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361
RTP4, a Biomarker Associated with Diagnosing Pulmonary Tuberculosis and Pan-Cancer Analysis
Published 2023-01-01“…Pulmonary tuberculosis (PTB) is a global epidemic of infectious disease; the purpose of our study was to explore new potential biomarkers for the diagnosis of pulmonary tuberculosis and to use the biomarkers for further pan-cancer analysis. Methods. Four microarray gene expression sets were downloaded from the GEO public databases and conducted for further analysis. …”
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362
Citrus flavonoids for overcoming breast cancer resistance to methotrexate: identification of potential targets of nobiletin and sinensetin
Published 2025-03-01“…Protein targets of citrus flavonoids were identified from multiple databases and were collected using Venny 2.1. Microarray data of MCF-7 and MCF-7/MTX cells were acquired from the Gene Expression Omnibus. …”
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363
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Published 2018-01-01“…Methods. lncRNA and mRNA profiling of PBMCs from 17 smokers and 14 COPD subjects was detected by high-throughput microarray. The expression of dysregulated lncRNAs was validated by qPCR. …”
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364
NF1 expression profiling in IDH-wildtype glioblastoma: genomic associations and survival outcomes
Published 2024-10-01“…Methods We assembled a single-institution, retrospective cohort of 542 IDH-wildtype GBM with somatic next generation sequencing to investigate the frequency and nature of detected NF1 alterations. We selected 69 GBMs from which to build a tissue microarray (TMA) of 44 NF1-wildtype and 25 NF1-mutant cases. …”
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365
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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366
A retrospective analysis of prenatal genetic results in fetal hydronephrosis.
Published 2025-01-01“…<h4>Objective</h4>To discuss the application value of technologies such as chromosome microarray analysis (CMA) in fetuses with hydronephrosis and pyelectasis.…”
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367
Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease
Published 2024-12-01“…Here, we analyzed the GSE 30529 microarray datasets of human tubulointerstitial tissue samples from the Gene Expression Omnibus database (GEO). …”
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368
Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma
Published 2025-04-01“…Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers. …”
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369
Screening and identification of potential target of 1′-acetoxychavicol acetate (ACA) in acquired lapatinib-resistant breast cancer
Published 2024-12-01“…We identified differentially expressed genes (DEGs) using GSE16179 microarray data. DEGs from ACA-treated and lapatinib-resistant cells were analyses using Panther DB, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and protein-protein interaction (PPI) network analysis. …”
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370
HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer
Published 2025-03-01“…However, there are no studies on the immunological aspects of HDAC1 in non-small cell lung cancer (NSCLC).Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate HDAC1 expression and prognosis in NSCLC. …”
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371
Bayesian inference towards the resolution of molecular evolution: application to the “Trichoderma harzianum sensu lato” clade
Published 2004-07-01“…The clade containing the ex-neotype strain of T. harzianum included exclusively clonally propagating isolates from temperate climates, and was clearly distinguished from all other “H. lixii/T. harzianum” lineages by multivariate analysis of phenotype microarray data. We propose that only this lineage should be regarded as T. harzianum sensu stricto, and that the other lineages be regarded as T. harzianum sensu lato until phenetic characters have been defined which allow their description as separate taxa.…”
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372
A retrospective analysis of 6942 amniocentesis cases
Published 2025-08-01“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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373
Prevalence and Diversity of <i>Staphylococcus aureus</i> in Bulk Tank Milk from Community-Based Alpine Dairy Pastures in Tyrol, Austria
Published 2025-07-01“…A total of 140 isolates collected from the 94 <i>S. aureus</i>-positive community-based Alpine dairy pastures revealed 33 distinct <i>spa</i> types, with t2953 (<i>n</i> = 33), t529 (<i>n</i> = 12), t267 (<i>n</i> = 11), and t024 (<i>n</i> = 10) being the most common. Selected isolates representing the different <i>spa</i> types were characterised by DNA microarray-based genotyping, multi-locus sequence typing (MLST), and antimicrobial susceptibility testing. …”
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374
Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms
Published 2025-06-01“…Additionally, we processed the GSE53873 microarray dataset, which includes 19 pemphigus samples and 5 controls. …”
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375
Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects
Published 2025-01-01“…However, further data are required to clarify ADORA3 expression patterns in liver cancer, mechanisms of action, and the potential for combination therapies to inform patient selection for future clinical trials. Methods: Patient-derived tissue microarrays and RNA-sequencing were employed to investigate ADORA3 expression. …”
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376
Synchrotron Radiation-Induced X-Ray Emission to Identify Metal Ions in Preparations of Purified Protein
Published 2002-01-01“…The suitability of synchrotron radiation-induced X-ray emission (SRIXE) for the detection and identification of metal ions in preparations of purified, soluble proteins was tested. …”
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377
Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Published 2017-04-01“…Long non-coding RNA microarray was applied to investigate the global long non-coding RNA expression profile in colorectal cancer. …”
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378
Identification of sero-reactive antigens for the early diagnosis of Johne's disease in cattle.
Published 2017-01-01“…JD has a high herd prevalence and causes serious animal health problems and significant economic loss in domesticated ruminants throughout the world. Since serological detection of MAP infected animals during the early stages of infection remains challenging due to the low sensitivity of extant assays, we screened 180 well-characterized serum samples using a whole proteome microarray from Mycobacterium tuberculosis (MTB), a close relative of MAP. …”
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379
Integrated analysis of hub genes and intrinsically disordered regions in triple-negative breast cancer
Published 2024-12-01“…Despite several attempts, the molecular pathways of TNBC remain unknown, posing a significant clinical barrier in the search for viable targets. Two microarray datasets were used to identify possible targets for TNBC, GSE38959 and GSE45827, retrieved from the Gene Expression Omnibus (GEO) database. …”
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380
Early diagnosis of acute myocardial infarction via hub genes identified by integrated weighted gene co-expression network analysis
Published 2025-08-01“…Diagnostic biomarkers were selected and identified using three machine learning algorithms. …”
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