Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

“…Emerging strategies, such as selective NOX inhibitors, antioxidant therapies, and agents modulating signaling transduction, offer promising avenues for mitigating oxidative injury and improving cardiac function. …”
Get full text

VERY LOW CALORIE DIETS AFFECT LONG TERM WEIGHT LOSS AND HEALTH OUTCOMES: A SYSTEMATIC REVIEW by Sheila Amara Putri, Shintia Yunita Arini, Dominikus Raditya Atmaka, S.Gz, MPH, Ardyanisa Raihan Kusuma, Anisah Firdaus Rahmawati, Mutiara Arsya Wijanarko, Norfezah Md Nor, Nadiatul Syima Mohd Shahid

“…Result: Ten from 1063 studies qualified the selection criteria. VLCD success in weight loss depends on treatment type, duration, physical activity, and genetics. …”
Get full text

Determination of Pipe Diameter Using Optimization Method by Pavlov Mikhail Vasilyevich, Vafaeva Khristina Maksudovna, Karpov Denis Fedorovich, Bhatnagar Sanjay, Kommanaboina Uma Shankar, Sharma Dikshit, Singh Digvijay, Sateesh N., Singh Pankaj Kumar

“…During the design phase of engineering networks, a critical issue remains the selection of pipe diameters that minimize capital investments for transporting the heat carrier from the heat source to the consumers. …”
Get full text

Linguistic Features of the Ergonomic Space of the Central Streets of Yoshkar-Ola and Kazan by Iraida G. Ivanova, Flera Ya. Khabibullina

“…Urbanonyms as names of objects of various functional profiles are an indicator of preferred languages for naming urban objects, and act as a marker of the spheres of functioning of languages in a given territory. …”
Get full text

Presenting the Physical Pattern of Today's Housing by Taking Advantage of the Desirable Qualities of Historical Houses (Case Study: Kerman City) by Amjad Bahredar, Ramin Madani, Mohsen Afshari

“…These qualities, in addition to meeting their functional needs, seek to solve the superior needs of the residents. …”
Get full text

Effectiveness of exercise therapy in patients with knee osteoarthritis: an overview of systematic reviews by Daisuke Sasaki, Takashi Kitagawa, Yuichi Isaji, Kunihiro Onishi, Masateru Hayashi, Wataru Okuyama

“…Objective This study aimed to assess the methodological quality of published systematic reviews of exercise therapy in knee osteoarthritis and summarise their reported effectiveness on quality of life, knee joint function, or adverse events.Design Overview of systematic reviews.Data sources PubMed, Embase, CINAHL, Web of Science and CENTRAL (searched on 14 April 2025), plus grey literature (PROSPERO, Epistemonikos, OpenGrey).Eligibility criteria for selecting studies We included systematic reviews of randomised controlled trials in patients diagnosed with knee osteoarthritis by imaging or clinical criteria and treated conservatively with exercise therapy; we excluded reviews that enrolled patients scheduled for surgery, with acute inflammation or osteoarthritis of other joints (hand, hip, ankle), for which relevant author data could not be obtained after one contact attempt, or that did not report at least one primary outcome (quality of life, knee joint function or adverse events).Data extraction and synthesis Two reviewers independently extracted data on study characteristics, interventions and outcomes, and assessed methodological quality using the AMSTAR 2 (A MeaSurement Tool to Assess systematic Reviews 2) tool. …”
Get full text

Effect of Dry, Vacuum, and Modified Atmosphere Ageing on Physicochemical Properties of Roe Deer Meat by Natalia Kasałka-Czarna, Róża Biegańska-Marecik, Jędrzej Proch, Aleksandra Orłowska, Magdalena Montowska

“…Roe deer meat, due to the natural origin, is a source of organic and healthy meat. The selection of suitable storage conditions and times plays an important role in a deterioration of the meat's functional and nutritional values. …”
Get full text

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles by Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger

“…Abstract Extracellular vesicles (EVs) have emerged as sources of promising, minimally invasive biomarkers for diagnosing and monitoring diseases like Alzheimer's. …”
Get full text

<i>In silico</i> prediction of the transcription factor-enhancer interaction as a first stage of axonal growth regulation by D. D. Kotelnikov, I. A. Sinyakin, E. A. Borodin, T. A. Batalova

“…The enhancer sequence of DCC and SHH protein genes were taken from the NCBI open-source database in FASTA format. Ensembl database was used for enhancer mapping, GeneCards was used for screening and selection of potentially appropriate enhancers and transcription factors associated with these enhancers. …”
Get full text

Activity tracking devices in pregnancy: Understanding the participant experience in a longitudinal birth cohort by Ashley Redding, Dionne Coates, Andrea E. Cassidy-Bushrow, Jennifer K. Straughen, Sara Santarossa

“…REACH-Fitbit participants had to be <20 weeks gestation with access to a Bluetooth-enabled device. Recruitment (self-selection) for focus groups occurred from completed REACH-Fitbit participants (e.g., delivered their baby). …”
Get full text

Bioinformatics analysis to explore biomarkers and mechanisms of action associated with endoplasmic reticulum stress and ferroptosis in Parkinson's disease. by Hao Wang, Lijuan Feng, Limeng He, Nan Liu, Yan Wan, Wei Zhang

“…<h4>Methods</h4>Data for PD and ERS, as well as information on ferroptosis, were sourced from public databases and relevant literature. …”
Get full text

Digital Platforms for the Built Environment: A Systematic Review Across Sectors and Scales by Michele Berlato, Leonardo Binni, Dilan Durmus, Chiara Gatto, Letizia Giusti, Alessia Massari, Beatrice Maria Toldo, Stefano Cascone, Claudio Mirarchi

“…Unlike existing reviews focused on single technologies or sectors, this work offers a cross-sectoral synthesis, highlighting shared challenges and opportunities across disciplines and lifecycle stages. It identifies the functional roles, enabling technologies and systemic barriers affecting digital platform adoption, such as fragmented data sources, limited interoperability between systems and siloed organizational processes. …”
Get full text

Identification and Comprehensive Evaluation of Drought Tolerance in Sorghum During Germination and Seedling Stages by Manhong Wang, Irshad Ahmad, Bin Qin, Lei Chen, Weicheng Bu, Guanglong Zhu, Guisheng Zhou

“…In this study, 19 sorghum varieties from both domestic and international sources were selected as experimental materials. At the seedling stage, 11 above-ground and below-ground phenotypic traits were investigated. …”
Get full text

Erythrina lysistemon Hutch. abates deranged metabolic indices linked with diabetic complications in experimental rat model by Kolawole Olofinsan, Veronica Salau, Ochuko Erukainure, Md. Shahidul Islam

“…This study investigated the in vivo activity of E. lysistemon bark extract on animal models of type 2 diabetes (T2D) and complications vis-a-vis the effects on pancreatic functional enzymes and morphology, serum biochemical profile, and hepatic glucose metabolism. …”
Get full text

Femtosecond laser subtractive/additive-integrated biomimetic manufacturing for visible/infrared encryption and stimuli-responsive infrared decryption by Ruijie Liu, Dongshi Zhang, Zhuguo Li

“…The blackening efficiency of this technique can reach ∼11.25 cm ^2 ·min ^−1 , opening opportunities for high-throughput optical/thermal applications. Selectively patterned Chinese characters, Arabic numbers, and English letters are easily fabricable, which are intrinsically invisible-infrared dual-band encrypted but decryptable via static/dynamic environment stimuli (e.g., sample heating/cooling, introducing external hot/cold sources including human hands). …”
Get full text

Prevalence of autoimmune thyroid disease in patients with psoriasis: a meta-analysis by Peng Zhang, Ruifang Wu, Xiaochao Zhang, Suhan Zhang, Siying Li, Yuwen Su

“…This meta-analysis aims to determine the association between psoriasis and AITD.Design A meta-analysis of observational studies.Data sources PubMed, EMBASE, Scopus and the Cochrane Library were searched up to 1 November 2021.Eligibility criteria for selecting studies We included non-randomised studies, each with over 50 cases in every group, focusing on the rate of comorbidity between psoriasis and AITD.Data extraction and synthesis Two independent reviewers screened the articles and extracted data. …”
Get full text

Advanced capabilities for in vitro stress diagnostics: a review by Yana G. Pekhova, Anna A. Kuzyukova, Larisa A. Marchenkova

“…Comprehensive assessment of modern possibilities of stress objectification using laboratory diagnostics of its markers based on data from literary sources. MATERIALS AND METHODS. To select publications, we studied the PubMed, Web of Science (Web of Science Core Collection and Medline), Cochrane Library databases, included data from meta-analyses and review articles, full-text articles investigating the relationship between laboratory biomarkers and stress. …”
Get full text

Chemometrically assisted optimization and validation of the HPLC method for the analysis of alectinib and its related impurity with measurement uncertainty evaluation and whiteness... by Serkan Levent, Abeer Elriş, Hazal Avcı, Saniye Özcan, Nafiz Öncü Can

“…The method’s optimization was carried out using the Box-Behnken design, whereas the optimized conditions were selected according to the desirability function. Validation of the method was done with the International Council for Harmonization, ICH Q2(R2) Guidelines. …”
Get full text

Household ownership of latrines does not ensure use: a scoping review by Nicolas Gaffan, Cyriaque Degbey, Alphonse Kpozehouen, Moussiliou Noël Paraïso, Yolaine Glele Ahanhanzo

“…Objective This study aimed to conduct a scoping review of the factors associated with latrine utilisation by households.Design We performed a scoping review to determine the factors associated with household latrine utilisation.Data sources We conducted a bibliographic search using PubMed, Google Scholar, ScienceDirect, Epistemonikos and Semantic Scholar until April 2023.Eligibility criteria The papers we included met the following criteria: the study population included members of households equipped with latrines, regardless of their status, excluding children under five; the study followed an observational design; the study design was quantitative; the manuscript was in either French or English; the study focused on factors associated with latrine utilisation; the study employed multivariate methods and the study manuscript was published in a peer-reviewed journal.Data extraction and synthesis We conducted a narrative synthesis of key results.Results This review selected 31 articles. …”
Get full text

Energy Efficiency of Using Hybrid Heating Points in Conditions of Integration of Electrical and Thermal Networks of Urban Neighborhoods. Part 1. Justification of the Feasibility of... by A. V. Sednin, M. I. Pozdnyakova

“…If during the new construction the power of the electrical network may vary depending on the selected option, then during the modernization of the heat supply system, the problem is solved if there is a limitation on the available electrical power. …”
Get full text