Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment by Andrew McGarry, MD, Oliver Roesler, PhD, Jackson Liscombe, PhD, Michael Neumann, PhD, Hardik Kothare, PhD, Abhishek Hosamath, MBM, Lakshmi Arbatti, MS, Anusha Badathala, MD, Stephen Ruhmel, BS, MPH, Bryan J. Hansen, PhD, Madeline Quall, BA, Sandrine Istas, MBio, Arthur Wallace, MD, PhD, David Suendermann-Oeft, PhD, Vikram Ramanarayanan, PhD, Ira Shoulson, MD

“…A complementary approach using digital biomarkers to surpass exam-based limitations for detecting physical change coupled with a direct report from participants on what their sources of suffering are could be a useful advance in reporting beneficial effects of interventions, particularly if changes track together. …”
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Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study by Tinkara Srnovršnik, Bojana Pinter, Milena Horvat, Janja Snoj Tratnik, Ingrid Falnoga, Darja Mazej, Ivan Verdenik, Irma Virant-Klun

“…<b>Results:</b> In women with PCOS, lower Mo levels in whole blood (<i>p</i> = 0.024) and serum (<i>p</i> = 0.011) and higher serum Cu levels (<i>p</i> = 0.026) were detected when compared to healthy controls. Results of this study show that amendments in Cu and Mo levels might be related to altered kidney and liver function and disrupted hormonal balance in PCOS women. …”
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Comprehensive Phenotypic Characterization and Genomic Analysis Unveil the Probiotic Potential of <i>Bacillus velezensis</i> K12 by Yingying Tang, Tian Li, Yihong Huang, Liangliang Wu, Xiaobo Liu, Ruichao Yue, Jianmin Yuan

“…The complete genome sequencing of <i>B. velezensis</i> K12 revealed a genomic length of 3,973,105 base pairs containing 4123 coding genes, among which 3973 genes were functionally annotated. The genomic analysis identified genes associated with acid and bile tolerance, adhesion, antioxidants, and secondary metabolite production, whereas no functional genes related to enterotoxins or transferable antibiotic resistance were detected, thereby confirming the probiotic properties of <i>B. velezensis</i> K12. …”
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Subclinical Aortic Root Pathology in Close Relatives of Patients with Bicuspid Aortic Valve by Ivaniv Y., Lozynska N., Ivaniv I.

“…According to various sources, among the relatives of the first degree (FDR) of affinity the prevalence of BAV is 9.0-21.0%. …”
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Neonatal Microcephaly and Central Nervous System Abnormalities During the Zika Outbreak in Rio de Janeiro by Marlos Melo Martins, Roberto de Andrade Medronho, Carlos Eduardo Raymundo, Arnaldo Prata-Barbosa, Antonio José Ledo Alves da Cunha

“…Ophthalmologic abnormalities were detected in 55.5% of cases, and brainstem auditory evoked potential anomalies were reported in 33.3%. …”
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Distorting Electrical Power of the Alternating Current in the Simplest Circuit with a Diode by O. V. Bialobrzheskyi, D. Y. Rod`kin

“…For the analysis of processes of formation the components of electrical power, a diagram of the simplest circuit containing a series-connected source of electromotive force, resistors and a diode is considered; also, the circuit was conditionally separated into a source and a consumer. …”
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Fluorescent robust photoactuator via photo-crosslinking induced single-layered janus polyimide by Shuyu Xue, Zhipanxin Shi, Zaiyu Wang, Haozhe Tan, Feng Gao, Zicong Zhang, Ziyue Ye, Shifeng Nian, Ting Han, Jianbo Zhang, Zheng Zhao, Ben Zhong Tang, Qiuyu Zhang

“…Then the fluorescent robust photoactuators with single-layered janus structure were directly obtained via UV assisted photo-crosslinking of the films, exhibiting reversible response driven by a pronounced mismatch in expansion between the front and back sides of the films. Achieving selective, non-uniform spatial distribution within the PI films, rapid and reversible complex morphing of the actuators, along with the capabilities for encrypting, reading, and erasing fluorescent information—all through the use of a single UV light source—becomes straightforward. …”
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Microbiome Migration from Soil to Leaves in Maize and Rice by Jiejia Ma, Qianze Peng, Silu Chen, Zhuoxin Liu, Weixing Zhang, Chi Zhang, Xiaohua Du, Shue Sun, Weiye Peng, Ziling Lei, Limei Zhang, Pin Su, Deyong Zhang, Yong Liu

“…This indicated that plants can selectively assemble microbiomes from a shared microbiota source. …”
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Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain by Yeojin Kim, Aleksandar Lučić, Christopher Lenz, Frederic Farges, Martin P. Schwalm, Krishna Saxena, Thomas Hanke, Peter G. Marples, Jasmin C. Aschenbrenner, Daren Fearon, Frank von Delft, Andreas Krämer, Stefan Knapp

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German Colonists of Northwest Russia in Conditions of Post-Revolutionary Reality (1918-1922) by V. N. Shaidurov, V. A. Lomanov

“…The condition and functioning of German farms largely depended on the extraordinary revolutionary economic measures carried out by the Bolsheviks within the framework of equalizing land use and “war communism”, where the German village was considered as an easily accessible and high-performance source of agricultural resources for the Red Army and the urban population, which resulted in an excessively high economic burden on the colonies and a selective approach to accounting for national the specifics of the economic life of the Germans and their current economic opportunities. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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Iterative approach for photonic crystal devices design by Pavel V. Mokshin, Dimitriy L. Golovashkin, Vladimir S. Pavelyev

“…The proposed approach differs from known general-purpose optimization methods (e.g., genetic algorithm or gradient procedures) by using diffraction pattern information at different frequencies while optimizing an element designed to operate at the selected wavelength. The design of functional PhC structures with expected characteristics (for example, waveguides) for a certain wavelength (albeit given by a monochromatic radiation source) is described. …”
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Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…Nevertheless, methods based on additional information sources (like further sensors or meteorological data) are also discussed. …”
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Metaphorics and intertexts in the key text positions of political media discourse by V. O. Pareshneva

“…Metaphorical models of implementing the manipulative and predictive functions of the title viewed as a strong position of the text are considered as complex formations including intertextuality and precedent elements. …”
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Isolation and Screening of Phosphate and Potassium Solubilizing Endophytic Bacteria in Maize (Zea mays L.) by Hilya Azizah, Saptini M. Rahajeng, Yoga D. Jatmiko

“…Maize (Zea mays L.) is a functional food source in Indonesia after rice and wheat. …”
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Accumulation of long-chain unsaturated fatty acids in the airway inflammatory microenvironment drives eosinophil etosis and corticosteroid resistance by Yurong Bai, Pengda Fang, Shasha Li, Zhenhao Xiao, Wenyi Chen, Wenlong Li, Xinyue Wang, Jingyuan Chen, Yue Li, Junhai Chen, Weiqiang Huang, Xin Luo, Shigeharu Ueki, Deyu Fang, Qintai Yang, Yana Zhang

“…Functional analyses were performed on purified eosinophils. …”
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes by Praveen Patel, Rory Collins, Richard Peto, Mark Davies, Sanjiv Banerjee, David Simpson, John Anderson, Louise Bowman, Peter Scanlon, Amanda Adler, Andrew Farmer, Helen Cook, Laura Evans, Elizabeth Williamson, Louis Bolter, Jane Armitage, Peter Sandercock, Richard Gray, Nilesh Samani, Tasso Gazis, Richard Haynes, Arun Sachdev, Eric Wu, Elizabeth Wincott, Peter Sleight, Colin Baigent, Marion Mafham, Sarah Parish, Gavin Brown, Susan Hurley, Lynne Allsop, William Stevens, Theingi Aung, Allen Young, Emily Sammons, Georgina Buck, Imen Hammami, Jill Barton, Jonathan Bodansky, Roger McPherson, Lucy Fletcher, Murphy Kevin, Ryonfa Lee, Sandra Pickworth, Monica Willett, Michael Lay, Ola Murawska, Karen Melham, Jonathan Latham-Mollart, Anna Brewer, Mike Olson, Jude Kay, Alisha Griffiths, Helen Clayton, Philip Kirby, Mike Pennington, Dominic Clarke, Jenny Anslow, Alex Hallam, Jenny Witts, Sarah Egan, Alex Wharton, Amy Derbyshire, Katherine Hepplestone, Sujit Mithra, Su Oliver, Pauline Wiatrak-Olszewska, Kelly Alvey, Nick Gregory, Priyai Parkinson, Prema Maharajan, Rachel McFee, Donna Sowter, John Featonby, Richard Furnival, Helen Lipinski, Hazel Benjamin, Tanisha McAfee, Emma Payne Payne, Liz Still

“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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Decoupling of the onset of anharmonicity between a protein and its surface water around 200 K by Lirong Zheng, Bingxin Zhou, Banghao Wu, Yang Tan, Juan Huang, Madhusudan Tyagi, Victoria García Sakai, Takeshi Yamada, Hugh O'Neill, Qiu Zhang, Liang Hong

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