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Effects of oxidized phospholipids on gene expression in RAW 264.7 macrophages: a microarray study.
Published 2014-01-01“…In this study we present the effects of 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC) and 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) on gene expression in RAW 264.7 macrophages using cDNA microarrays. …”
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Microarray analysis of the effects of Acthar Gel versus methylprednisolone in a model of focal segmental glomerulosclerosis in female rats
Published 2025-04-01“…On Day 56, animals were sacrificed, and RNA samples of kidney cortex tissue were analyzed using microarrays. Compared with control, Acthar significantly decreased the expression of more genes related to inflammation, immune function, and fibrosis than MP. …”
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Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes
Published 2001-02-01“…Our method provides a cost-effective alternative to conventional attachment strategies that is particularly suitable for genotyping PCR products with nucleic acid microarrays.…”
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Fast Spot Locating for Low-Density DNA Microarray
Published 2025-03-01“…Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. …”
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Phenotype microarray-based assessment of metabolic variability in plant protoplasts
Published 2025-05-01“…Conclusions The standardized high-throughput system developed was effective for the metabolic characterization of plant protoplasts. …”
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Inflammatory Pathways in Parkinson’s Disease; A BNE Microarray Study
Published 2012-01-01“…The main focus of PD research is to better understand substantia nigra homeostasis disruption, particularly in relation to the wide-spread deposition of the aberrant protein α-synuclein. Microarray technology contributed towards PD research with several studies to date and one gene, ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1), consistently reappeared across studies including the present study, highlighting dopamine (DA) metabolism dysfunction resulting in oxidative stress and most probably leading to neuronal cell death. …”
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Implementation of NGS and SNP microarrays in routine forensic practice: opportunities and barriers
Published 2025-05-01“…NGS enables STR sequencing and SNP typing with enhanced discriminatory power, better performance with degraded DNA, and improved mixture deconvolution. Conversely, SNP microarrays offer a cost-effective solution for extended kinship testing, Forensic Investigative Genetic Genealogy (FIGG), and phenotypic prediction, though they are less effective with low-quality samples and DNA mixtures. …”
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Optimization based tumor classification from microarray gene expression data.
Published 2011-02-01“…<h4>Background</h4>An important use of data obtained from microarray measurements is the classification of tumor types with respect to genes that are either up or down regulated in specific cancer types. …”
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Microarray integrated spatial transcriptomics (MIST) for affordable and robust digital pathology
Published 2024-11-01“…To address these issues, we propose Microarray Integrated Spatial Transcriptomics (MIST), combining conventional tissue microarray (TMA) with Visium, using laser-cutting and 3D printing to enhance slide throughput. …”
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Gene expression analysis of ABC transporter family in breast tumors: relationship with chemotherapy effect and disease prognosis
Published 2020-09-01“…RNA was isolated from paired samples of tumor tissue before and after NAC. A microarray study of all tumor samples was performed on ClariomТМ S Assay, human microarrays. …”
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A Meta‐Analysis of the Effects of Early Life Stress on the Prefrontal Cortex Transcriptome Reveals Long‐Term Downregulation of Myelin‐Related Gene Expression
Published 2025-06-01“…For each gene, a random‐effects meta‐analysis model was then fit to the ELS versus control effect sizes (Log2 Fold Changes) from each study. …”
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A review of independent component analysis application to microarray gene expression data
Published 2008-11-01“…Independent component analysis (ICA) methods have received growing attention as effective data-mining tools for microarray gene expression data. …”
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Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray.
Published 2010-07-01“…Understanding the complex interactions between the host's immune system and bacterial pathogens is central to the field of infectious diseases and to the development of effective diagnostics and vaccines.<h4>Methodology</h4>We report the development of a microarray comprised of proteins expressed from 96% (1433/1493) of the predicted ORFs encoded by the genome of the zoonotic pathogen Bartonella henselae. …”
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Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
Published 2011-01-01“…The microarray evidences of molecular basis of obesity and insulin resistance are presented here. …”
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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
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Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing
Published 2025-07-01“…Abstract Background Chromosomal microarray analysis (CMA) is being increasingly used to reveal the genetic causes of miscarriage. …”
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