Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy by Xiaohong Liu, Yue Sun, Boxu Lin, Hao Xiong, Xinyue Lu, Binghe Tan, Chenglin Zhang, Mingyao Liu, Juliang Qin, Na Zhang, Bing Du

“…Abstract Background Chimeric antigen receptor T (CAR-T) cell therapy has shown remarkable success in treating hematologic malignancies. However, its efficacy against solid tumors remains limited. …”
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In vitro biological activities of silver nanoparticles using methanolic leaf extract of Plumeria rubra by Abhinash Marukurti, Alavala Matta Reddy, Pangi Vijaya Nirmala, Dasari Kalyani, K. Ramaneswari, I. J. N. Padmavathi, L. Pradeepthi Pemmaraju, Gotham Samuel Silvanus, Buddha Sai Keerthana, Shaik Farhana, D. Ramachandran, B. Mallikarjuna, Phanindra Babu Kasi

“…The phytochemistry of PR extract was observed using qualitative screening, Fourier transform infrared spectroscopy (FTIR), and gas chromatography with flame ionisation detection (GC-FID). The observed surface plasmon resonance using UV-visible spectroscopy confirmed the formation of PR-AgNPs, and the surface functionalization identified with FTIR correlated with the phytochemistry of the PR extract. …”
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Health-Related Messages About Herbs, Spices, and Other Botanicals Appearing in Print Issues and Websites of Legacy Media: Content Analysis and Evaluation by Ann Gaba, Richard Bennett

“…Therefore, legacy media may be considered a credible source of information to readers about these topics.…”
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Whole-genome sequencing and genomic analysis of four Akkermansia strains newly isolated from human feces by Wenjing Lu, Biqing Zha, Jie Lyu, Chenxi LingHu, Jing Chen, Sisi Deng, Xiangling Zhang, Liang Li, Guoqing Wang

“…Moreover, 2,184 shared homologous genes were identified among the four isolates. Functional annotation using the COG, KEGG, and CAZy databases indicated that the functional genes of the four isolates were primarily associated with metabolism. …”
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Acetone gas sensor based on chitosan-metal-organic framework mixed matrix membranes for diabetes diagnosis by Lamia A. Siddig, Ashraf Ali, Shaikha S. Al Neyadi, Yaser E. Greish, Stefan Wuttke, Saleh T. Mahmoud

“…Detecting diabetes in its early stages through non-invasive methods remains a major challenge for researchers. …”
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Differential expression of five genes during sclerotium formation of Rhizoctonia solani by WANG Wei, YANG Hui, WANG Zhengyi, CHEN Weiliang

“…Rhizoctonia solani is an important plant pathogenic fungus with a wide host range and worldwide distribution, and the sclerotia are the main source of infection for the diseases caused by this pathogen. …”
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Exploring the Possibility of Medical Device Surveillance in Patients on Peritoneal Dialysis Using a Common Data Model by Seon Min Kim, Sooin Choi, You Kyoung Lee, Cheol Wan Lim, Byung Chul Yu, Moo Yong Park, Jin Kuk Kim, Seng Chan You, Seo Jeong Shin, Soo Jeong Choi

“…After implementing amended matching, these data were detected. <i>Conclusions</i>: While some PD-related medical data recorded in EHRs were misrepresented or omitted during the CDM database extraction, transformation, and loading process, the CDM shows potential to serve as a source of real-world data for active surveillance.…”
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HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer by Qing Wang, Maha Ayyoub, Olivia Le Saux, Paola Bonaventura, Isabelle Treilleux, Nicolas Chopin, Clarisse Dubois, Virginie Mutez, Nicolas Chuvin, Yann Estornes, Jenny Valladeau-Guilemond, Stephane Depil, Nicolas Gadot, Marie Michelas, Audrey Page, Olivier Tabone, Marie Delles, Sarah Moran, Thibault Richard, Marjorie Lacourrège, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez

“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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From warehouse to ward: applying implementation research methods to the device identification, qualification, distribution, and management process within the Newborn Essential Solu... by Kylie Dougherty, Rebecca P. Kirby, Katerina Claud, Kara M. Palamountain, Elizabeth Asma, Millicent Alooh, Danica Kumara, Vince Gate, Ali Khalid, George Banda, Hope David Peter, Charles Osuagwu, Rebecca Richards-Kortum, Z. Maria Oden, Christine A. Bohne, Lisa R. Hirschhorn

“…We applied implementation research (IR) to understand context, describe strategy selection, and implementation outcomes of the work designed to ensure the consistent availability of functional SSNC devices. …”
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Enabling beam-scanning antenna technologies for terahertz wireless systems: A review by Dongze Zheng, Geng-Bo Wu, Zhi Hao Jiang, Wei Hong, Chi Hou Chan, Ke Wu

“…While producing a scannable highly-directive antenna beam proves to be indispensable in the period of microwaves, the significance of such functionality is more critical in the THz era, considering that THz waves have more intractable challenges such as the severity of free-space propagation losses, the susceptibility to atmospheric environments, and the unavailability of efficient signal sources. …”
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Recent Advances in Understanding the Keys Factors Influencing Pressurized Liquid Extraction of Secondary Metabolites: A Comprehensive Review by Pauline Donn, Sepidar Seyyedi-Mansour, Franklin Chamorro, Paula Garcia-Oliveira, Javier Echave, Ana Perez-Vazquez, Paula Barciela, Lucia Cassani, Miguel Angel Prieto

“…., phenolic compounds) from botanical sources, with implications spanning across pharmaceuticals, nutraceuticals, and functional foods. …”
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Further Evidence on the Role of Thyroid Autoimmunity in Women with Recurrent Miscarriage by Natalia Lazzarin, Costanzo Moretti, Giovanna De Felice, Elena Vaquero, Dario Manfellotto

“…Our data support the hypothesis that in patients with RM the presence of TAI is an indirect sign of a subtle thyroid dysfunction detectable by a specific test. This test give the possibility to identify women with RM in which specific therapeutic approaches could effectively improve the possibility for a successful pregnancy.…”
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Construction of a myocardial and skeletal muscle-specific Cyr61 gene knockout mouse model by XU Diyan, ZHANG Wenli, ZUO Yidan, SU Zhen

“…The skeletal muscle function of Cyr61 knockout mice was evaluated and following related indicators in the myocardium and skeletal muscle were detected by Western blot: Aging (p53, p21),inflammatory response (TNF-α,IL-18,IL-1β),fibrosis (vimentin,TGF-β,α-SMA,COL1). …”
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Gut dysbiosis narrative in psoriasis: matched-pair approach identifies only subtle shifts correlated with elevated fecal calprotectin by Bayazit Yunusbayev, Anna Bogdanova, Nadezhda Nadyrchenko, Lavrentii Danilov, Viktor Bogdanov, Grigory Sergeev, Radick Altinbaev, Fanil Bilalov, Milyausha Yunusbaeva

“…We next showed that these enriched species were correlated with elevated biomarkers of intestinal and systemic inflammation and liver function. Functionally, one of the top species, Megasphaera elsdenii, is a potent lactate utilizer in the context of intestinal lactic acidosis and inflammation. …”
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MicroRNAs obtained from cervical swabs in predicting preterm birth by Rosalia Purbandari, Suheni Ninik Hariyati

“…Under stress conditions, their regulatory functions become significant, linking them to disease states. …”
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Mobile health apps for skin cancer triage in the general population: a qualitative study on healthcare providers’ perspectives by Tobias E. Sangers, Marlies Wakkee, Folkert Moolenburgh, Tamar Nijsten, Marjolein Lugtenberg

“…Conclusions Although HCPs perceive pivotal risks related to the implementation of mHealth apps, they also foresee important benefits when implemented successfully. In order for HCPs to endorse those apps, emphasis must be placed on integrating accurate mHealth apps with accessible and inclusive design and functionality into clinical practice, factors that currently appear to be largely unmet.…”
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Challenges and Management Strategies for Mediterranean Cork Oak Forests: Impacts of Climate Change, Human Activities, and Invasive Species – A Review by Mesfin Boja, Kaouther Mechergui, Wahbi Jaouadi, Youssef Ammari

“…Long-term monitoring and proactive management strategies are crucial for early detection and control of invasive species and diseases, which will help mitigate their impacts and support forest health. …”
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Target Selection, Homokaryotic Isolation, and Screening Methods for Gene Editing in the Destructive Global Pathogen, <i>Phytophthora cinnamomi</i> by Aayushree Kharel, Mark Ziemann, Jim Rookes, David M. Cahill

“…While gene editing has emerged as a powerful tool for functional genomics in various <i>Phytophthora</i> species, its application in <i>P. cinnamomi</i> remains underexplored. …”
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Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasia<subtitle>An animal experimental study</subtitle> by Qi Xu, Xiao-hui Xu, Ze-zheng Liu, Jian-bi Zhu, Huan-huan Ding, Chun-chun Jin, Zhi-han Yan

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Wisdom of the Established Pattern by Joel Janhonen

“…According to Jonathan Haidt, even our moral reasoning mainly functions as a post-hoc confirmation of the preceding affective judgments.[1] The constructed rationalizations are our attempt to understand and unravel the mystery of our intuition and its pragmatic insights. …”
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