Integration of multi-omics quantitative trait loci evidence reveals novel susceptibility genes for Alzheimer’s disease by Jinyang Gao, Xiaochan Bi, Wenjing Jiang, Yanqing Wang

“…By identifying multiple candidate targets and regulatory axes, our findings offer a valuable resource for prioritizing genes for functional validation and advancing future therapeutic development.…”
Get full text

Characteristic Fingerprint Based on Low Polar Constituents for Discrimination of Wolfiporia extensa according to Geographical Origin Using UV Spectroscopy and Chemometrics Methods by Yan Li, Ji Zhang, Yanli Zhao, Zhimin Li, Tao Li, Yuanzhong Wang

Get full text

Olive pomace lignin as a sustainable bio-based modifier for asphalt: performance, economic, and environmental evaluation by Ala Alobeidyeen, Amal Al-Hanaktah, Amani Abdallah Assolie

“…Abstract The pressing challenges of environmental pollution and the depletion of fossil resources have intensified the search for renewable and sustainable materials in the pavement industry. …”
Get full text

Phytobacter sp. RSE02 is a rice seed endophytic plant probiotic bacterium with human probiotic features and cholesterol-lowering ability by Santosh Kumar Jana, Rajarshi Bhattacharya, Sunanda Mukherjee, Samudra Gupta, Subhra Prakash Hui, Ansuman Chattopadhyay, Swadesh Ranjan Biswas, Sukhendu Mandal

“…We examine the safety and probiotic potential of RSE02 in human cell lines, zebrafish, and mice. Notably, RSE02 can utilize cholesterol as its sole carbon source; however, it does not adhere to the Caco-2 cell line or the zebrafish gut. …”
Get full text

Physical activity coaching for adults with mobility limitations: protocol for the ComeBACK pragmatic hybrid effectiveness-implementation type 1 randomised controlled trial by Kirsten Howard, Anne Tiedemann, Catherine Sherrington, Tammy Hoffmann, Kim L Bennell, Colin Greaves, Rana S Hinman, Nicholas F Taylor, Andrew Milat, Marina Pinheiro, Leanne Hassett, Maria Crotty, Lisa Harvey, Daniel Treacy, Matthew Jennings, Maayken van den Berg, Siobhan Wong, Catherine Kirkham, Elizabeth Ramsay, Sandra O'Rourke

“…It aims to estimate the effects on physical activity of: (1) an enhanced 6-month intervention package (one face-to-face physiotherapy assessment, tailored physical activity plan, physical activity phone coaching from a physiotherapist, informational/motivational resources and activity monitors) compared with a less intensive 6-month intervention package (single session of tailored phone advice from a physiotherapist, tailored physical activity plan, unidirectional text messages, informational/motivational resources); (2) the enhanced intervention package compared with no intervention (6-month waiting list control group); and (3) the less intensive intervention package compared with no intervention (waiting list control group). …”
Get full text

Proteomic profiling of the human amniotic stem cell-highly abundant secreted proteins by Dan He, Yuqiang Cheng, Hongkai Lv, Anqi Geng, Jie Zheng, Lin Dang, Pengfei Li

“…In this study, the expression profiles of secreted proteins from AMSCs and AECs were comprehensively analyzed utilizing mass spectrometry-based proteomics. The 71 highly abundant proteins and their potential biological functions were further investigated. …”
Get full text

Digital Governance Policy Implementation Model Through Electronification of Land and Building Acquisition Fees (E-BPHTB) at the Baubau City Regional Revenue Agency by Rahmawati Rahmawati

“…The results of the study indicate that the implementation of the Electronic policy (Land and Building Acquisition Fee) at Bapenda Baubau City is quite good, but not as expected: Organization in terms of budgeting, and methods are good but the human resources owned are still lacking, not adequate especially in the field of determination in the process of completing duties and functions. …”
Get full text

Development of a warning model for drug-induced liver injury in the older patients by Qiaozhi Hu, Qiaozhi Hu, Xiaoqi Li, Xiaoqi Li, Dan Zou, Zhiyao He, Zhiyao He, Ting Xu

Get full text

A Digital Software Support Platform for Hyperthyroidism Management in South Korea: Markov Simulation Model-Based Cost-Effectiveness Analysis by Jung Hyun Kim, Jaeyong Shin, Man S Kim, Jae Hoon Moon

“… Abstract BackgroundThe integration of wearable technology for heart rate monitoring offers potential advancements in managing hyperthyroidism by providing a feasible way to track thyroid function. Although digital health solutions are gaining traction in various chronic conditions, their cost-effectiveness in hyperthyroidism management requires deeper investigation. …”
Get full text

In Vitro Osteogenic Potential of Green Fluorescent Protein Labelled Human Embryonic Stem Cell-Derived Osteoprogenitors by Intekhab Islam, Gopu Sriram, Mingming Li, Yu Zou, Lulu Li, Harish K. Handral, Vinicus Rosa, Tong Cao

“…Human embryonic stem cells (hESCs) are potentially an unlimited source of healthy and functional osteoprogenitors (OPs) that could be utilized for bone regenerative applications. …”
Get full text

DFT-guided synthesis of N, B dual-doped porous carbon from saccharina japonica for enhanced oxygen reduction catalysis by Junjie Zhang, Chao Wu, Jilong Wang, Maosong Xia, Shixin Li, Long Liu, Wuguo Wei, Xing Peng

“…This work not only extends the range of ORR catalysts derived from biomass but also provides guidance on creating and producing affordable, effective catalysts that utilize natural resources.…”
Get full text

Unlocking Pinus ponderosa (Douglas ex C. Lawson) potential: a comprehensive review of results from native and introduced areas by Karol Tomczak, Karol Tomczak, Karol Tomczak, Zdeněk Vacek, Jan Cukor, Jan Cukor, Stanislav Vacek, Václav Bažant, Aleš Zeidler, Václav Trojan, Josef Gallo, Jakub Černý

“…We reviewed 229 research sources to analyze P. ponderosa’s potential for utilization in new areas. …”
Get full text

Harnessing evanescent photoacoustic waves for multi-domain imaging by Rong Zhou, Liying Zhang, Beibei Li, Jingtao Xiao, Yiheng Xing, Chang Chen, Yuecheng Shen, Hao Shen, Deng Pan, Hongxing Xu

“…Leveraging these features, we develop a proof-of-concept for supercritical angle photoacoustic microscopy (SA-PAM), which utilizes evanescent PA waves to enable new PAM functionalities, such as surface topography reconstruction and edge detection. …”
Get full text

Effects of Material Rheology and Die Walls Translational Motions on the Dynamics of Viscous Flow during Equal Channel Angular Extrusion through a Segal 2θ-Die: CFD 2D Solution of a... by Alexander V. Perig, Nikolai N. Golodenko

Get full text

Multi-Timescale Nested Hydropower Station Optimization Scheduling Based on the Migrating Particle Whale Optimization Algorithm by Mi Zhang, Guosheng Zhou, Bei Liu, Dajun Huang, Hao Yu, Li Mo

“…Exploring efficient and stable solution methods for hydropower generation optimization models is crucial for enhancing reservoir power generation efficiency and achieving the sustainable use of water resources. However, existing studies predominantly focus on single-timescale scheduling models, failing to fully exploit multi-timescale runoff information. …”
Get full text

Japanese Family Conditions Demonstrating Family Resilience: Directed Content Analysis Based on Literature and Family Interviews by Naohiro Hohashi, Natsumi Kijima

“…<b>Conclusions:</b> From these, a variety of diverse aspects contributing to a family’s resilience, including family member interactions, entire family interactions, use of social resources, and religious and spiritual support, were indicated.…”
Get full text

The biodegradation of low-density polyethylene by Bacillus species by Felicia E. Uwakwe, Tobias I.N. Ezejiofor, Ernest A.A. Anyalogbu, Toochukwu E. Ogbulie

“…The observations showed that these Bacillus spp. indigenous to Owerri Metropolis have the ability to degrade PE and utilize it as a carbon source, and it was concluded that biodegradation was achieved, and that PE which was regarded to be inert can be biodegraded when exposed to the right microorganisms.…”
Get full text

Exploring the Acceptance and Application of a Humanoid Robot: Insights from Three Field Studies

“…In culture, the robot primarily served as an information provider, whereas in daycare, it was most effective as a source of entertainment. Although participants found the robot intuitive and engaging, its limited perceived usefulness highlights the need for enhanced interactivity and functionality to maximize its economic and operational potential in addressing skilled labour shortages. …”
Get full text

Preparation and stability of angiotensin-I-converting enzyme (ACE) inhibitory peptides from protein hydrolysate of Wuyi rock tea residues by Xiaoliang Cao, Huiyuan Zhou, Jindong Xie, Linxia Huang, Songbin Guo, Zexiao Zhang, Qun Chen, Chun Meng, Feng Zhang, Jing Hong

“…These peptides could be utilized in the development of nutraceuticals, functional foods, and pharmaceuticals.…”
Get full text

Effects of enhanced fermentation with high-yielding strains of Tetramethylpyrazine on flavor quality of Douchiba by Panpan Yang, Qin Wang, Yurou Yang, Anyan Wen, Haiying Zeng, Na Liu, Likang Qin

Get full text