Integrated multi-omics identify key signalling pathways for notochord lumenogenesis in ascidian Ciona savignyi by Jin Zhang, Zicheng Tan, Qishu Qin, Hongzhe Peng, Wenjie Shi, Haiyan Yu, Bo Dong

“…Meanwhile, we identified that CDC42 was a potential downstream target factor of the Ras-Rap1-MAPK signalling axis, playing crucial functions in notochord lumenogenesis. Overall, we systematically revealed the key regulatory signalling pathways for notochord lumen formation and verified a lumenogenesis-related signalling axis, providing a foundational data resource for exploring the mechanisms of lumenogenesis.…”
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Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry by Safaa Salah El-Din Taha, Osama Abd El-Hamid Ibrahim, Einas Hamed El-Shatoury, Amany Mohamed El-Deeb, Hayam Abd El-Naby Sayed

“…A peak β-galactosidase activity of 5.523 U/ ml was recorded at a pH 7, a lactose concentration of 4.6 %, UF-cheese permeate serving as a carbon source, 2 % potassium nitrate (KNO₃) as a nitrogen source, an inoculum size of 5%, and incubated at 37 ºC for 24 h. …”
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Mediator MED23 controls oligodendrogenesis and myelination by modulating Sp1/P300-directed gene programs by Shuai Zhang, Xue Feng, Chong-Hui Li, Yuan-Ming Zheng, Meng-Ya Wang, Jun-Jie Li, Yun-Peng Dai, Naihe Jing, Jia-Wei Zhou, Gang Wang

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Glucose Sensing in Saliva by Jacopo Giaretta, Riccardo Zulli, Theja Prabhakar, Ronil J. Rath, Sina Naficy, Sara Spilimbergo, Paul S. Weiss, Syamak Farajikhah, Fariba Dehghani

“…Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. …”
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GINS1 is a prognostic biomarker and correlated with methylation and immune escape in liver hepatocellular carcinoma by Mingchao Liang, Tianqi Lai, Tianqi Lai, Zhen Li, Wei Yu, Mingrong Cao, Nan Yao, Youzhu Hu, Youzhu Hu, Tongzheng Liu, Junjie Liang

“…Enrichment analyses were conducted to investigate the functions of GINS1. To assess the genetic alterations, methylation, and prognostic value, cBioPortal, and MethSurv databases were utilized. …”
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Integrated analysis of single-cell and bulk transcriptomics reveals cellular subtypes and molecular features associated with osteosarcoma prognosis by Feng Liu, Tingting Zhang, Yongqiang Yang, Kailun Wang, Jinlan Wei, Ji-Hua Shi, Dong Zhang, Xia Sheng, Yi Zhang, Jing Zhou, Faming Zhao

“…Moreover, the study investigated the impact of ATF6α in OS aggressiveness through genetic and pharmacological loss of function analyses. Lastly, the CellChat algorithm was employed to investigate cell-cell communications. …”
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Characterization of a GH43 Bifunctional Glycosidase from Endophytic <i>Chaetomium globosum</i> and Its Potential Application in the Biotransformation of Ginsenosides by Yao Lu, Qiang Jiang, Yamin Dong, Runzhen Ji, Yiwen Xiao, Du Zhu, Boliang Gao

“…The GH43 family of glycosidases represents an important class of industrial enzymes that are widely utilized across the food, pharmaceutical, and various other sectors. …”
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Fine Tuning of Hepatocyte Differentiation from Human Embryonic Stem Cells: Growth Factor vs. Small Molecule-Based Approaches by Divya S. Varghese, Thilina Thejinda Alawathugoda, Suraiya A. Ansari

“…The directed differentiation of hESCs into hepatocytes could provide an invaluable source of liver cells for various liver-based applications. …”
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Mitochondrial genome assembly and comparative analysis of decaploid Camellia hainanica by Shihui Zhang, Yuyan Zhang, Sheng Luo, Jie Gao, Haiyan Hu, Jinping Liu, Wenqiang Wu, Jian Wang, Xiaolong Huang, Hanggui Lai, Hanggui Lai, Dongyi Huang

“…Results also provided key data support for the utilization and conservation of tea oil germplasm resources and the breeding of varieties and are of great significance for promoting genetic evolution research, genetic breeding, and identification of tea oil Camellia.…”
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Intestinal Effects of Brewers’ Spent Grain Extract In Ovo (<i>Gallus gallus</i>)—A Pilot Study by Melissa Y. Huang, Louisa M. Smieska, Elad Tako

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The responses of vegetation water use efficiency to biomass density and CO2 balance in dryland of Central Asia during 21st century by Alphonse Kayiranga, Xi Chen, Xuexi Ma, Dative Ingabire, Tie Liu, Yaoming Li, Emeka Edwin Igboeli, Eldiiar Duulatov, Hubert Hirwa, Clement Nzabanita, Ping Hu

“…Water-use efficiency (WUE) is a critical component that links plant carbon (CO2) and water cycles through various aspects of plant ecosystem functioning. However, the variations of plant CO2 in response to water use efficiency (WUE) across temperate dryland ecosystems remains inadequately understood. …”
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A Novel Signature Composed of Hypoxia, Glycolysis, Lactylation Related Genes to Predict Prognosis and Immunotherapy in Hepatocellular Carcinoma by Feng Yi, Shichao Long, Yuanbing Yao, Kai Fu

“…Subsequently, the single sample Gene Set Enrichment Analysis (ssGSEA), Tumor Immune Estimation Resource (TIMER) and Tumor Immune Dysfunction and Exclusion (TIDE) algorithms were utilized to assess immune infiltration and immune evasion. …”
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ESSegNeXt: A Novel Building Extraction Framework Based on Generalized SamGeo and SegNeXt Models Using High-Resolution Remote Sensing Images by Qi Lu, Wensong Liu, Lianpeng Zhang, Erzhu Li, Junlong Qiu, Lei Wang

“…Additionally, an edge-preserving loss function was introduced to enhance the boundary detection capability of the SegNeXt model using edge features extracted by SamGeo during cyclic validation. …”
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Exploring the Causes of Severe Fluctuations in Water Surface Area Using Water Index and Structural Equation Modeling: Evidence from Ebinur Lake, China by Mengfan Li, Changjiang Liu, Fei Zhang, Ngai Weng Chan, Elhadi Adam, Weiwei Wang, Yingxiu Wu

“…Arid zone lakes function as indicators of watershed ecology and environment, significantly influencing regional social development. …”
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Unfavourable results in thumb reconstruction by Samir M Kumta

“…With refinements in microsurgery, the foot has become a major source of tissue for component replacement in the thumb. …”
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Recapitulating the bone extracellular matrix through 3D bioprinting using various crosslinking chemistries by Laurens Parmentier, Edward Vermeersch, Sandra Van Vlierberghe

“…Bioprinting allows to spatially organize cellular niches influencing mechanobiology into tissue engineered constructs thereby aiming to achieve a similar functional complexity as the various tissues present within bone. …”
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Genome-Wide Identification and Expression Analysis of Hexokinase Gene Family Under Abiotic Stress in Tomato by Jing Li, Xiong Yao, Jianling Zhang, Maoyu Li, Qiaoli Xie, Yingwu Yang, Guoping Chen, Xianwei Zhang, Zongli Hu

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Growth patterns and heat tolerance analysis of dwarf chicken with frizzled feather by Guo Li, Tingting Xie, Zijing Zhu, Chengfeng Bin, Sadaqat Ali, Dongxue Guo, Xiaotong Wang, Lei Li, Xunhe Huang, Bing Zhang, Li Zhang

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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

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Impact of continuous cropping on microbial biomass and enzyme activities in the surface layer of gravel-sand mulched soils in arid Northwest China: A Meta-analysis by XUE Yinmin, JIA Zhenjiang, MA Dongxiang, WU Yangyang, HUANG Yahao, HE Xuezhong, WU Xiu, LI Wangcheng

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