GASTROINTESTINAL BLEEDING WITH THE USE OF NEW ORAL ANTICOAGULANTS: EPIDEMIOLOGY, RISK FACTORS, TREATMENT, AND PREVENTION by E. V. Moroz, A. E. Karateev, E. V. Kryukov, V. A. Chernetsov

“…Novel oral anticoagulants (NOACs), such as the direct thrombin inhibitor dabigatran and the selective factor Xa inhibitors rivaroxaban and apixaban, are increasingly used as an effective antithrombotic drug in real clinical practice. …”
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REGULATORY INTEGRATION IN THE HEALTHCARE SECTOR OF UKRAINE by Mykhailo D. Diachuk

“…Materials and methods. 20 regulatory and legal documents and 16 scientific literary sources on the topic of the research materials were selected. …”
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Green Chemistry Method for Analyzing Bisphenol A in Milk by Angela M. Encerrado Manriquez, Wen-Yee Lee

“…A simple, fast, green, and sensitive method for determining Bisphenol A (BPA) levels in commercial milk was developed using a solventless sample preparation technique known as stir bar sorptive extraction, coupled with thermal desorption–gas chromatography/mass spectrometry. BPA was selected due to its ubiquitous presence in the environment and its classification as an endocrine-disrupting chemical of concern (i.e., its ability to mimic hormone functions). …”
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Live and heat-killed Leuconostoc mesenteroides counteract the gastrointestinal dysfunction in chronic kidney disease mice through intestinal environment modulation. by Fittree Hayeeawaema, Natthawan Sermwittayawong, Chittipong Tipbunjong, Nawiya Huipao, Paradorn Muangnil, Pissared Khuituan

“…This study aimed to evaluate the probiotic potential of lactic acid bacteria derived from natural sources and to investigate the effects of both live and heat-killed Leuconostoc mesenteroides (Ln.m) on renal and gastrointestinal functions in CKD mice. …”
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Sequential Inversion for Helicopter Time-Domain Electromagnetics Based on a Regularized Extended Kalman Filtering by Sirui Zhou, Jun Lin, Chuandong Jiang, Haigen Zhou, Yanzhang Wang

“…The helicopter time-domain electromagnetic method (HTEM) has been widely applied in challenging geological terrains, particularly in large-scale mineral exploration, underground water resource detection, and the selection of sites for underground engineering, due to its advantage of not requiring personnel to enter the detection area. …”
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Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes by Georgy Smyshlyaev, Alex Bateman, Orsolya Barabas

“…Tyrosine recombinase (YR) proteins drive MGE mobilization and could provide markers for MGE detection, but they constitute a diverse family also involved in housekeeping functions. …”
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Targeting Amyloid Pathology in Early Alzheimer’s: The Promise of Donanemab-Azbt by Nadia Khartabil, Ayda Awaness

“…It specifically targets and reduces amyloid beta plaques, a hallmark of the disease, potentially slowing progression and preserving cognitive function. However, its administration requires careful patient selection, including genetic testing for ApoE ε4 status, to mitigate risks of ARIA. …”
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Rehabilitation impact indices and their independent predictors: a systematic review by Amardeep Thind, Gerald Choon-Huat Koh, Robert Petrella, Cynthia Huijun Chen

“…Objectives To (1) identify all available rehabilitation impact indices (RIIs) based on their mathematical formula, (2) assess the evidence for independent predictors of each RII and (3) propose a nomenclature system to harmonise the names of RIIs.Design Systematic review.Data sources PubMed and references in primary articles.Study selection First, we identified all available RII through preliminary literature review. …”
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3D-MRI brain glioma intelligent segmentation based on improved 3D U-net network. by Tingting Wang, Tong Wu, Defu Yang, Ying Xu, Dongyang Lv, Tong Jiang, Hengjiao Wang, Qi Chen, Shengnan Xu, Ying Yan, Baoguang Lin

“…This method offers significant guidance for medical diagnosis, grading, and treatment strategy selection.<h4>Methods</h4>Glioma case data were sourced from the BraTS2023 public dataset. …”
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A probabilistic approach for building disease phenotypes across electronic health records by David Vidmar, Jessica De Freitas, Will Thompson, John M. Pfeifer, Brandon K. Fornwalt, Noah Zimmerman, Riccardo Miotto, Ruijun Chen

“…In this paper, we develop multiple heuristic “labeling functions’’ (LFs) for 4 diseases across de-identified EHR data and aggregate their votes through a majority vote approach (MV), a popular open-source approach (Snorkel OSS), and our proposed probabilistic approach (LEVI). …”
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Classification analysis of modern bioreactor systems (review). Part 1. Classification of bioreactors by design parameters by A. A. Dosaev, R. R. Safarov, N. V. Menshutina

“…Due to the active use of bioreactors, in order to optimize production processes and reduce operating costs, new highly efficient automated devices with a variety of functions are being developed using modern automation technologies, artificial intelligence and 3-D printing. …”
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Deepmol: an automated machine and deep learning framework for computational chemistry by João Correia, João Capela, Miguel Rocha

“…On 22 benchmark datasets, DeepMol obtained competitive pipelines compared with those requiring time-consuming feature engineering, model design and selection processes. As one of the first AutoML tools specifically developed for the computational chemistry domain, DeepMol stands out with its open-source code, in-depth tutorials, detailed documentation, and examples of real-world applications, all available at https://github.com/BioSystemsUM/DeepMol and https://deepmol.readthedocs.io/en/latest/ . …”
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Comparative Genomic and Transcriptomic Analysis Provides New Insights into the Aflatoxin B₁ Biodegradability by <i>Kocuria rosea</i> from Deep Sea by Jingying Wang, Jun Nan

“…In addition, this study revealed 1421 differentially expressed genes and 752 upregulated genes between the aflatoxin group and the control group through transcriptome analysis and conducted functional annotation and analysis of functional enrichment. …”
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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

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Regenerative Cartilage Treatment for Focal Chondral Defects in the Knee: Focus on Marrow-Stimulating and Cell-Based Scaffold Approaches by Filippo Migliorini, Francesco Simeone, Tommaso Bardazzi, Michael Kurt Memminger, Gennaro Pipino, Raju Vaishya, Nicola Maffulli

“…Given the limited regenerative capacity of hyaline cartilage, biologically based surgical strategies have emerged to promote tissue repair and restore joint function. This narrative review critically examines current treatment approaches that rely on autologous cell sources and scaffold-supported regeneration. …”
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Harnessing polydiacetylene (PDA): A review of structural mechanics and infectious disease detection by Soumendu Patra, Harshita Shand, Sayan Ghosal, Suvankar Ghorai

“…These biosensors can also be functionalized with particular capture agents, such as antibodies or nucleic acid probes, to selectively bind and detect the target analytes. …”
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The therapeutic validity and effectiveness of physiotherapeutic exercise following total hip arthroplasty for osteoarthritis: A systematic review. by Annet Wijnen, Sjoukje E Bouma, Gesine H Seeber, Lucas H V van der Woude, Sjoerd K Bulstra, Djordje Lazovic, Martin Stevens, Inge van den Akker-Scheek

“…Characteristics of the physiotherapeutic exercise interventions and results about joint and muscle function, functional performance and self-reported outcomes were extracted.…”
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“Text of Culture” as a Category of Cultural Philosophy: from Semiotic Theory to Research Practice by E. N. Shatova

“…The article is of a theoretical and methodological character.Methodology and sources. The methodological basis of the research is the traditions of Russian cultural semiotics and the Tartu-Moscow semiotic school. …”
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Current trends in neurocritical care: a comprehensive review by Vinothini Murugaiyan, Kingston Samraj Kirubakaran Jebaraj, Srinivas Kalaiselvan

“…Continuous neuromonitoring using tools like electroencephalogram and intracranial pressure monitoring offers real-time data on brain function, aiding in the early detection of complications. …”
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Melatonin in the regulation of human life and its role in development pathology by A. V. Shilova, N. I. Ananyeva, N. Yu. Safonova, L. V. Lukina

“…For a detailed analysis, 42 literature sources were selected for the melatonin role in the development of neurological and mental disorders. …”
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