O-GlcNAcylation of glutaminase isoform KGA inhibits ferroptosis through activation of glutaminolysis in hepatoblastoma by Sijia Fang, Guoqing Zhu, Yi Xie, Miao Ding, Ni Zhen, Jiabei Zhu, Siwei Mao, Xiaochen Tang, Han Wu, Qi Zhang, Aijia Zhang, Xin Ni, Qiuhui Pan, Ji Ma

“…The O-GlcNAcylation of KGA isoform ensures its stability and glutaminase function in HB cells, which can serve as a promising therapeutic target for KGA-mediated glutaminolysis in HB.…”
Get full text

A Refined Terrace Extraction Method Based on a Local Optimization Model Using GF-2 Images by Guobin Kan, Jie Gong, Bao Wang, Xia Li, Jing Shi, Yutao Ma, Wei Wei, Jun Zhang

“…Finally, we utilized multi-source RS data along with terrain elements for correction and optimization to generate a 1 m resolution terrace distribution map in the Zuli River Basin (TDZRB). …”
Get full text

Alaska Upper Crustal Velocities Revealed by Air-to-Ground Coupled Waves From the 2022 Hunga Tonga-Hunga Ha’apai Eruption by Kenneth Macpherson, David Fee, Stefan Awender, Bryant Chow, Juliann Colwell, Sam Delamere, Matt Haney

“…This type of air-to-ground coupled wave was observed globally following the largest explosion of the instrumental age, the climactic eruption of the Hunga Tonga-Hunga Ha’apai volcano on 15th January, 2022. We utilize this unprecedented source, along with the presence of colocated seismometers, infrasound sensors, and barometers in Alaska, to examine coupling and reveal elastic parameters beneath the stations. …”
Get full text

T cell-related diagnostic model and the underlying mechanism related to PRF1-mediated glycolysis in sepsis: evidences from single-cell, bulk transcriptomics, and experiment validat... by Fu Tian, Hui Chen, Zhicheng Huang, Kai Qiu

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used for the function and pathways enrichment analysis. Metabolic flux analysis was performed to investigate the underlying metabolic mechanism. …”
Get full text

ML-Based Screening of miRNA Inhibitors and Intervention of lncRNA/miRNA/mRNA Axis in Oncogenic KRAS-Associated Colorectal Cancer by Prasanna Srinivasan Ramalingam, Deepak B. Thimiri Govinda Raj, Murugan Subramanian, Sivakumar Arumugam

“…Although the role and function of the lncRNA axis are not clearly understood, various studies have recently focussed on the evaluation of the lncRNA axis role in various cancers. …”
Get full text

FAM3C Regulates Glioma Cell Proliferation, Invasion, Apoptosis, and Epithelial Mesenchymal Transition via the Notch Pathway by Xiaochao Xia, Zihao Wang, Lvmeng Song, Yinchuan Cheng, Ping Xiong, Shun Li

“…Herein, we aimed to further investigate the oncological mechanism of FAM3C, specifically in glioma. Methods We utilized open‐source bioinformatics tools and platforms to analyze the transcriptional expression levels, prognosis, and correlation with clinical variables of FAM3C in gliomas, and subsequently, to hypothesize its potential molecular functions and possibly associated signaling pathways. …”
Get full text

Development of empirical correlations for sustainable breakup characterization of water and high-viscous oil sheets under acoustic perturbations using high-speed imaging by Aman Singh, Devesh T, Subhash K, Preetam Polavarapu, Jayakrishnan Rahul, Karthick S, Balaji K

“…The key innovation of this study is the design and fabrication of a compact liquid sheet acoustic atomizer that efficiently utilizes acoustic energy to produce high-quality sprays. …”
Get full text

Impulse Shaping Method Based on Bayesian Deconvolution by JIA Tonghui, LIU Yi, WANG Ming, MA Yingjie, WANG Bo

“…The initial step of this method entailed expressing the measured pulse signal as the convolution of the current impulse pulse signal and the detection system response function. Then, the measured signal was expressed in the continuous time domain and decomposed into the form of an impulse signal and a double exponential kernel convolution by derivation. …”
Get full text

Comparative energy metabolism in red and white muscles of juvenile yellowfin tuna, Thunnus albacore by Zhiyuan Lu, Zhiyuan Lu, Qian Li, Edwine Yongo, Juan Xiao, Zhiqiang Guo, Zhiqiang Guo

Get full text

Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke by Ahmet Alptekin, Mohammad B. Khan, Mahrima Parvin, Hasanul Chowdhury, Sawaiz Kashif, Fowzia A. Selina, Anika Bushra, Justin Kelleher, Santu Ghosh, Dylan Williams, Emily Blumling, Roxan Ara, Asamoah Bosomtwi, Joseph A. Frank, Krishnan M. Dhandapani, Ali S. Arbab

“…The objectives of the proposed studies were to determine whether LIPFUS-mediated increased delivery of EPC-derived exosomes enhances stroke recovery and functional improvement in mice with transient middle cerebral artery occlusion (tMCAo) stroke.MethodsTo enhance exosome delivery to the stroke area, we utilized LIPFUS. …”
Get full text

Nitrogen inputs suppress plant diversity by overriding consumer control by Xiaofei Li, Dean E. Pearson, Yvette K. Ortega, Lin Jiang, Shaopeng Wang, Qiang Gao, Deli Wang, Yann Hautier, Zhiwei Zhong

Get full text

Fuzzy volume fraction model representation of blood-based sisko tri-hybrid nanofluid flow via a stretching cylinder by N. Deepa, P. Kavya, N. Thamaraikannan, S. Madhanraj, P. Asaigeethan, K. Loganathan

“…The triangular membership function (TMF) is utilized to analyze the variability of uncertainty, while the α− cut is responsible for controlling the TFNs. …”
Get full text

Jacobian-Free Newton Krylov Methods for Steady and Transient Neutron Transport Models by ZHANG Yangyi, ZHANG Tiancheng, ZHOU Xiafeng

“…To rapidly construct the unified JFNK residuals, the parallel KBA transport sweep methods and physics-based preconditioning techniques were utilized to improve the computational efficiency. To rapidly construct the unified JFNK residuals, the parallel KBA transport sweep methods and physics-based preconditioning techniques were utilized. …”

Design and Evaluation of Real-Time Data Storage and Signal Processing in a Long-Range Distributed Acoustic Sensing (DAS) Using Cloud-Based Services by Abdusomad Nur, Yonas Muanenda

“…We employ the DynamoDB functionality of Amazon Web Services (AWS), which allows highly expandable storage capacity with latency of access of a few tens of milliseconds. …”
Get full text

Multi-objective Optimal Scheduling of Water-Carbon in Cascade Reservoirs during Impoundment for Carbon Emission Reduction by ZHOU Yan-lai, NING Zhi-hao, HE Jun-tao

“…[Conclusions] This study develops a multi-objective scheduling model for cascade reservoirs during the impoundment period and analyzes the nonlinear synergy and competitive relationships between carbon emissions and traditional water resource utilization benefits. The NSGA-Ⅱ optimization solutions significantly improv the long-term average power generation and storage rate while reducing greenhouse gas emissions without compromising flood control standards. …”
Get full text

Wild ActionFormer: Enhancing wildlife action recognition for 11 endangered species in Wolong by Dan Liu, Qianqian Sun, Jin Hou, Bochuan Zheng, Jindong Zhang, Desheng Li, Tomas Norton, Jifeng Ning

“…We constructed a differential dispersion regularization loss function to maintain the alignment of self-supervised learning features and improve the network’s robustness against interference. …”
Get full text

Design, Synthesis, and Antitumor Biological Evaluation of Galaxamide and Its Analogs by Yanyan Guo, Huixia Fan, Zhiqiang Luo, Jian Yang, Guodu Liu

Get full text

Structural optimization and performance evaluation of a sugarcane leaf mulching machine by Weihua Huang, Shuo Wang, Chang Ge, Lijiao Wei, Dongjie Du, Zhaojun Niu, Ming Li, Zhenhui Zheng

“…This study provides a valuable reference for advancing sugarcane leaf mulching machine performance and offers insights into more effective utilization of sugarcane leaf resources.…”
Get full text

Optimization of fermentation process of passion fruit-roselle complex fruit wine with immobilized yeast by ZHANG Xueling, YANG Qian, YANG Min, GUAN Chunhua, WANG Zilin, TAO Liang, TIAN Yang

Get full text

Synthesis of 0.75Pb(Zr_0.52Ti_0.48)O₃-0.25BiFeO₃ Thin Film Capacitors with Excellent Efficiency and Thermal Stability by Li Wu, Feifei Han, Kaiyuan Chen, Jianming Deng, Laijun Liu, Biaolin Peng

Get full text