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Effective detection of 148 cases chromosomal mosaicism by karyotyping, chromosomal microarray analysis and QF-PCR in 32,967 prenatal diagnoses
Published 2025-04-01“…Methods A total of 148 fetuses diagnosed with chromosomal mosaicism by karyotyping with copy number variant sequencing (CNV-seq)/ chromosomal microarray analysis (CMA) and quantitative fluorescent polymerase chain reaction (QF-PCR) were selected, and the results from three the methods were compared and further analyzed. …”
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Fast Spot Locating for Low-Density DNA Microarray
Published 2025-03-01“…Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. …”
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Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes
Published 2001-02-01“…Our method provides a cost-effective alternative to conventional attachment strategies that is particularly suitable for genotyping PCR products with nucleic acid microarrays.…”
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Consistency and Stability in Feature Selection for High-Dimensional Microarray Survival Data in Diffuse Large B-Cell Lymphoma Cancer
Published 2025-02-01“…High-dimensional survival data, such as microarray datasets, present significant challenges in variable selection and model performance due to their complexity and dimensionality. …”
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Portable Fluorescence Microarray Reader-Enabled Biomarker Panel Detection System for Point-of-Care Diagnosis of Lupus Nephritis
Published 2025-01-01“…This study introduces an LED-based fluorescence reader designed for POC applications, enabling multiplex detection of lupus nephritis (LN) biomarkers using a biomarker microarray (BMA) slide. …”
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Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium
Published 2025-01-01“…All strains demonstrated effective straw biomass degradation compared to the negative control, with significant differences detected only in oil seed rape straw biodegradation estimations. …”
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Optimization based tumor classification from microarray gene expression data.
Published 2011-02-01“…<h4>Background</h4>An important use of data obtained from microarray measurements is the classification of tumor types with respect to genes that are either up or down regulated in specific cancer types. …”
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Comprehensive Review of Hybrid Feature Selection Methods for Microarray-Based Cancer Detection
Published 2025-01-01Subjects: Get full text
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Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A
Published 2025-08-01“…Herein, we present a newly developed nanostructured microarray based on silver-coated porous silicon (Ag-pSi) used as a surface-enhanced Raman scattering (SERS) transducer. …”
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Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing
Published 2025-06-01“…We further assessed and optimised reference-free aneuploidy detection using low-pass WGBS and assessed concordance with microarray-derived calls. …”
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Copula-Based Bayesian Model for Detecting Differential Gene Expression
Published 2025-04-01“…Finally, we apply our model to <i>Escherichia coli</i> microarray data, illustrating its practical utility in gene expression analysis.…”
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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
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A Network Analysis Approach to Detect and Differentiate Usher Syndrome Types Using miRNA Expression Profiles: A Pilot Study
Published 2024-11-01Subjects: Get full text
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Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing
Published 2025-07-01“…Conclusions Our findings strengthen that CMA is a rapid and effective genetic etiology diagnosis tool for miscarriages, producing the highest chromosomal abnormality detection rate at a gestational age of 10–11+6 weeks. …”
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Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…Conclusions: This hybridization array presents an accurate and cost-effective method for evaluating the disease-causing potential of Salmonella in outbreak investigations by targeting a selective set of Salmonella-associated virulence genes. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…Transfection efficiency was confirmed via qRT-PCR in HCT116 and SW480 colon cells, and the effects of circDOCK1 on cell proliferation, migration, and invasion were assessed.ResultsMicroarray data revealed 149 significantly differentially expressed circRNAs, including 71 upregulated and 78 downregulated circRNAs, in CRC tissues. …”
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Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…The classification achieved an average accuracy of 96%, demonstrating the effectiveness of the proposed approach. Feature selection using the Kruskal–Wallis and χ2 tests revealed statistically relevant genes contributing to subgroup discrimination. …”
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Ensemble Algorithm Based on Gene Selection, Data Augmentation, and Boosting Approaches for Ovarian Cancer Classification
Published 2024-12-01Subjects: Get full text
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Microarray Core Detection by Geometric Restoration
Published 2012-01-01“…Furthermore, the algorithm is more efficient than existing methods based on the Hough transform for circle detection. The algorithm’s simplicity, accuracy, and computational efficiency allow for automated high-throughput analysis of microarray images.…”
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Mutable Composite Firefly Algorithm for Microarray-Based Cancer Classification
Published 2025-01-01Subjects: “…Biomarker detection…”
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