Comprehensive Phenotypic Characterization and Genomic Analysis Unveil the Probiotic Potential of <i>Bacillus velezensis</i> K12 by Yingying Tang, Tian Li, Yihong Huang, Liangliang Wu, Xiaobo Liu, Ruichao Yue, Jianmin Yuan

“…The complete genome sequencing of <i>B. velezensis</i> K12 revealed a genomic length of 3,973,105 base pairs containing 4123 coding genes, among which 3973 genes were functionally annotated. The genomic analysis identified genes associated with acid and bile tolerance, adhesion, antioxidants, and secondary metabolite production, whereas no functional genes related to enterotoxins or transferable antibiotic resistance were detected, thereby confirming the probiotic properties of <i>B. velezensis</i> K12. …”
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Subclinical Aortic Root Pathology in Close Relatives of Patients with Bicuspid Aortic Valve by Ivaniv Y., Lozynska N., Ivaniv I.

“…According to various sources, among the relatives of the first degree (FDR) of affinity the prevalence of BAV is 9.0-21.0%. …”
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Fish Diversity Patterns in Rivers Receiving Ecological Water Supplement Driven by Riparian Land Use by LIU Han, LI Lu-dan, GUO Wei-jie, QIAO Qiang-long, GONG Dan-dan, DU Qi, LI Hang, ZHAO Wei-hua

“…Functional dispersion (FDis) and taxonomic diversity (Delta) correlating significantly with all diversity dimensions (r=0.36-0.90; p&lt;0.05) and outperforming species richness in detecting environmental responses. …”
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Harnessing Hemp (<i>Cannabis sativa</i> L.) Seed Cake Proteins: From Concentrate Production to Enhanced Choux Pastry Quality by Tatiana Capcanari, Eugenia Covaliov, Cătălina Negoița

“…This study explores the production and valorization of hemp seed cake protein concentrate (HPC) as a functional ingredient to enhance the nutritional quality and sensory attributes of choux pastry products, specifically éclairs. …”
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The TOR kinase pathway is relevant for nitrogen signaling and antagonism of the mycoparasite Trichoderma atroviride. by Rossana Segreto, Hoda Bazafkan, Julia Millinger, Martina Schenk, Lea Atanasova, Maria Doppler, Christoph Büschl, Mélanie Boeckstaens, Silvia Soto Diaz, Ulrike Schreiner, Fabiano Sillo, Raffaella Balestrini, Rainer Schuhmacher, Susanne Zeilinger

“…Here we describe how alteration of the activity of TOR1, the single and essential TOR kinase of T. atroviride, by treatment with chemical TOR inhibitors or by genetic manipulation of selected TOR pathway components affected various cellular functions. …”
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Transcriptional profiling of nitrogen fixation and the role of NifA in the diazotrophic endophyte Azoarcus sp. strain BH72. by Abhijit Sarkar, Barbara Reinhold-Hurek

“…Moreover, the NifA regulon in strain BH72 appears to encompass a wider range of cellular functions beyond the regulation of nif genes.…”
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Staged approach to bilateral severe carotid stenosis: a case report and literature review by Heitor Cabral Frade, Manmeet Kaur, Julia Aigbogun, Muhammad Zeeshan Memon, Arun Chhabra, Akm Muktadir, Hashem Shaltoni

“…Hyperperfusion syndrome (HPS), with or without associated intracerebral hemorrhage, although rare, is a major source of morbidity and mortality after carotid interventions, especially in the setting of bilateral CAD. …”
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Range Space and Similarity Transformation Using Symbolic Mathematics in Python by Chainarong Wisassakwichai, Prasert Phaochoo

“…The effectiveness of these classes has been validated through numerical results, which, when compared to MATLAB functions (null(), pinv(), sym(), and jordan()), demonstrate that the exact symbolic solutions from both classes significantly improve numerical precision for selected application examples from numerical algorithms, power systems and linear algebra. …”
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Comparative Analysis of Hydration Status and Microbial Quality of Tap Water Between Urban and Rural Settings in the Ashanti Region of Ghana by Marina A. Tandoh, Priscilla Owusu, Claire-Rush N. A. Nkrumah, Veronica Tawiah Annaful, Chris Y. Asare, Samuel Selorm Attu

“…Six taps were randomly selected at each site in triplicates, resulting in 36 water samples. …”
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Design and Testing of a Small-Scale Composting Facility for Sheep Manure Utilizing Aeration and Thermal Treatment by Jian Wang, Kailin Ren, Longfei Zhang

“…This unit, tailored for small farms and individual farmers, integrates critical functions such as ventilation, heating, and turning. …”
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Mapping and Spatial Analysis of the Development of the Administrative Borders of Stavropol Region in 1785–2021 by Igor Yurievich Katorgin, Alexander Nikolaevich Roman

“…Geoinformation technologies allow processing, spatial coordination of digitized old maps with optimal accuracy, creation of thematic layers necessary for spatial analysis and visualization of the results of work in the form of a series of maps displaying the ATD of the Stavropol region for different periods of development history.Materials and research methods. As the main source of spatial data, old maps were used, selected according to 12 stages of the development of the Stavropol region ATD system over a 237-year period. …”
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Insights on comprehensive characterization of distinct growth stages of Sterculia foetida pod as a potential feedstock for bioethanol production by Saroja Pasupathi, Sameeha Syed Abdul Rahman, Sugumaran Karuppiah

“…Abstract Lignocellulosic biomass explores a sustainable and renewable energy source that could provide a suitable solution to energy demands. …”
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Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry by Safaa Salah El-Din Taha, Osama Abd El-Hamid Ibrahim, Einas Hamed El-Shatoury, Amany Mohamed El-Deeb, Hayam Abd El-Naby Sayed

“…A peak β-galactosidase activity of 5.523 U/ ml was recorded at a pH 7, a lactose concentration of 4.6 %, UF-cheese permeate serving as a carbon source, 2 % potassium nitrate (KNO₃) as a nitrogen source, an inoculum size of 5%, and incubated at 37 ºC for 24 h. …”
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Camellia sinensis phytochemical profiling, drug-likeness, and antibacterial activity against gram-positive and gram-negative bacteria: in vitro and in silico insights by Farouk Boudou, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, David Cornu, Mikhael Bechelany, Mikhael Bechelany, Ahmed Barhoum, Ahmed Barhoum

“…Drug-likeness modeling indicated favorable profiles for most compounds, although EGCG violated Lipinski’s rule due to its molecular weight (458.4 g/mol). Density Functional Theory analysis revealed significant variations in electronic properties among the selected compounds, with quercetin exhibiting the smallest HOMO-LUMO gap (2.31 eV), suggesting high reactivity. …”
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Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…Specifically, we obtain the Rossby number Ro as a function of planetary depth and orbital period, after showing that tidal synchronization is likely valid for all HJs. …”
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Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment by Andrew McGarry, MD, Oliver Roesler, PhD, Jackson Liscombe, PhD, Michael Neumann, PhD, Hardik Kothare, PhD, Abhishek Hosamath, MBM, Lakshmi Arbatti, MS, Anusha Badathala, MD, Stephen Ruhmel, BS, MPH, Bryan J. Hansen, PhD, Madeline Quall, BA, Sandrine Istas, MBio, Arthur Wallace, MD, PhD, David Suendermann-Oeft, PhD, Vikram Ramanarayanan, PhD, Ira Shoulson, MD

“…A complementary approach using digital biomarkers to surpass exam-based limitations for detecting physical change coupled with a direct report from participants on what their sources of suffering are could be a useful advance in reporting beneficial effects of interventions, particularly if changes track together. …”
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MSC-derived extracellular vesicles: Precision miRNA delivery for overcoming cancer therapy resistance by Ahsas Goyal, Muhammad Afzal, Kavita Goyal, Subbulakshmi Ganesan, Mukesh Kumari, S. Sunitha, Aniruddh Dash, Suman Saini, Mohit Rana, Gaurav Gupta, Haider Ali, Ling Shing Wong, Vinoth Kumarasamy, Vetriselvan Subramaniyan

“…The focus is shifting towards employing miRNA-encapsulated exosomes sourced from MSCs to target and heal cancerous cells selectively. …”
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Transforming Bone Tunnel Evaluation in Anterior Cruciate Ligament Reconstruction: Introducing a Novel Deep Learning System and the TB-Seg Dataset by Ke Xie, Mingqian Yu, Jeremy Ho-Pak Liu, Qixiang Ma, Limin Zou, Gene Chi-Wai Man, Jiankun Xu, Patrick Shu-Hang Yung, Zheng Li, Michael Tim-Yun Ong

“…Evaluating bone tunnels is crucial for assessing functional recovery after anterior cruciate ligament reconstruction. …”
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