Effectiveness of exercise therapy in patients with knee osteoarthritis: an overview of systematic reviews by Daisuke Sasaki, Takashi Kitagawa, Yuichi Isaji, Kunihiro Onishi, Masateru Hayashi, Wataru Okuyama

“…Objective This study aimed to assess the methodological quality of published systematic reviews of exercise therapy in knee osteoarthritis and summarise their reported effectiveness on quality of life, knee joint function, or adverse events.Design Overview of systematic reviews.Data sources PubMed, Embase, CINAHL, Web of Science and CENTRAL (searched on 14 April 2025), plus grey literature (PROSPERO, Epistemonikos, OpenGrey).Eligibility criteria for selecting studies We included systematic reviews of randomised controlled trials in patients diagnosed with knee osteoarthritis by imaging or clinical criteria and treated conservatively with exercise therapy; we excluded reviews that enrolled patients scheduled for surgery, with acute inflammation or osteoarthritis of other joints (hand, hip, ankle), for which relevant author data could not be obtained after one contact attempt, or that did not report at least one primary outcome (quality of life, knee joint function or adverse events).Data extraction and synthesis Two reviewers independently extracted data on study characteristics, interventions and outcomes, and assessed methodological quality using the AMSTAR 2 (A MeaSurement Tool to Assess systematic Reviews 2) tool. …”
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Effect of Dry, Vacuum, and Modified Atmosphere Ageing on Physicochemical Properties of Roe Deer Meat by Natalia Kasałka-Czarna, Róża Biegańska-Marecik, Jędrzej Proch, Aleksandra Orłowska, Magdalena Montowska

“…Roe deer meat, due to the natural origin, is a source of organic and healthy meat. The selection of suitable storage conditions and times plays an important role in a deterioration of the meat's functional and nutritional values. …”
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Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…In conclusion, our results provide the immune landscape of necrotizing granulomas and reveal novel functional states of macrophages contributing to TB pathogenesis.…”
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New Thermoelectric Sensor Adapted to Realize an Infrared Radiations Detector by Mohammed Rahmoun, Khalid Hachami, Abdelwahad Touil, Benaissa Bellach, Mohammed Bailich, Ammar Merdani

“…The present paper deals with the design and the realization of a new thermoelectric sensor (Seebeck), sensitive to the infrared radiations emitted by different sources. The function mechanism utilizes radiative absorption phenomena, heat transfer, and thermoelectric effects. …”
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<i>In silico</i> prediction of the transcription factor-enhancer interaction as a first stage of axonal growth regulation by D. D. Kotelnikov, I. A. Sinyakin, E. A. Borodin, T. A. Batalova

“…The enhancer sequence of DCC and SHH protein genes were taken from the NCBI open-source database in FASTA format. Ensembl database was used for enhancer mapping, GeneCards was used for screening and selection of potentially appropriate enhancers and transcription factors associated with these enhancers. …”
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Activity tracking devices in pregnancy: Understanding the participant experience in a longitudinal birth cohort by Ashley Redding, Dionne Coates, Andrea E. Cassidy-Bushrow, Jennifer K. Straughen, Sara Santarossa

“…REACH-Fitbit participants had to be <20 weeks gestation with access to a Bluetooth-enabled device. Recruitment (self-selection) for focus groups occurred from completed REACH-Fitbit participants (e.g., delivered their baby). …”
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Bioinformatics analysis to explore biomarkers and mechanisms of action associated with endoplasmic reticulum stress and ferroptosis in Parkinson's disease. by Hao Wang, Lijuan Feng, Limeng He, Nan Liu, Yan Wan, Wei Zhang

“…<h4>Methods</h4>Data for PD and ERS, as well as information on ferroptosis, were sourced from public databases and relevant literature. …”
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Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05 by Randa Harrat, Ghania Bourzama, Gaëtan Burgaud, Emmanuel Coton, Aymen Bourezgui, Boudjema Soumati

“…SEM analysis revealed morphological alterations, including cracks and holes, ATR-FTIR detected new functional groups (alcohols, alkynes, aldehydes, alkenes and ketones), while XRD identified changes in the polymer crystallinity and phase composition. …”
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Nurses’ usage of validated tools to assess for delirium in general acute care settings: A scoping review protocol [version 1; peer review: 2 approved] by Aoibhinn Boyd, Leona Bannon, Marcia Kirwan

“…It often affects hospital in-patients and is associated with an increased risk of mortality, dementia, and functional decline. Delirium can be detected through the use of validated assessment tools, administered by nurses, and early detection is associated with improved outcomes for patients. …”
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Comparative metabolomic profiling of Lupinus albus and L. angustifolius harvest residues: exploring chemical diversity and valorization potential by Salma Halime, Salma Halime, Jenny Renaut, Stéphanie Zimmer, Hanna Heidt, Cédric Jacquard, Kjell Sergeant

“…Lupin species are a rich source of bioactive compounds with diverse industrial applications, yet their harvest residues remain underutilized. …”
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An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment by Enzo Romero, Jose G. Garcia, Magno Parra, Sebastian Caballa, Alejandro M. Saldarriaga, Edson F. Luque, Dante J. Rodriguez, Victoria E. Abarca, Dante A. Elias

“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
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Rainbow Vectors for Broad-Range Bacterial Fluorescence Labeling. by Mariette Barbier, F Heath Damron

“…Only E2-Crimson, mCherry and mKeima were successfully detected for in vivo applications. Overall, E2-Crimson was the fastest maturing protein tested in E. coli with the best overall performance in the study parameters. …”
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Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro. by Daniel Koch, Ay Lin Kho, Atsushi Fukuzawa, Alexander Alexandrovich, Kutti J Vanaanen, Andrew Beavil, Mark Pfuhl, Martin Rees, Mathias Gautel

“…To study substrate specificity, mechanism and regulation of obscurin GEF function by individual domains, we successfully optimized recombinant production of obscurin GEF domains and found that MST-family kinases phosphorylate the obscurin DH domain at Thr5798. …”
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A systematic review of mapping strategies for the sonification of physical quantities. by Gaël Dubus, Roberto Bresin

“…Results confirm two hypotheses formulated in a preliminary study: pitch is by far the most used auditory dimension in sonification applications, and spatial auditory dimensions are almost exclusively used to sonify kinematic quantities. To detect successful as well as unsuccessful sonification strategies, assessment of mapping efficiency conducted in the reviewed works was considered. …”
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The changes of microbial diversity and flavor compounds during the fermentation of millet Huangjiu, a traditional Chinese beverage. by Yi Yan, Haiyan Chen, Leping Sun, Wei Zhang, Xin Lu, Zhenpeng Li, Jialiang Xu, Qing Ren

“…Flavor compounds reflect the quality and health function of Huangjiu. The flavor compounds of Huangjiu are complex and their formation is closely associated with microorganisms, but the relationship between them during fermentation has been unknown. …”
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Digital Platforms for the Built Environment: A Systematic Review Across Sectors and Scales by Michele Berlato, Leonardo Binni, Dilan Durmus, Chiara Gatto, Letizia Giusti, Alessia Massari, Beatrice Maria Toldo, Stefano Cascone, Claudio Mirarchi

“…Unlike existing reviews focused on single technologies or sectors, this work offers a cross-sectoral synthesis, highlighting shared challenges and opportunities across disciplines and lifecycle stages. It identifies the functional roles, enabling technologies and systemic barriers affecting digital platform adoption, such as fragmented data sources, limited interoperability between systems and siloed organizational processes. …”
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Cortical layer-specific abnormalities in auditory responses in a mouse model of Fragile X Syndrome by Katrina E. Deane, Devin K. Binder, Khaleel A. Razak

“…Sensory sensitivity and temporal processing deficits in the auditory domain will affect development of language and cognitive functions. The mouse model for FXS, Fmr1 KO, has shown remarkably similar auditory processing phenotypes to patients with FXS. …”
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Mineral composition in mussel Mytilus galloprovincialis and clam Tapes decussatus from Faro Lake of Messina: risk assessment for human health by Fabio Bruno, Vincenzo Nava, Sebastiano Zappalà, Giovanna Lucrezia Costa, Francesco Fazio, Vincenzo Parrino, Patrizia Licata

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Research note: Harnessing the potential of chicken blastodermal cells as a new frontier in poultry science and biotechnology – Establishment of embryonic stem cells and their diffe... by Małgorzata Duda, Patrycja Maciak, Grzegorz Tylko, Kamil Wartalski, Monika Trzcińska, Marek Romek, Marcin Samiec

“…The current study demonstrates, for the first time, the successful differentiation of chicken B-ESCs into SC-LCs through ex-ovo sequential culture. …”
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Identification and Comprehensive Evaluation of Drought Tolerance in Sorghum During Germination and Seedling Stages by Manhong Wang, Irshad Ahmad, Bin Qin, Lei Chen, Weicheng Bu, Guanglong Zhu, Guisheng Zhou

“…In this study, 19 sorghum varieties from both domestic and international sources were selected as experimental materials. At the seedling stage, 11 above-ground and below-ground phenotypic traits were investigated. …”
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