Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

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Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area by Wang YI, Longjun LIANG, Lichong YAN, Zhihua YAN, Jie CHEN, Wei GAO, Yi LOU, Fuqin YANG, Haiyang HU, Jiawei ZHU

“…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
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Development and Application of a Multi-scale Framework for Evaluating Floodplain Restoration Suitability Based on HEC-RAS by Shuoxing LI, Nanxi WANG, Yan ZHA

“…This research uses a multi-level hierarchical screening method to select indicators at three scales: basin, sub-basin and site. …”
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Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility by Jiao Gong, Huiru Sun, Kaiyuan Wang, Yanhui Zhao, Yechao Huang, Qinsheng Chen, Hui Qiao, Yang Gao, Jialin Zhao, Yunchao Ling, Ruifang Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Sijia Wang, Jiucun Wang, Guoqing Zhang, Shuhua Xu, Feng Qian, Fang Zhou, Huiru Tang, Dali Li, Chinese Pangenome Consortium (CPC), Fritz J. Sedlazeck, Li Jin, Yuting Guan, Shaohua Fan

“…Abstract Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. …”
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Evaluating Factors Affecting Interior Architectural Space Quality to Enhance Spatial Resilience and Human Productivity: An Application of Maslow’s Hierarchy of Needs by Moharam Ghahremani Drvish, Farhang Mozafar, Ceyed bagher Hoseini, Fateme Mahdizadeye seraj

“…On the contrary, in our proposed model, the development of biological and psychological factors that are in accordance with the functional needs is the cause of ensuring the quality of the space, and the response to the mentioned needs through the realization of the quality components of the space, fulfills the resilience in the space. …”
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Integrated care programmes for sport and work participation, performance of physical activities and quality of life among orthopaedic surgery patients: a systematic review with met... by Maurits W van Tulder, Pieter Coenen, Gino M Kerkhoffs, Gerben Hulsegge, Joost G Daams, Rutger C van Geenen, Judith A Huirne, Johannes R Anema, P Paul Kuijer

“…We aimed to assess the effectiveness of integrated care among orthopaedic surgery patients.Design Systematic review with meta-analysis.Data source Medline, EMBASE and CINAHL (until 17 June 2019).Eligibility for selecting studies We searched for controlled studies on integrated care interventions consisting of active referral to case managers, rehabilitation with participation-based goals and/or e/mHealth, with outcomes of sports and work participation, performance of physical activities and/or QoL. …”
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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

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Exploring causal relationships between brain imaging-derived phenotypes and ovarian cancer risk: a bidirectional Mendelian randomization by Ting Liu, Xiaoqian Tuo, Huifang Zhao, Yan Wang, Yu Jiang, Jiaojiao Lu

“…We selected single nucleotide polymorphisms (SNPs) as instrumental variables based on rigorous criteria. …”
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Price transmission and market integration analysis of black gram (urad dal) across major Indian states by Sukhvir Singh, Amit Guleria, Parvender Sheoran, Pankaj Sood, Vishal Mahajan, Dharminder Kumar, Satbir Singh, Gurdeep Singh, Rajesh K. Rana

“…BackgroundBlack gram (Vigna mungo), a key pulse crop in India, serves as a major protein source with significant health benefits. Predominantly grown in Madhya Pradesh, Uttar Pradesh, and Rajasthan, its cultivation in Punjab remains limited due to the paddy-wheat dominance. …”
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Meta Analysis of Clustering Nursing for Stroke Associated Pneumonia by Chunyan HAN, Cun ZHAO, Xinglei WANG, Yali CHANG, Li YAO, Yihong KE, Jinhui TIAN, Xinman DOU

“…If the homogeneity between the studies was good (<italic>P</italic>≥0.1, <italic>I</italic>²≤50%), select the fixed effect model, if there was heterogeneity between these studies (<italic>P</italic>&lt;0.1, <italic>I</italic>²&gt;50%), analyze the source of heterogeneity, and if there was no clinical heterogeneity, choose a random effects model.Results:A total of 11 clinical randomized controlled trial literatures were finally included. …”
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Health-Related Messages About Herbs, Spices, and Other Botanicals Appearing in Print Issues and Websites of Legacy Media: Content Analysis and Evaluation by Ann Gaba, Richard Bennett

“…Therefore, legacy media may be considered a credible source of information to readers about these topics.…”
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The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021 by Jian Zhou, Long Gu, Fengling Du, Chun Li, Fan Zhang, Xianhui Zhang, Jinwei Pang, Bingqing Xie, Xiangyu Wang, Jianhua Peng, Yong Jiang

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Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…One-third of the included studies used the leaves of the selected plants. The reviewed studies highlighted neuroprotective activities of the plants, as evidenced by biochemical and behavioral improvements. …”
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Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review by Ukachukwu O Abaraogu, Philippa Dall, Chris Seenan, Sarah Rhodes, Trish Gorely, Joanna McParland, Julie Brittenden, Ebuka M Anieto, Lorna Booth, Cathy Gormal, Jeremy Dearling, Candida Fenton, Sarah Audsley, Kimberley Fairer, Lindsay Bearne, Dawn A Skelton

“…Conclusions The behaviour change technique-based interventions are effective, targeting intention to engage in physical activity, in improving daily physical activity and functional outcomes in the short term, although evidence is limited for maintenance. …”
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The Trend of Residential-Livelihood Changes in Nomadic Ecosystems with Environmental Sustainability Approach (Case Study: Farsimadan Tribe Ecosystem, Fars Province) by Siamak Tahmasbi, Seyed Ali Badri, Mohammad Reza Rezvani

“…In this change, a lot of structures and functions of nomadism have changed. In the past, livestock was impartible components of nomadic life having the value and dignity among nomads and well- known people who had more livestock in the tribe. …”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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High-resolution genetic and physical mapping reveals a peanut spotted wilt disease resistance locus, PSWDR-1, to Tomato spotted wilt virus (TSWV), within a recombination cold-spot... by Dongliang Wu, Chuanzhi Zhao, Walid Korani, Ethan A. Thompson, Hui Wang, Gaurav Agarwal, Jake C. Fountain, Albert Culbreath, C. Corley Holbrook, Xingjun Wang, Josh P. Clevenger, Baozhu Guo

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Health implications of established and emerging stressors: design of the prospective New Jersey Population Health Cohort (NJHealth) Study by Dawne M Mouzon, Paul Duberstein, Joel C Cantor, William T Hu, Stephanie M Bergren, Mara Getz Sheftel, Steven B Cohen, Katherine B Morton, Dinesh Mendhe, Margaret Koller

“…Informed consent is obtained from participants for each source of participant-level data as well as linked administrative and clinical records. …”
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Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress by Lauren A. Hennessy, Bhedita J. Seewoo, Liz A. Jaeschke, Leah A. Mackie, Abbey Figliomeni, Yasmin Arena-Foster, Sarah J. Etherington, Sarah A. Dunlop, Paul E. Croarkin, Jennifer Rodger

“…Behaviour was assessed using the Elevated Plus Maze and Forced Swim Test, and functional, chemical, and structural brain changes measured using magnetic resonance imaging techniques. …”
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