Ontology GO and KEGG analyses. …”
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Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis by Zhao D, Zhuang J, Wang L, Wu L, Xu W, Zhao L, Hong J, Jin W, Miao C

“…Deterioration of cardiac function, elevated inflammatory markers such as IL-1β, IL-6, and increased cardiac injury biomarkers such as cTnI indicated the successful establishment of our SCM model. …”
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