Ecological-environmental consequences of urban sprawl in rural settlements around the Hamedan city by Naser Shafiei Sabet, Sogand Khaksar

“…Introduction: Imposition by cities of new roles and functions on peripheral areas has provoked economic, social and spatial disturbances in those areas (Shafiei Sabet & Bozorgniya, 2013). …”
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QTL analysis for plant height and fine mapping of two environmentally stable QTLs with major effects in soybean by Yu TIAN, Lei YANG, Hong-feng LU, Bo ZHANG, Yan-fei LI, Chen LIU, Tian-li GE, Yu-lin LIU, Jia-nan HAN, Ying-hui LI, Li-juan QIU

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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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The Challenges of Safety Culture: No more risk! by Julija Melnikova

“…These factors by themselves are the definite source of disaster. People are not able to avoid their impacts: different crashes, accidents, fires. …”
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Demand and Influencing factors for community health services during chemotherapy of patients with advanced cancer by Qianqian Li, Xunrui Chen, Wenying Zhang, Haihua Yuan, Yanjie Zhang, Bin Jiang, Feng Liu

“…Logistic regression analysis showed that educational level and disposable monthly household income significantly influenced psychological demand, while age and source of medical expenses influenced medical care demand, and age and patient group participation affected social support demand (P < 0.05). …”
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Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation by Hongyan Xu, Hongyan Xu, Guocai Han, Yanyan Li, Qing Meng, Qing Meng, Yang Zhang, Yayi Wang, Songling Li

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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c... by Ming Zhang, Yani Su, Pengfei Wen, Xiaolong Shao, Peng Yang, Peng An, Wensen Jing, Lin Liu, Zhi Yang, Mingyi Yang

“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. The m6aCRLncs linked to EC were identified through co-expression analysis. …”
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Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad... by Fernanda Ginani, Diego Moura Soares, Carlos Augusto Galvão Barboza

“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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Targeting hyperlipidemia: A polarity-driven ternary extraction of Apium graveolens bioactives—A coupled in-vivo, in-vitro and in-silico investigation by Nargis Sultana Chowdhury, Tasnuva Sharmin Zaman, Rifah Noor Chowdhury, Md Abdur Rahman, Sheikh Rakibul Alam, Romana Akter, Md. Nazmus Samdani, Syeda Sadia Afrin, Md. Rafat Tahsin, Fahima Aktar, Ishrat Jahan, Nasiba Binte Bahar, Salehuddin Ayubee, Umme Habiba Ria, Md Zakir Sultan, Mohammad Borhan Uddin, Jakir Ahmed Chowdhury, Md. Selim Reza, Abu Asad Chowdhury, Shaila Kabir, Md. Shah Amran

“…The findings of the in-silico studies revealed that the 3 top performing compounds (i.e. apiumoside, apiin and graveobioside B) showed high binding affinity to selected anti hyperlipidemic targets HMG CoA reductase and peroxisome proliferator-activated receptor-Alpha (PPAR-Alpha) with a very stable condition in the molecular dynamic simulation against the selected targets. …”
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Transcriptome-wide identification and systematic analysis of the Retrotransposon genes and their roles in ginsenoside biosynthesis in Panax ginseng by Chaofan Wang, Ruicen Liu, Dinghui Wang, Li Li, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang

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Environmental Levels and Degradation Behavior of Pharmaceuticals and Personal Care Products (PPCPs) in the Water Environment by Zhaohe ZHANG, Dian CHEN, Wei ZHAO, Guoli YUAN, Jun LI, Xingchun JIAO

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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…One of the most important indicators that can be used to attract bank resources and assess how to use resources (optimal allocation of resources) and incomes, is the productivity index in the discussion of management quality. …”
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Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement by Sen Luo, Xi Zhou, Meijing Wu, Gongxin Wang, Li Wang, Xujun Feng, Hang Wu, Ren Luo, Minjuan Lu, Junxian Ju, Wenxing Wang, Lei Yuan, Xiaoqing Luo, Dezheng Peng, Li Yang, Qingfeng Zhang, Minzhi Chen, Songping Liang, Xiuming Dong, Guoliang Hao, Yunxiao Zhang, Zhonghua Liu

“…Spider venom‐derived peptide toxins are recognized as significant sources of Nav1.7 inhibitors. However, their development has been impeded by limited selectivity. …”
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Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification by Li Li, Yuezhou Wang, Yiqiu Wang, Xiaoyang Li, Qihong Deng, Fei Gao, Wenhua Lian, Yunzhan Li, Fu Gui, Yanling Wei, Su-Jie Zhu, Cai-Hong Yun, Lei Zhang, Zhiyu Hu, Qingyan Xu, Xiaobing Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Fei Xia, Xianming Deng

“…Homo- or heterodimeric compounds that affect dimeric protein function through interaction between monomeric moieties and protein subunits can serve as valuable sources of potent and selective drug candidates. …”
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eDNA Metabarcoding Reveals the Depth-Structured Variation of Coral Reef Fish by Jinfa Zhao, Lin Lin, Yong Liu, Teng Wang, Yu Liu, Yayuan Xiao, Jianzhong Shen, Hongyu Xie, Hai Huang, Qiuying Han

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Comparison of Fuzzy-AHP and ANP Decision Making Methods to Assess the Ecological Capability of Ecotourism Application (Case study: Dehloran National Natural Monuments) by Mohsen Tavakoli

“…Then, to combine the layers, the model of overlapping index or linear weight composition was used. 3-Results and Discussion Using the GIS on the slope of the linear reduction subscription function, the trajectory linear membership function layer and the temperature layer, an incremental linear membership function was applied. …”
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An Interdisciplinary Ecosystem for the Prevention of Cardiotoxicity in Older Patients With Breast Cancer: Protocol for a Prospective and Multicentric Study by Gaia Giulia Angela Sacco, Ketti Mazzocco, Anastasia Constantinidou, Andri Papakonstantinou, Davide Mauri, Grigorios Kalliatakis, Manolis Tsiknakis, Domen Ribnikar, Dorothea Tsekoura, Valantis Aidarinis, Kalliopi Keramida, Panagiotis Oikonomopoulos, Athos Antoniades, Cameron Brown, Federica Rizzi, Anca Bucur, Elsa Pacella, Georgia Karanasiou, Daniela Cardinale, Carlo Cipolla, Elisabetta Munzone, Dimitrios Fotiadis, Giuseppe Curigliano, Gabriella Pravettoni

“…In total, 750 older patients with breast cancer (aged ≥60 years) are assigned to either the standard practice or enhanced monitoring group, with only patients in the latter receiving access to eHealth psychological, behavioral, and functional interventions implemented on the CARDIOCARE eHealtHeart app. …”
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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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