Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases by He Lu, Yaohui Jiang, Rui Luo, Dexing Zhou, Feihu Zheng, Liran Shi, He Zhang, Yong Wang, Xiaodong Xu, Renfang Zou, Yujing Zhou, Shuai Ren, Xiaocheng Wang, Haiqiang Sang

“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
Get full text

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion by Xuhao Zhang, Yu Gao, Huiping Liao, Wenyan Wang, Zaili Yang, Weian Cao, Ge Li, Jing Wen, Gencheng Han, Yang-Xin Fu

“…Progressive loss of IL2-secretion is an early sign of diminished effector function in TILs, which raises the possibility of IL2 loss driving exhaustion of TILs. …”
Get full text

Differential efficacy of olfactory neurospheres from deviated nasal septum and chronic rhinosinusitis patients in regenerating olfactory epithelium by Rong-San Jiang, Chiang-Wen Lee, Yu-Hsuan Lin, Jing-Jie Wang, Jia-Bin Liao, Kuo-Ti Peng, Yao-Chang chiang, Pei-Ling Chi

“…Conclusions These findings highlight the importance of selecting the appropriate ONS source for therapeutic applications, with DNS-ONS showing greater promise for olfactory epithelium repair and olfactory function restoration.…”
Get full text

Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

Get full text

Validation of the inadequate delivery of oxygen index in an adult cardiovascular intensive care unitCentral MessagePerspective by Heather Holman, BS, Dimitar Baronov, PhD, Jeff McMurray, MD, Arman Kilic, MD, Marc Katz, MD, Sanford Zeigler, MD

“…Conclusions: The IDO2 index is capable of detecting SvO2 ≤50% with good discriminatory function in non-MCS CVICU patients in a variety of monitoring situations. …”
Get full text

Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§ by Nita Kaushik, Aradhita Barmanray

“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
Get full text

Vitamin D and Osteoporosis in HIV/HCV Coinfected Patients: A Literature Review by Paola Di Carlo, Lucia Siracusa, Giovanni Mazzola, Piero Colletti, Maurizio Soresi, Lydia Giannitrapani, Valentina Li Vecchi, Giuseppe Montalto

“…The final 12 articles selected are homogeneous in terms of age but heterogeneous in terms of sample size, participant recruitment, and data source. …”
Get full text

Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…All the patients underwent chest computed tomography (CT). When detecting CT changes, we performed fibrobronchoscopy (FBS) with microbiological examination of bronchoalveolar lavage (BAL).Results. …”
Get full text

Biomechanical Changes to the Ankle After Zadek Osteotomy by Nicholas Bellas MD, Raghunandan Nayak BS, Mehreen Pasha BS, Megan R. Wolf MD, Elifho Obopilwe MS, Thomas McDonald MD, Lauren E. Geaney MD

“…Category: Hindfoot; Sports Introduction/Purpose: Insertional Achilles tendinopathy is a common source of heel pain in active adults and athletes. …”
Get full text

Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach by Zhengyuan Su, Huadong Jiang, Ying Yang, Xiangqing Hou, Yanli Su, Li Yang

“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
Get full text

Estimating the mass of tephra accumulated on roads to best manage the impact of volcanic eruptions: the example of Mt Etna, Italy by L. Mereu, L. Mereu, M. Stocchi, M. Stocchi, A. Garcia, M. Prestifilippo, L. Sandri, C. Bonadonna, S. Scollo

“…First, we analysed a sequence of 39 short-lasting and intense lava fountains detected by the X-band weather radar, applying a volcanic ash radar retrieval approach that permits us to compute the main eruption source parameters (ESPs), such MER, <span class="inline-formula"><i>H</i>_TP</span>, and GSD. …”
Get full text

The TRPA1 cation channel is upregulated by cigarette smoke in mouse and human macrophages modulating lung inflammation by Anita Steib, Katalin Rozmer, Éva Szőke, József Kun, Nelli Farkas, Diána Feller, Judit Pongrácz, Krisztina Pohóczky, Zsuzsanna Helyes

“…The transient receptor potential ankyrin 1 (TRPA1), a smoking-responsive, non-selective cation channel, is expressed by both capsaicin-sensitive peptidergic sensory nerves and non-neuronal cells of the lung, but there are few and controversial data on its expression and function on macrophages. …”
Get full text

The association between serum albumin–globulin ratio and overactive bladder in American adults: a cross-sectional study by Yuan-Zhuo Du, Jia-Hao Liu, Fu-Chun Zheng, Qiang Zhou, Ju Guo

“…However, despite its widely studied correlations in numerous health fields, the link between AGR and Overactive Bladder (OAB) is still not completely comprehended. Methods Data were sourced from the National Health and Nutrition Examination Survey (NHANES) database, selecting adult samples spanning from 2007 to 2018. …”
Get full text

Application of artificial intelligence in echocardiography from 2009 to 2024: a bibliometric analysis by Yangli Liu, Lei Zhao, Bin Tu, Jie Wang, Yaqun He, Rufang Jiang, Xiaofeng Wu, Wen Wen, Jian Liu

“…The objective of this study is to explore the current status and prevailing research trends in this field from 2009 to 2024 through bibliometric analysis and to forecast future developmental trajectories.MethodsWe selected the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WOSCC) as our primary data source and conducted a comprehensive search encompassing all articles and reviews published between 2009 and 2024 and used the online analysis platform of bibliometrics, CiteSpace and VOSviewer software to analyze countries/regions, institutions, authors, keywords, and references, used Microsoft Excel 2021 to visualize the trends of the number of articles published by year.ResultsBetween 2009 and 2024, a total of 3,411 publications on AI applications in echocardiography were identified, including 3,000 articles (87.9%) and 411 reviews (12.1%), contributed by researchers from 100 countries/regions. …”
Get full text

The evolution and competitive strategies of Akkermansia muciniphila in gut by Ji-Sun Kim, Se Won Kang, Ju Huck Lee, Seung-Hwan Park, Jung-Sook Lee

“…In addition, WapA and anSME, which function in competition and post-translational modification of sulfatase, respectively, have been a particularly important selective pressure in the evolution of group A. …”
Get full text

Utilization of Garcinia mangostana L. Peel as an Immunomodulator to Improve the Quality of Human Resources: A Systematic Review by Yunita Satya Pratiwi, Dina Mustika Rini, Ifwarisan Defri, Tawaffani Qubra, Nadien Mutia Intan Maulidi

“…Background: Mangosteen (Garcinia mangostana L.) is recognized for its immunomodulatory properties, which can rejuvenate, regulate, and modulate immune system function. As a rich source of antioxidants, mangosteen peel has the potential to enhance immune responses and improve overall health status. …”
Get full text

Influence of suturing material on wound healing: Experimental study in dogs by Gazivoda Dragan, Pelemiš Dejan, Vujašković Goran, Đurđević Slaviša

“…When using resorbable materials it is of great importance to determine whether its absorbability and tensile strength help wound healing in function of time. Sutures themselves can become a source of inflammation, that may reduce or compromise the potential of reparation and regeneration. …”
Get full text

Enhancing the socio-cultural valuation of ecosystem services in Mountain animal production: a case study from piedmont’s alpine valley (North-west Italy) by Chiara Costamagna, Valentina Maria Merlino, Danielle Borra, Lorenzo Baima, Paolo Cornale, Luca Maria Battaglini

“…The new principal components were employed to cluster the sample in the function of individuals’ perceptions of ecosystem services. …”
Get full text

Efficacy of Anti-VEGF/VEGFR Agents on Animal Models of Endometriosis: A Systematic Review and Meta-Analysis. by Shuangge Liu, Xiaoyan Xin, Teng Hua, Rui Shi, Shuqi Chi, Zhishan Jin, Hongbo Wang

“…Subgroup analyses were performed to determine the source of heterogeneity in endometriosis scores and follicle numbers.…”
Get full text

Toward Sustainable Agriculture: DPA-UNet for Semantic Segmentation of Landscapes Using Remote Sensing Imagery by J. Kavipriya, G. Vadivu

“…Attention gates are also included into the decoder path to selectively hone feature maps from the encoder to emphasize spatially relevant areas during the upsampling process. …”
Get full text