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Effective detection of 148 cases chromosomal mosaicism by karyotyping, chromosomal microarray analysis and QF-PCR in 32,967 prenatal diagnoses
Published 2025-04-01“…Abstract Background Detection of mosaicism has always been difficult in prenatal diagnosis, which is to assess the value of karyotyping combined with three different molecular genetic tests for prenatal diagnosis. …”
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Fast Spot Locating for Low-Density DNA Microarray
Published 2025-03-01“…Low-density DNA microarrays are crucial in molecular diagnostics due to their cost-effectiveness and high sensitivity. …”
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Fabrication of DNA Microarrays Using Unmodified Oligonucleotide Probes
Published 2001-02-01“…Our method provides a cost-effective alternative to conventional attachment strategies that is particularly suitable for genotyping PCR products with nucleic acid microarrays.…”
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Portable Fluorescence Microarray Reader-Enabled Biomarker Panel Detection System for Point-of-Care Diagnosis of Lupus Nephritis
Published 2025-01-01“…This study introduces an LED-based fluorescence reader designed for POC applications, enabling multiplex detection of lupus nephritis (LN) biomarkers using a biomarker microarray (BMA) slide. …”
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Robust molecular subgrouping and reference-free aneuploidy detection in medulloblastoma using low-depth whole genome bisulfite sequencing
Published 2025-06-01“…We further assessed and optimised reference-free aneuploidy detection using low-pass WGBS and assessed concordance with microarray-derived calls. …”
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Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A
Published 2025-08-01“…Herein, we present a newly developed nanostructured microarray based on silver-coated porous silicon (Ag-pSi) used as a surface-enhanced Raman scattering (SERS) transducer. …”
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Copula-Based Bayesian Model for Detecting Differential Gene Expression
Published 2025-04-01“…Finally, we apply our model to <i>Escherichia coli</i> microarray data, illustrating its practical utility in gene expression analysis.…”
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Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing
Published 2025-07-01“…Conclusions Our findings strengthen that CMA is a rapid and effective genetic etiology diagnosis tool for miscarriages, producing the highest chromosomal abnormality detection rate at a gestational age of 10–11+6 weeks. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…Transfection efficiency was confirmed via qRT-PCR in HCT116 and SW480 colon cells, and the effects of circDOCK1 on cell proliferation, migration, and invasion were assessed.ResultsMicroarray data revealed 149 significantly differentially expressed circRNAs, including 71 upregulated and 78 downregulated circRNAs, in CRC tissues. …”
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Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…The objective of this study is to demonstrate the use of a robust and inexpensive microarray platform to assay the virulence gene profiles in Salmonella from food and/or the food animal environment, and then use ArrayTrackTM for data analysis. …”
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Microarray Core Detection by Geometric Restoration
Published 2012-01-01“…Furthermore, the algorithm is more efficient than existing methods based on the Hough transform for circle detection. The algorithm’s simplicity, accuracy, and computational efficiency allow for automated high-throughput analysis of microarray images.…”
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A Sensitive and Fast microRNA Detection Platform Based on CRlSPR-Cas12a Coupled with Hybridization Chain Reaction and Photonic Crystal Microarray
Published 2025-04-01“…The target sequence was amplified simply and isothermally, enabling the test to be executed at a constant temperature of 37 °C. The detection platform had the capacity to measure concentrations down to the picomolar level, and the target miRNA could be distinguished at the nanomolar level. …”
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Systematic spatial bias in DNA microarray hybridization is caused by probe spot position-dependent variability in lateral diffusion.
Published 2011-01-01“…Numerical simulations reveal a strong influence of microarray well geometry on the spatial bias.<h4>Conclusions</h4>Reciprocal adjustment of the size of the microarray hybridization chamber to the area of surface-bound probes is a simple and effective measure to minimize or eliminate the diffusion-based bias, resulting in increased uniformity and accuracy of quantitative DNA microarray hybridization.…”
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Photopolymerization as an innovative detection technique for low-density microarrays
Published 2008-08-01“…One limitation that accounts in part for the scarcity of commercially available diagnostic microarrays is the expense associated with fluorescence detection. …”
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Oral Bacteria of Children with Turner Syndrome
Published 2019-03-01“…Plaque index and gingival index levels were significantly higher in the Turner group and dft was significantly higher in the control group (p<0.05). As a result, microarray analysis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus were detected at high levels in the Turner group (p<0.05).Conclusion:Besides dental and craniofacial anomalies, clinicians should be alert to the early diagnosis and treatment of periodontal problems in patients with TS.…”
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A Network Analysis Approach to Detect and Differentiate Usher Syndrome Types Using miRNA Expression Profiles: A Pilot Study
Published 2024-11-01“…<b>Methods:</b> We collected microarray miRNA-expression data from 17 samples, representing four patient-derived USH cell lines and a non-USH control. …”
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Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium
Published 2025-01-01“…All strains demonstrated effective straw biomass degradation compared to the negative control, with significant differences detected only in oil seed rape straw biodegradation estimations. …”
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A standardized fold change method for microarray differential expression analysis used to reveal genes involved in acute rejection in murine allograft models
Published 2018-03-01“…We suggest that SFC can be utilized to stably and effectively detect differential gene expression and to explore microarray data in further studies.…”
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Deep Residual Transfer Ensemble Model for mRNA Gene-Expression-Based Breast Cancer
Published 2025-01-01Subjects: “…Breast cancer detection…”
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