A multi-omics Mendelian randomization identifies putatively causal genes and DNA methylation sites for asthma by Jia Wang, MD, Jinxin Hu, MS, Dan Qin, MD, Dan Han, MD, Jiapeng Hu, MD

“…Employing Summary Data-based Mendelian Randomization (SMR) and Two-Sample Mendelian Randomization (TSMR), we pinpointed asthma causal genes, causal DNA methylation sites, and methylation sites affecting gene expression, cross validated with at least 2 large-scale GWAS from each source. We utilized colocalization for genetic associations, meta-analysis for data integration, two-step MR for methylation-gene-asthma mediation mechanism. …”
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How does soil carbon sequestration affect greenhouse gas emissions from a sheep farming system? Results of an life cycle assessment case study by Pasquale Arca, Enrico Vagnoni, Pierpaolo Duce, Antonello Franca

“… • Extensification of dairy sheep systems determines lower environmental impact per hectare of utilized agricultural area. • Enteric methane emissions are the main source of GHG emissions of the sheep milk life cycle…”
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Accelerated Real-Time Simulations for Testing a Reactive Power Flow Controller in Long-Term Case Studies by Katja H. Sirviö, Mike Mekkanen, Kimmo Kauhaniemi, Hannu Laaksonen, Ari Salo, Felipe Castro, Davood Babazadeh

“…The platform is planned to be utilized in the development and testing of active network management functions for microgrids and smart grids. …”
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Bifurcation and controller design in a 3D delayed predator-prey model by Jinting Lin, Changjin Xu, Yiya Xu, Yingyan Zhao, Yicheng Pang, Zixin Liu, Jianwei Shen

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Designing CITOBOT: A portable device for cervical cancer screening using human-centered design, smart prototyping, and artificial intelligence by Marcela Arrivillaga, Paula C. Bermúdez, Juan Pablo García-Cifuentes, Hernán Darío Vargas-Cardona, Daniela Neira, Maria del Mar Torres, Mérida Rodríguez-López, Daniela Morales, Bleider Arizala

“…Feedback was crucial in assessing and refining the device's functionality, focusing on capturing high-quality cervical images. …”
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Research Progress of Lycium ruthenicum Based on CiteSpace by Fei LIU, Lutao ZHANG, Jia MI, Lu LU, Bo JIN, Yingping LI, Guoli DAI, Linyuan DUAN, Yamei YAN

“…Lycium ruthenicum, a plant resource rich in health-active ingredients such as acylated petunidin anthocyanins, is increasingly receiving attention. …”
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A TRIM Family-Based Strategy for TRIMCIV Target Prediction in a Pan-Cancer Context with Multi-Omics Data and Protein Docking Integration by Yisha Huang, Jiajia Xuan, Jiayan Liang, Xixi Liu, Yonglei Luo, Xuejuan Gao, Wanting Liu

“…TRIMCIVtargeter not only provides a cancer-related resource for studying TRIMCIV-mediated regulatory mechanisms but also offers a new perspective for family-specific PPI prediction, holding significant implications for biomarker discovery and therapeutic targeting in oncology. …”
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Human cancer-targeted immunity via transgenic hematopoietic stem cell progeny by Theodore S. Nowicki, Nataly Naser Al Deen, Cole W. Peters, Begoña Comin-Anduix, Egmidio Medina, Cristina Puig-Saus, Ignacio Baselga Carretero, Paula Kaplan-Lefko, Mignonette H. Macabali, Ivan Perez Garcilazo, Daniel Chen, Jia Pang, Beata Berent-Maoz, Salem Haile, Jonathan Rodriguez, Moe Kawakami, Conner K. Kidd, Ameya Champhekar, Giuseppe Carlucci, Agustin Vega-Crespo, Bartosz Chmielowski, Arun Singh, Noah Federman, Gary M. Schiller, Sarah J. Larson, Martin Allen-Auerbach, Alexandra M. Klomhaus, Jerome Zack, David Baltimore, Lili Yang, Donald B. Kohn, Owen N. Witte, Antoni Ribas

“…These results demonstrate the utility of transgenic HSCs to generate a self-renewing source of tumor-specific cellular immunotherapy in human participants. …”
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MOG35 − 55-induced EAE model of optic nerve inflammation compared to MS, MOGAD and NMOSD related subtypes of human optic neuritis by Erin N. Capper, Edward F. Linton, Jeffrey J. Anders, Randy H. Kardon, Oliver W. Gramlich

“…Given its association with visual impairment and varying extent of visual recovery, ON has been recognized as a significant health burden with a need for new therapeutic strategies to improve long-term visual outcomes. Among the resources utilized to study ON, animal models have emerged as powerful tools to examine the underlying pathophysiology and the effectiveness of proposed therapies. …”
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Inverse Analysis of Thermal Parameters of Arch Dam Concrete Based on Walrus Optimization Algorithm by Youle Wang, Zhengjian Miao, Rui Song, Junchi Zhou, Yuheng Pan, Feng Wang

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Cellulose Nanofibril-Based Triboelectric Nanogenerators Enhanced by Isoreticular Metal-Organic Frameworks for Long-Term Motion Monitoring by Mingli Shang, Yan Zong, Xiujun Zhang

“…Cellulose nanofibril (CNF) is a sort of novel nanomaterial directly extracted from plant resources, inheriting the advantages of cellulose as a cheap, green and renewable material for the development of new-generation eco-friendly electronics. …”
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Application of deep learning for diagnosis of shoulder diseases in older adults: a narrative review by Sung Min Rhee

“…Shoulder diseases pose a significant health challenge for older adults, often causing pain, functional decline, and decreased independence. This narrative review explores how deep learning (DL) can address diagnostic challenges by automating tasks such as image segmentation, disease detection, and motion analysis. …”
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Identity-Based Provable Data Possession with Designated Verifier from Lattices for Cloud Computing by Mengdi Zhao, Huiyan Chen

“…In contrast, private verification restricts the auditing capability to the data owner, providing better privacy protection but often resulting in higher verification costs and operational complexity due to limited local resources. Moreover, most existing PDP schemes are based on classical number-theoretic assumptions, making them vulnerable to quantum attacks. …”
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Organizational citizenship behaviour relationship on challenge stress, hindrance stress and turnover intention in hotel industry employees in Java island by Kumala Hasta Prasetio, Hidajat Hendarsjah

“…A quantitative approach was utilized, involving 220 hotel employees from various regions in Java. …”
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SPC25 as a prognostic and immune-related biomarker in lung adenocarcinoma by Pan Liu, Lili Wang, Sining Xing, Song Zhao, Huiying Yu

“…SPC25 has a significant role in the occurrence and development of malignant tumors, but its role in lung adenocarcinoma has not been established. This study utilizes the TCGA database and centrosome assembly checkpoint specialized resources to explore the molecular mechanisms of lung adenocarcinoma and its interaction with the immune system. …”
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An Adiabatic-Expansion-Induced Perturbation Study on Gas–Aerosol Partitioning in Ambient Air—Formation of NH₄NO₃ and Microdroplet Nitrogen Fixation (2) by Yating Gao, Qinchu Fan, Yujiao Zhu, Hengqing Shen, Qi Yuan, Yang Gao, Huiwang Gao, Xiaohong Yao

“…Recent observations have increasingly challenged the conventional understanding of atmospheric NH₃ and its potential sources in remote environments. Laboratory studies suggest that the microdroplet redox generation of NH₃ could offer an alternative explanation. …”
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Microwave-assisted extraction of essential oils from basil leaves (Ocimum basilicum L.) and coriander seeds (Coriandrum sativum L.): A comparative study on chemical composition, an... by G.M. Masud Rana, Subarna Sandhani Dey, Bijoy Chandra Ghos, Md. Jasim Uddin, Tahmina Akter Chowdhury, Md. Tariqul Islam, Toufikur Rahman, Md. Jobayear Hossain, Jaytirmoy Barmon, Mst. Sarmina Yeasmin

“…Essential oils (EOs), known for their aromatic and bioactive properties, are widely utilized in the cosmetic and food industries. Microwave-assisted extraction (MAE) has emerged as a green, efficient and rapid technique for extracting EOs from plant sources. …”
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Research on Stacking Distribution of Steel Plates Input Based on Improved Multi-objective Particle Swarm Optimization by ZHONG Chuanjie, CHENG Wenming, DU Run, GAO Xuchao, ZHANG Lin

“…The inventory balance index was established based on the standard deviation of the number of steel plates allocated to each reservoir to fully mobilize and balance material storage resources during operation. These three indices were utilized to evaluate the degree of stack allocation and served as the objective function to establish a multi-objective decision optimization model for the stack allocation problem of steel plates. …”
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Barcoded Hybrids of Extracellular Vesicles and Lipid Nanoparticles for Multiplexed Analysis of Tissue Distribution by Alena Ivanova, Renata Chalupska, Ana Filipa Louro, Mike Firth, Hernán González‐King Garibotti, Leif Hultin, Franziska Kohl, Elisa Lázaro‐Ibáñez, Julia Lindgren, Gentian Musa, Erik Oude Blenke, Andreia M. Silva, Louis Szeponik, Agnes Taylor, Ida Viken, Xiaoqin Wang, Karin Jennbacken, John Wiseman, Niek Dekker

“…To examine this possibility further, it is shown that HAP1 hEV loaded with Cre mRNA displayed functional delivery to the lungs. Overall, the barcoded hEV technology enables rapid profiling of biodistribution across EV cell sources, which is poised to improve throughput and extent of EV studies, while reducing the number of animals required for research.…”
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Tensile Resistance and Fracture Mechanisms of Silica Aerogels Reinforced by Nanotube–Graphene Hybrid Networks by Lin Guo, Mu Du, Jiaqian Li, Wei Li, Mingyang Yang, Gongming Xin

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