Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…In vitro experiments were conducted with the primary objective of appraising both the expression profile and the precise functional attributes of SMAD3 within the milieu of Liver Hepatocellular Carcinoma (LIHC). …”
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Designing accessible and independent living spaces for visually impaired individuals: a barrier-free approach to interior design by Anushka Patil, Smruti Raghani

“…Adaptive design offers solutions that utilize sensory input, spatial predictability, and barrier-free layouts to address these challenges. …”
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أثر الدين في التوجهات الجيوبوليتيكية للولايات المتحدة الأمريكية تجاه إسرائيل by عيسى السيد عيسى دسوقي, حسن قطب حسن قطب

“…It is grounded in a theoretical framework that integrates political realism and constructivism to better understand how religious factors interact with U.S. geopolitical interests. A wide range of sources were utilized, including presidential speeches, congressional records, public opinion surveys, and academic literature from both Western and Arab perspectives. …”
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Inducible engineering precursor metabolic flux for synthesizing hyaluronic acid of customized molecular weight in Streptococcus zooepidemicus by Rui Zhao, Jun Li, Yingtian Li, Xujuan Pei, Jingyi Di, Zhoujie Xie, Hao Liu, Weixia Gao

“…The molecular weight (MW) of HA is crucial for its biological functions. Streptococcus zooepidemicus, a prominent HA industrial producer, naturally synthetizes HA with high MW. …”
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Uncertainty-Aware Active Meta-Learning for Few-Shot Text Classification by Sanghyun Seo, Hiskias Dingeto, Juntae Kim

“…Our findings suggest that this methodology can be effectively utilized in a wider range of application areas, opening new avenues for future research in low-resource natural language understanding.…”
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Systematic analyses of the MIR172 family members of Arabidopsis define their distinct roles in regulation of APETALA2 during floral transition. by Diarmuid S Ó'Maoiléidigh, Annabel D van Driel, Anamika Singh, Qing Sang, Nolwenn Le Bec, Coral Vincent, Enric Bertran Garcia de Olalla, Alice Vayssières, Maida Romera Branchat, Edouard Severing, Rafael Martinez Gallegos, George Coupland

“…Through genome editing and detailed confocal microscopy, we show that the activity of miR172 at the shoot apex is encoded by 3 MIR172 genes, is critical for floral transition of the shoot meristem under noninductive photoperiods, and reduces accumulation of AP2 and TARGET OF EAT2 (TOE2), an AP2-LIKE TF, at the shoot meristem. Utilizing the genetic resources generated here, we show that the promotion of flowering by miR172 is enhanced by the MADS-domain TF FRUITFULL, which may facilitate long-term silencing of AP2-LIKE transcription, and that their activities are partially coordinated by the TF SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 15. …”
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Trait-mediated responses and co-occurrence patterns of breeding steppe birds under human footprint in Inner Mongolia by Wenyu Xu, Chunlu Wang, Yanqi Wang, Xi Yang, Lishi Zhang, Piotr Tryjanowski, Frédéric Jiguet, Zheng Han, Haitao Wang

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Identification of intratumoral bacteria that enhance breast tumor metastasis by Zachary J. Gerbec, Antonio Serapio-Palacios, Avril Metcalfe-Roach, Zakhar Krekhno, Haggai Bar-Yoseph, Sarah E. Woodward, Jorge Pena-Díaz, Oksana Nemirovsky, Shannon Awrey, Sebastian H. Moreno, Sean Beatty, Esther Kong, Nina Radisavljevic, Mihai Cirstea, Shawn Chafe, Paul C. McDonald, Sam Aparicio, B. Brett Finlay, Shoukat Dedhar

“…We also identified enrichment of specific bacterial functions, providing insight into possible sources of bacteria-driven increases in the metastatic potential of multiple cancer types.…”
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Integrating voltammetry and substrate-enhanced luminescence for noninvasive glucose sensing by Gabriel López-Peña, Ana Pallarés Vilar, Aida Jaafar, Silvia Simón-Fuente, Antonio Arranz, Maria Ribagorda, Miguel Manso-Silván, Emma Martín Rodríguez

“…The sensor incorporates NaGdF4:20% Yb3+, 2% Er3+ nanoparticles (YbEr-NPs) immobilized on a PSi substrate functionalized with a phenylboronic ester molecule. The YbEr-NPs enable luminescence-based sensing, exploiting the sensitivity of Er3+ ions to the OH vibrational groups present in D-glucose. …”
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Efficient exploration of electronic and dielectric properties using advanced first-principles analysis grounded in modern theory of polarization: Application to PbTiO3 by Aimad Belboukhari, Souad Ait Saghir, Abderrahim Bakak, Said El-Jallal, Khaled Ait Bentaleb, My Abdelaziz Koumina, Daoud Mezzane, Yaovi Gagou

“…Especially with the increased availability of powerful computational resources and techniques. Building upon these advancements, our contribution aims to elucidate an efficient methodology for studying electronic and dielectric properties by applying the Berry phase and Maximally Localized Wannier functions methods. …”
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Fruit quality evaluation of different mulberry varieties by Jie Tian, Haichao Wen, Bingxiang Liu, Xinyuan Tian, Yibo Wu, Jingyan Yang, Bingying Zhang, Hongjiao Li

“…The mulberry tree, as a plant resource that serves both medicinal and dietary purposes, contains rich nutritional components and various bioactive compounds. …”
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Research on Stacking Distribution of Steel Plates Input Based on Improved Multi-objective Particle Swarm Optimization by ZHONG Chuanjie, CHENG Wenming, DU Run, GAO Xuchao, ZHANG Lin

“…The inventory balance index was established based on the standard deviation of the number of steel plates allocated to each reservoir to fully mobilize and balance material storage resources during operation. These three indices were utilized to evaluate the degree of stack allocation and served as the objective function to establish a multi-objective decision optimization model for the stack allocation problem of steel plates. …”
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A lightweight algorithm for steel surface defect detection using improved YOLOv8 by Shuangbao Ma, Xin Zhao, Li Wan, Yapeng Zhang, Hongliang Gao

“…Firstly, GhostNet is utilized as the backbone network in order to reduce the number of model parameters and computational complexity. …”
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Characteristic Fingerprint Based on Low Polar Constituents for Discrimination of Wolfiporia extensa according to Geographical Origin Using UV Spectroscopy and Chemometrics Methods by Yan Li, Ji Zhang, Yanli Zhao, Zhimin Li, Tao Li, Yuanzhong Wang

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Positioning, navigation, and timing on the Moon and Mars with galactic cosmic rays by G. Leone, H.K.M. Tanaka, M. Holma, S. Krishnan, A.R. Duffy, T. Enqvist, P. Kuusiniemi, J. Joutsenvaara, G. Cerretto, E. Cantoni, M. Sellone, J. Marteau, D. Lo Presti, J.G. Szűcs, D. Varga

“…The density maps obtained by muography can also show the eventual presence of valuable metals, minerals, or water ice for in-situ resource utilization (ISRU). MuWNS’ broad spectrum of applications is crucial for the first deployment and then the correct functioning of an underground base on the Moon or Mars.…”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…Fatty acids, among other substrates, are utilized by immune cells as an energy source. Therefore, L-carnitine, which is authorized as a feed additive in cattle, may influence the metabolism of peripheral blood mononuclear cells (PBMC) during an immune challenge. …”
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Developing and evaluating an intelligent integration system for older adult care and health based on the sport-medicine-tourism model by Xiaoxue Ma, Xiaofei Fang, Shuqian Liu, Xueqing Wang, Ping Wang, Fugao Jiang

“…The findings demonstrate significant improvements in the experimental group across all health dimensions (p < 0.05), and the system was rated as “Good” in functional utility, service quality, and user satisfaction. …”
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SurfaceVision: An Automated Module for Surface Fault Detection in 3D Printed Products by Laukesh Kumar, Manoj Kumar Satyarthi

“…This paper introduces SurfaceVision, an automated system for surface fault detection in 3D printed products, leveraging the ResNet-18 architecture as the backbone. Our framework utilizes a combination of contrastive learning and multi domain loss function to identify and classify defects with high accuracy. …”
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Digital Governance Policy Implementation Model Through Electronification of Land and Building Acquisition Fees (E-BPHTB) at the Baubau City Regional Revenue Agency by Rahmawati Rahmawati

“…The results of the study indicate that the implementation of the Electronic policy (Land and Building Acquisition Fee) at Bapenda Baubau City is quite good, but not as expected: Organization in terms of budgeting, and methods are good but the human resources owned are still lacking, not adequate especially in the field of determination in the process of completing duties and functions. …”
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Extreme Warming Coordinately Shifts Root and Leaf Traits of Alpine Plants toward Conservatism by Jingya Zhang, Jianghui Chen, Yixuan Huang, Luhang Jiang, Ziyi Zheng, Huimin Zhou, Hao Wang, Huiying Liu

“…Trait network analysis further supported this view, showing that extreme warming increased root edge density and decreased leaf modularity, indicating a more integrated network of leaf and root traits to enhance resource utilization efficiency. Our findings suggest that extreme warming may drive a coupled shift toward more conservative traits in both leaves and roots within alpine grasslands, with significant implications for predicting future ecosystem dynamics under escalating climate extremes.…”
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