Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

“…Austeja Butkute,1,2,* Evelina Kazlauske,3,4,* Agata Mlynska,1,4 Emile Peciukaityte,3 Vitalijus Karabanovas,3,4 Ricardas Rotomskis,3,5 Simona Steponkiene3 1Laboratory of Immunology, National Cancer Institute, Vilnius, Lithuania; 2Life Science Center, Vilnius University, Vilnius, Lithuania; 3Biomedical Physics Laboratory of National Cancer Institute, Vilnius, Lithuania; 4Department of Chemistry and Bioengineering, Vilnius Gediminas Technical University, Vilnius, Lithuania; 5Biophotonics Group of Laser Research Center, Vilnius University, Vilnius, Lithuania*These authors contributed equally to this workCorrespondence: Simona Steponkiene, Biomedical Physics Laboratory of National Cancer Institute Vilnius, Vilnius, Lithuania, Email simona.steponkiene@nvi.ltBackground: Photodynamic therapy (PDT) is a promising tool that utilizes photosensitizers (PS) for two functions: cancer imaging by fluorescence (diagnostics), and treatment by the generation of reactive oxygen species (therapy). …”
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GeoGraphRAG: A graph-based retrieval-augmented generation approach for empowering large language models in automated geospatial modeling by Jianyuan Liang, Shuyang Hou, Haoyue Jiao, Yaxian Qing, Anqi Zhao, Zhangxiao Shen, Longgang Xiang, Huayi Wu

“…Geospatial modeling aims to integrate multiple geospatial data sources and geoprocessing functions based on user application demands to address complex geospatial challenges. …”
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Visualization of four-dimensional X-ray absorption fine structure data using a virtual reality system by Haruo Igarashi, Daiki Kido, Yutaka Ishii, Yasuhiro Niwa, Atsushi Okamoto, Masao Kimura

“…X-ray spectromicroscopy is extensively utilized for nondestructive mapping of chemical states in materials. …”
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Resolving Turbulence Drivers in Two Luminous Obscured Quasars with JWST/NIRSpec Integral Field Unit by Mandy C. Chen, Hsiao-Wen Chen, Michael Rauch, Andrey Vayner, Weizhe Liu, David S. N. Rupke, Jenny E. Greene, Nadia L. Zakamska, Dominika Wylezalek, Guilin Liu, Sylvain Veilleux, Nicole P. H. Nesvadba, Caroline Bertemes

“…In this Letter, we investigate the turbulence and energy injection in the extended nebulae surrounding two luminous obscured quasars, WISEA J100211.29+013706.7 ( z = 1.5933) and SDSS J165202.64+172852.3 ( z = 2.9489). Utilizing high-resolution data from the NIRSpec integral field unit onboard the James Webb Space Telescope, we analyze the velocity fields of line-emitting gas in and around these quasars and construct the second-order velocity structure functions (VSFs) to quantify turbulent motions across different spatial scales. …”
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Microbial dark matter spearheading the biogeochemical cycle in the Solar Lake of Taba, Egypt by Rehab Z. Abdallah, Ali H.A. Elbehery, Amged Ouf, Rania Siam

“…Some non-methanogenic MAGs had the genetic capacity to utilize methanol and glycine-betaine as carbon sources. …”
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Implementation of a Smart Home Intruder Detection System using a Vibrometer and ESP 32 CAM by Samuel Owoeye, Folasade Durodola, Adekunle Oyelami, Racheal Oladejo, Samuel Obasuyi, Ademola Qasim, Joshua Ogundairo

“…The topic of security is quite important; hence this paper presents the development and implementation of a Smart Intruder Detection System utilizing the ESP32-CAM board, the Vibrometer and the ATMega328P microcontroller to enhance lighting, security, and surveillance functionalities. …”
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Integration of Daylight in Building Design as a Way to Improve the Energy Efficiency of Buildings by Adrian Trząski, Joanna Rucińska

“…According to the United Nations Environment Programme reports, buildings are responsible for nearly 40% of energy-related emissions; therefore, energy-optimized building design is crucial to reduce the reliance on non-renewable energy sources as well as greenhouse gas emissions. The OECD reports indicate the use of Building Information Modelling (BIM) as one of the effective strategies for decarbonization of buildings, since a 3D digital representation of both physical and functional characteristics of a building can help to design a more efficient infrastructure. …”
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Automated Recipe Generation AI Tool from Food Images using Machine Learning. Approach for Ingredient Extraction and Cooking Instructions by Lwamaza, Eddy, Nuwasiima, Happy

“…It outlines the systematic approach taken to analyze user needs, define functional and non-functional requirements, and develop a robust system architecture. …”
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The responses of vegetation water use efficiency to biomass density and CO2 balance in dryland of Central Asia during 21st century by Alphonse Kayiranga, Xi Chen, Xuexi Ma, Dative Ingabire, Tie Liu, Yaoming Li, Emeka Edwin Igboeli, Eldiiar Duulatov, Hubert Hirwa, Clement Nzabanita, Ping Hu

“…Water-use efficiency (WUE) is a critical component that links plant carbon (CO2) and water cycles through various aspects of plant ecosystem functioning. However, the variations of plant CO2 in response to water use efficiency (WUE) across temperate dryland ecosystems remains inadequately understood. …”
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Integrated Analysis of Single‐Cell and Bulk RNA‐Sequencing Defines N7‐Methylguanosine (m7G)‐Mediated Modifications' Role in Prognosis and the Tumor Immune Microenvironment in Hepat... by Jiahua Liang, Mingjian Ma, Borui Xu, Cheng Zhong, Guangyan Zeng, Huijiao Lu, Jiaming Lai, Jiancong Chen

“…Data pertaining to m7G‐related protein and mRNA levels were sourced from the Human Protein Atlas (HPA) database. …”
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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer by Tiankai Xu, Chu Chu, Shuyu Xue, Tongchao Jiang, Ying Wang, Wen Xia, Huanxin Lin

“…Additionally, we sourced genes associated with mitochondrial energy metabolism from GeneCards and extant literature. …”
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Identification of intratumoral bacteria that enhance breast tumor metastasis by Zachary J. Gerbec, Antonio Serapio-Palacios, Avril Metcalfe-Roach, Zakhar Krekhno, Haggai Bar-Yoseph, Sarah E. Woodward, Jorge Pena-Díaz, Oksana Nemirovsky, Shannon Awrey, Sebastian H. Moreno, Sean Beatty, Esther Kong, Nina Radisavljevic, Mihai Cirstea, Shawn Chafe, Paul C. McDonald, Sam Aparicio, B. Brett Finlay, Shoukat Dedhar

“…We also identified enrichment of specific bacterial functions, providing insight into possible sources of bacteria-driven increases in the metastatic potential of multiple cancer types.…”
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Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

“…Further analytical procedures involved functional enrichment analysis, evaluation of immune infiltration, and examination of the mutation landscape.PTGES3 was identified as a pivotal gene associated with lipid metabolism. …”
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Innovation and Risk Avoidance of Smart Library Services Based on Generative Artificial Intelligence by Jia LIU

“…The study draws on both theoretical and empirical sources, utilizing qualitative analysis to examine trends in the use of generative AI in different types of library services. …”
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Beyond access: assessing WASH service delivery models in healthcare facilities of North Mecha, Dera, and Farta, Ethiopia by Abireham Misganaw Ayalew

“…The service providers (HCFs), however, are neither aware of them nor fully comprehend them. Common water sources for healthcare facilities (HCFs) included shallow wells equipped with solar power and utility connections. …”
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Assessing Causality Between Plasma Brain‐Derived Neurotrophic Factor With Major Depression Disorder: A Bidirectional Mendelian Randomization Study by Ming Chen, Hao‐Zhang Huang, Yi‐Hui Liu, Qiang Li, Lin‐Yan Fu, Cai‐Lan Hou

“…In a subsequent phase, we analyzed MDD data from FinnGen (N = 448,069) with plasma BDNF data from three additional GWAS sources: UK Biobank (N = 33,924), deCODE (N = 35,353), and INTERVAL (N = 3301). …”
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Understanding Hip Pain Through Social Media: An Initial Overview of an International Web-Based Survey by John M. Gaddis, BS, Erika Shults, MS, Bretton Laboret, BS, Ryan Bialaszewski, BS, Katerina Wells, MD, MPH, Charles South, PhD, Joel E. Wells, MD, MPH

“…Conclusions: This study demonstrates the feasibility of utilizing social media for a comprehensive web-based survey to gather patient-reported outcomes from individuals with various sources of hip pain internationally.…”
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Above-mJ optical parametric chirped pulse amplifier at 3 μm for laser-driven coherent soft x-ray generation beyond the water window by Pritha Dey, Lutz Ehrentraut, Johannes Tümmler, Matthias Schnürer, Stefan Eisebitt

“…This technology has paved the path toward tabletop coherent soft x-ray (SXR) sources in recent years. Commercial availability of high-power Yb:YAG lasers as the pump lasers has enabled OPCPA to generate high-energy femtosecond mid-IR pulses at a high repetition rate. …”
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An Adiabatic-Expansion-Induced Perturbation Study on Gas–Aerosol Partitioning in Ambient Air—Formation of NH₄NO₃ and Microdroplet Nitrogen Fixation (2) by Yating Gao, Qinchu Fan, Yujiao Zhu, Hengqing Shen, Qi Yuan, Yang Gao, Huiwang Gao, Xiaohong Yao

“…However, the current observational data do not allow us to derive a functional relationship between the redox reaction rate and these parameters, nor to fully detail the underlying chemistry. …”
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Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke by Ahmet Alptekin, Mohammad B. Khan, Mahrima Parvin, Hasanul Chowdhury, Sawaiz Kashif, Fowzia A. Selina, Anika Bushra, Justin Kelleher, Santu Ghosh, Dylan Williams, Emily Blumling, Roxan Ara, Asamoah Bosomtwi, Joseph A. Frank, Krishnan M. Dhandapani, Ali S. Arbab

“…The objectives of the proposed studies were to determine whether LIPFUS-mediated increased delivery of EPC-derived exosomes enhances stroke recovery and functional improvement in mice with transient middle cerebral artery occlusion (tMCAo) stroke.MethodsTo enhance exosome delivery to the stroke area, we utilized LIPFUS. …”
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