Analysis of Human Gut Microbiota Enzymes for Biotechnological and Food Industrial Applications by Alfonso Torres-Sánchez, Gracia Luque, Pilar Ortiz, Alicia Ruiz-Rodríguez, Ana López-Moreno, Margarita Aguilera

“…The human gut microbiota is a complex and dynamic ecosystem, recognized for its valuable and wide array of physiological functions. This study investigated the human gut microbiota as a source of enzymes for innovative applications in the biomedicine, bioremediation, and food and feed biotechnological industries by integrating data from combined in silico and in vitro approaches. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Data sources Questionnaires to participants for patient-reported outcome measures, and National Health Service England Hospital Episode Statistics and mortality data. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Data sources Questionnaires to participants for patient-reported outcome measures, and National Health Service England Hospital Episode Statistics and mortality data. …”
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Activity tracking devices in pregnancy: Understanding the participant experience in a longitudinal birth cohort by Ashley Redding, Dionne Coates, Andrea E. Cassidy-Bushrow, Jennifer K. Straughen, Sara Santarossa

“…Participants preferred to receive PA information from a trusted healthcare source (e.g., doctor, nurse, or other healthcare provider), though most participants (57%) did not receive PA information during prenatal care. …”
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Discrimination of Farming Practices Through Olive Leaf Phenolic and Mineral Analysis by Mario Franić, Igor Pasković, Šime Marcelić, Igor Lukić, Nikola Major, Igor Palčić, Smiljana Goreta Ban, Marija Polić Pasković

“…The results of this study have the potential to be utilized for the enhanced production of organic olive leaves as a reliable source of valuable phytochemicals for nutraceuticals, functional foods, and dietary supplements.…”
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Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05 by Randa Harrat, Ghania Bourzama, Gaëtan Burgaud, Emmanuel Coton, Aymen Bourezgui, Boudjema Soumati

“…These isolates were then tested for their ability to biodegrade LDPE films and utilized as the sole carbon source <i>in vitro</i> in a mineral salt medium (MSM). …”
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Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria by Candice L. Wilshire, Carson C. Fuller, Christopher R. Gilbert, John R. Handy, Kimberly E. Costas, Brian E. Louie, Ralph W. Aye, Alexander S. Farivar, Eric Vallières, Jed A. Gorden

“…The electronic medical record (EMR) is a source of clinical information that could identify high-risk populations for LCS, including a diagnosis of COPD; however, an unsubstantiated COPD diagnosis in the EMR may lead to inappropriate LCS referrals. …”
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AnVILWorkflow: A runnable workflow package for Cloud-implemented bioinformatics analysis pipelines [version 1; peer review: 2 approved] by Sean Davis, Marcel Ramos, Michael C. Schatz, Kai Gravel-Pucillo, Levi Waldron, Sehyun Oh, Martin Morgan, Vincent Carey

“…AnVILWorkflow simplifies the setup of the cloud computing environment, input data formatting, workflow submission, and retrieval of results through intuitive functions. We demonstrate the utility of AnVILWorkflow for three use cases: bulk RNA-seq analysis with Salmon, metagenomics analysis with bioBakery, and digital pathology image processing with PathML. …”
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Integrated single-cell analysis reveals the regulatory network of disulfidptosis-related lncRNAs in bladder cancer: constructing a prognostic model and predicting treatment respons... by Jiafu Xiao, Jiafu Xiao, Jiafu Xiao, Wuhao Liu, Wuhao Liu, Wuhao Liu, Jianxin Gong, Jianxin Gong, Jianxin Gong, Weifeng Lai, Weifeng Lai, Weifeng Lai, Neng Luo, Neng Luo, Neng Luo, Yingfan He, Junrong Zou, Junrong Zou, Zhihua He, Zhihua He, Zhihua He

“…This study aims to investigate disulfidptosis-related lncRNAs (DRLs) as potential prognostic markers for BLCA patients.MethodsUtilizing single-cell sequencing data, RNA sequencing data, and corresponding clinical information sourced from the GEO and TCGA databases, this study conducted cell annotation and intercellular communication analyses to identify differentially expressed disulfide death-related genes (DRGs). …”
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Context-Aware Gene Embedding Pipeline (CGEP): An Accessible, Regulatory-Region-Inclusive Embedding Framework for Interpretable Disease-Agnostic Prediction by Twaha Ahmed Minai, Zubair Ahmed Shaikh, Asim Imdad Wagan, M. Kamran Azim, Syed Muhammad Muaz, Muhammad Shoaib Siddiqui

“…In this study, we propose a novel Gene Embedding Pipeline (CGEP) designed to address critical limitations in genomic deep learning by integrating both functional and regulatory genomic contexts. Unlike conventional approaches, our framework prioritizes disease-associated genes identified through contribution analysis (validated via a breast cancer case study) while remaining extensible to all pathologies with patient-derived FASTA sequences. …”
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CD105+ fibroblasts support an immunosuppressive niche in women at high risk of breast cancer initiation by Eric G. Carlson, Jennifer C. Lopez, Yukiko Yamaguchi, Jackson Gibson, Saul J. Priceman, Mark A. LaBarge

“…Abstract Background Aging is the greatest risk factor for breast cancer, and although epithelial cells are the source of carcinomas, epithelial changes alone do not fully explain cancer susceptibility. …”
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Creating custom 3D printing material colors using optical modeling of waste plastic by Kimia Aghamohammadesmaeilketabforoosh, Joshua Givans, Morgan Woods, Joshua Pearce

“…To enable prosumers to create custom colors from their own recycled 3D printing waste this article presents a new open-source software named SpecOptiBlend. Specifically, this study introduces a novel method for customizing color filaments by recycling waste 3D printing samples, thereby enhancing the capabilities of color 3D printing. …”
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FPGA-accelerated SpeckleNN with SNL for real-time X-ray single-particle imaging by Abhilasha Dave, Cong Wang, James Russell, Ryan Herbst, Jana Thayer

“…The new implementation, while reducing the parameter count to 64.6K (a 98.8% reduction), focuses on maintaining the model's essential functionality for real-time operation, achieving an accuracy of 90%. …”
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Lack of Amino Acid Alterations Within the Cochlear Nucleus and the Auditory Cortex in Acoustic Trauma-Induced Tinnitus Rats Using In Vivo Microdialysis by Shanshan Yuan, Huey Tieng Tan, Paul F. Smith, Yiwen Zheng

“…<b>Background/Objectives:</b> Tinnitus is a debilitating auditory disorder commonly described as a ringing in the ears in the absence of an external sound source. Sound trauma is considered a primary cause. …”
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Adaptation mechanisms of Alcanivorax facilitating its predominance in marine environments by Zhen Chen, Zhen Chen, Zhen Chen, Shizheng Xiang, Shizheng Xiang, Shizheng Xiang, Yao Lu, Yao Lu, Yao Lu, Qiliang Lai, Qiliang Lai, Qiliang Lai, Chunming Dong, Chunming Dong, Chunming Dong, Jianyang Li, Jianyang Li, Jianyang Li, Guizhen Li, Guizhen Li, Guizhen Li, Zongze Shao, Zongze Shao, Zongze Shao

“…However, Alcanivorax bacteria perform sulfide detoxification through Sqr rather than by gaining energy via sulfide oxidation Although no strain was confirmed to be chemoautotrophs, we discovered that the two clades, A. xenomutans and A. profundimaris, can grow under conditions with very low organic matter.DiscussionThe ability to utilize inorganic compounds as a supplementary energy source and adapt to carbon oligotrophic growth may contribute to the prevalence of Alcanivorax in marine ecosystems.…”
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A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions by Wataru Kitagawa, Wataru Kitagawa, Kensuke Igarashi, Ryo Nagasawa, Shigeyuki Kakizawa, Mizuki Horino, Kosuke Fujishima, Kosuke Fujishima, Toshiaki Fukui, Souichiro Kato, Souichiro Kato, Souichiro Kato

“…This study aimed to establish a promoter library that functions in C. necator grown under autotrophic conditions. …”
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Lactic Acid Bacteria and Yeast Fermentation to Improve the Nutritional Value of <i>Ulva rigida</i> by Marta Brandão, Diogo J. Marques, Sofia Sousa, Marília Mateus, Helena M. Pinheiro, M. Manuela R. da Fonseca, Carla Pires, Maria Leonor Nunes, António Marques, M. Teresa Cesário

“…Given its abundance and nutrient-rich profile, the green macroalga <i>Ulva rigida</i> is a promising alternative protein source. However, the bioaccessibility of its proteins is hindered by an embedding matrix of ulvan, a gel-forming polysaccharide. …”
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A Model-Driven Approach Employing DSL and Generation Templates to Accelerate the Development of Conversational Agents for Smart Tourism by Charaf Ouaddi, Lamya Benaddi, Adnane Souha, Hamza Abdelmalek, Abdeslam Jakimi, Rachid Saadane

“…Additionally, developers and companies often utilize APIs provided by intent recognition services like Dialogflow and Amazon Lex to easily create conversational agents using graphical forms, which enhance conversational agent functionality. …”
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NORDIC denoising on VASO data by Lasse Knudsen, Lasse Knudsen, Luca Vizioli, Federico De Martino, Lonike K. Faes, Daniel A. Handwerker, Steen Moeller, Peter A. Bandettini, Peter A. Bandettini, Laurentius Huber

“…The use of submillimeter resolution functional magnetic resonance imaging (fMRI) is increasing in popularity due to the prospect of studying human brain activation non-invasively at the scale of cortical layers and columns. …”
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Pancreatic β-cells package double C2-like domain beta protein into extracellular vesicles via tandem C2 domains by Diana Esparza, Carinna Lima, Sarah Abuelreich, Ima Ghaeli, Jinhee Hwang, Eunjin Oh, Ayelet Lenz, Angel Gu, Nan Jiang, Fouad Kandeel, Debbie C. Thurmond, Tijana Jovanovic-Talisman

“…Moreover, in rat clonal β-cells, we probed domains required for DOC2B sorting into EVs.MethodUsing Single Extracellular VEsicle Nanoscopy, we quantified EVs derived from clonal β-cells (human EndoC-βH1, rat INS-1 832/13, and mouse MIN6); two other cell types known to regulate glucose homeostasis and functionally utilize DOC2B (skeletal muscle rat myotube L6-GLUT4myc and human neuronal-like SH-SY5Y cells); and human islets sourced from individuals with no diabetes (ND). …”
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