Trade-off between resistance and persistence in high cell density cultures by F. Beulig, J. Bafna-Rührer, P. E. Jensen, S. H. Kim, A. Patel, V. Kandasamy, C. Steffen, K. Decker, D. Zielinski, L. Yang, E. Özdemir, S. Sudarsan, B. Palsson

“…We suggest that this trade-off explains observed growth arrests in high-density cultures and that it results from the disruption of cellular homeostasis, due to re-allocation of limited cellular resources from resistance functions toward increased maintenance requirements. …”
Get full text

PlastidHub: An integrated analysis platform for plastid phylogenomics and comparative genomics by Na-Na Zhang, Gregory W. Stull, Xue-Jie Zhang, Shou-Jin Fan, Ting-Shuang Yi, Xiao-Jian Qu

“…The plastid genome (plastome) represents an indispensable molecular resource for studying plant phylogeny and evolution. …”
Get full text

Fuzzy volume fraction model representation of blood-based sisko tri-hybrid nanofluid flow via a stretching cylinder by N. Deepa, P. Kavya, N. Thamaraikannan, S. Madhanraj, P. Asaigeethan, K. Loganathan

“…The triangular membership function (TMF) is utilized to analyze the variability of uncertainty, while the α− cut is responsible for controlling the TFNs. …”
Get full text

Sustainable and innovative project management strategies in the engineering management industry: Case study of Drees & Sommer by Wang Yufan

“…The study points out that the limitations of traditional management models urgently need to be innovated through intelligent technology, lean management, and digital tools such as BIM technology to optimize resource utilization and reduce environmental impact. …”
Get full text

Production capacity prediction of U-shaped horizontal wells for in-situ pyrolysis of tar-rich coal: Experimental and numerical simulation study by Zhen DONG, Yanpeng CHEN, Mengyuan ZHANG, Xinggang WANG, Lixin JIAO, Shuo FENG, Bo REN, Hao CHEN, Junjie XUE, Yufeng ZHAO, Diefang HUANG

“…Under the goal of “dual carbon”, “taking hydrogen and retaining carbon” has become an inevitable choice for the clean utilization of coal, and underground coal pyrolysis provides a new idea for increasing domestic tar and gas production. …”
Get full text

Life cycle assessment of an entirely wood floor system designed for carbon negativity, future adaptability, and end-of-life de/re/construction by Muzan Williams Ijeoma, Sovanroth Ou, Amin Nabati, Hao Chen, Michael Stoner, Patricia Layton, Dustin Albright, Brandon Ross, Weichiang Pang, Michael Carbajales-Dale

Get full text

Building and implementation of a common infrastructure for specimen and data storage at an academic medical center by Donna A. Santillan, Laura S. Jacobus, Michael D. Henry, George J. Weiner, Patricia L. Winokur, Boyd M. Knosp, Heath A. Davis

“…The software needed to function at an enterprise level while continuing to allow investigators the autonomy and security access they desire. …”
Get full text

Properties and computational insights of catalysts based on amide linked polymer for photo-Fenton remediation of Rhodamine B dye by Asmaa M Fahim, Khadiga Mohamed Abas

Get full text

O-GlcNAcylation of glutaminase isoform KGA inhibits ferroptosis through activation of glutaminolysis in hepatoblastoma by Sijia Fang, Guoqing Zhu, Yi Xie, Miao Ding, Ni Zhen, Jiabei Zhu, Siwei Mao, Xiaochen Tang, Han Wu, Qi Zhang, Aijia Zhang, Xin Ni, Qiuhui Pan, Ji Ma

“…The O-GlcNAcylation of KGA isoform ensures its stability and glutaminase function in HB cells, which can serve as a promising therapeutic target for KGA-mediated glutaminolysis in HB.…”
Get full text

Wild ActionFormer: Enhancing wildlife action recognition for 11 endangered species in Wolong by Dan Liu, Qianqian Sun, Jin Hou, Bochuan Zheng, Jindong Zhang, Desheng Li, Tomas Norton, Jifeng Ning

“…We constructed a differential dispersion regularization loss function to maintain the alignment of self-supervised learning features and improve the network’s robustness against interference. …”
Get full text

Genome-Wide Identification and Expression Analysis of the Mango (<i>Mangifera indica</i> L.) SWEET Gene Family by Lirong Zhou, Xinyu Liu, Xiangchi Leng, Meng Zhang, Zhuanying Yang, Wentian Xu, Songbiao Wang, Hongxia Wu, Qingzhi Liang

Get full text

Pixel-super-resolved lens-free quantitative phase microscopy with partially coherent illumination by Yang Chen, Xuejuan Wu, Linpeng Lu, Jiasong Sun, Runnan Zhang, Wenhui Lin, Yufan Chen, Maciej Trusiak, Peng Gao, Chao Zuo

“…Based on the partially coherent imaging model, we integrate the spatial coherence transfer function (SCTF) obtained from the pre-calibrated LED source distribution during the iteration process to obtain an accurate high-resolution recovery. …”
Get full text

High-quality bonds: serine acetyltransferase 2 gene revealed by GWAS is associated with grain protein content in spring durum wheat by Aleksey Ermolaev, Ludmila Bespalova, Varvara Korobkova, Aleksey Yanovsky, Lubov Nazarova, Aleksandra Kroupina, Anastasia Chernook, Aleksandra Mudrova, Viktoria Voronezhskaya, Viktoria Voronezhskaya, Pavel Kroupin, Gennady Karlov, Mikhail Divashuk, Mikhail Divashuk

“…This study provides actionable genetic resources for breeding high-protein spring durum wheat genotypes.…”
Get full text

Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
Get full text

The Multifunctional Catalytic Hemoglobin from <i>Amphitrite ornata</i>: Protocols on Isolation, Taxonomic Identification, Protein Extraction, Purification, and Characterization by Anna L. Husted, Victoria R. Sutton, Lauren A. Presnar, R. Kevin Blackburn, Joseph L. Staton, Stephen A. Borgianini, Edward L. D’Antonio

“…The multifunctional catalytic hemoglobin from the terebellid polychaete <i>Amphitrite ornata</i>, also named dehaloperoxidase (<i>Ao</i>DHP), utilizes the typical oxygen transport function in addition to four observed activities involved in substrate oxidation. …”
Get full text

Intrapleural tissue plasminogen activator and deoxyribonuclease in complex pleural effusion and empyema, clinical outcomes, and predictors by Yub Raj Sedhai, Priyanka Bhat, Roshan Acharya, Nada Qaisar Qureshi, Fawaz Mohammed, Irfan Waheed, Tahir Muhammad Abdullah Khan, Muhammad Altaf Ahmed, Nisarfathima Kazimuddin, Akinchan Kafle, Rodney T. Steff, Karan Singh

“…We have tested the clinical role RAPID score (Renal function measured as urea, Age, fluid Purulence, Infection source, Dietary status measured as albumin) to predict treatment success, and all-cause mortality at 6 months. …”
Get full text

Metagenomic and phylogenetic analyses reveal gene-level selection constrained by bacterial phylogeny, surrounding oxalate metabolism in the gut microbiota by Sromona D. Mukherjee, Mangesh Suryavanshi, John Knight, Dirk Lange, Aaron W. Miller

“…The frc gene was primarily allocated to the Pseudomonodota phylum, particularly the Bradyrhizobium genus, which is a species capable of utilizing oxalate as a sole carbon and energy source. …”
Get full text

Integrating geographic information systems into veterinary education within the one health framework: an interdisciplinary approach by Antonio Contreras, Víctor Cuevas, Jorge Rivera-Gomis, Jorge Rivera-Gomis, Antonio Sánchez, Pelayo Acevedo, Joaquin Vicente

“…Using open-access tools, we designed a series of tutorials, manuals, and exercises with graduated levels of complexity. These resources were based on real and simulated epidemiological datasets and focused on topics relevant to animal and public health. …”
Get full text

Two-stage strategic optimal planning of distributed generators and energy storage systems considering demand response program and network reconfiguration by Saleh Ba-swaimi, Renuga Verayiah, Vigna K. Ramachandaramurthy, Ahmad K. ALAhmad, Sanjeevikumar Padmanaban

“…Simulation outcomes from various case studies indicate that incorporating optimal DRP and NR scheduling into a hybrid system of RESs and BESSs enhances renewable energy penetration by 17.39% compared to the case utilizing just BESSs. Moreover, the established model, featuring a wind-DG/PV-DG/BESS/DRP/NR configuration, achieves significant improvements in all objective functions, including a 31.14% reduction in total system cost, a 61.67% decrease in power loss, and a 58.11% improvement in voltage deviation, compared to the base case.…”
Get full text

PA-Win2: In Silico-Based Discovery of a Novel Peptide with Dual Antibacterial and Anti-Biofilm Activity by Jin Wook Oh, Min Kyoung Shin, Hye-Ran Park, Sejun Kim, Byungjo Lee, Jung Sun Yoo, Won-Jae Chi, Jung-Suk Sung

Get full text