Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…Therefore, the aim of this study was to investigate the function of GJB4 in PC cells and its potential as a therapeutic target.MethodsThe expression of GJB4 in patients with PC was examined using data from The Cancer Genome Atlas (TCGA), The Human Protein Atlas, Gene Expression Omnibus (GEO), Tumor Immune Estimation Resource (TIMER), microRNA Target Prediction Database (miRDB), and Encyclopedia of RNA Interactomes (ENCORI). …”
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The Transjugular Intrahepatic Portosystemic Shunt in the Treatment of Portal Hypertension: Current Status by Gilles Pomier-Layrargues, Louis Bouchard, Michel Lafortune, Julien Bissonnette, Dave Guérette, Pierre Perreault

“…A multidisciplinary approach, including the resources for liver transplantation, is always required to treat these patients.…”
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Assessment of Serum Vitamin D Levels and Evaluation of Knowledge, Attitude, and Practices of Vitamin D Deficiency among Emergency Health-care Workers at a Tertiary Care Center in N... by Sakshi Yadav, Prakash Ranjan Mishra, R. Rajalekshmi, Bharath Gopinath, Praveen Aggarwal, Akshaya Ramaswami, Paulina, Mohit Sharma

“…While most participants were aware of the active form of vitamin D, its sources and critical functions, knowledge about non-skeletal manifestations and measurable forms of vitamin D deficiency was limited. …”
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Common bean processing to obtain a protein ingredient for the plant-based market by Janice Ribeiro Lima, Tatiana de Lima Azevedo, Melicia Cintia Galdeano, Ilana Felberg, Caroline Grassi Mellinger

“…They are naturally rich sources of proteins, ranging from 19% to 24%. This study aimed to define conditions for obtaining protein concentrate from common beans using alkaline extraction with subsequent acid precipitation. …”
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Comprehensive analysis of complete chloroplast genome sequence of Morina L. by Peng-Hui Liu, Qing Yuan, Huan Liu, Le-Le Qin, Yao Wei, Xu-Min Li, Fei Ren, Xiao-Lei Ma, Hai-Rui Liu

“…This study is conducive to the development and utilization of the resources of Morina, and provides a theoretical basis for the further study of this species.…”
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Comparison of enrichment methods for efficient nitrogen fixation on a biocathode by Rous, Axel, Santa-Catalina, Gaëlle, Desmond-Le Quémener, Elie, Trably, Eric, Bernet, Nicolas

“…The first enrichment step was specifically designed for the selection of N2-fixing bacteria from soil samples with organic C as electron and carbon source. …”
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Controllable surface carrier type of metal oxide nanocrystals for multifunctional photocatalysis by Han Li, Yingchun Ding, Kaiyi Luo, Qiuping Zhang, Huan Yuan, Shuyan Xu, Ming Xu

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The Assessment of Utility and the Role of Rural Entrepreneurship Ecosystem in West Azerbaijan Province by ali Gholami, Fatemeh Moohamadzadeh

“…The statistical community of current research includes local experts (such as members of Islamic councils of villages and villagers), which consists of 3108 people. 341 people were selected as the sample by stratified sampling using Cochran method. …”
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Solar‐Powered Hierarchical Microenvironments with Authigenic Multi‐Field Synergies for Simultaneous Extraction of Freshwater and Cesium by Liuyan Zhu, Lin Zhu, Ting Shi, Ke Zhao, Wenwen He, Lu Han, Zeying Jin, Jialin Kang, Shanfu Sun, Ningning Cao, Zhen Yu

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Tradeoffs When Building and Running Cohort and Patient-Level Markov Simulation Models by Balázs Nagy, Ahmad Nader Fasseeh, Jonathan D. Campbell, Zoltán Kaló, Kareem Ahmed El-Fass, Rok Hren, Bertalan Németh

“…The CH and PL models yielded very similar base case results; only minor differences in functionality and outcome consistency were detected. …”
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Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically... by Nessrin Alomran, Jaffer Alsolaiss, Laura-Oana Albulescu, Edouard Crittenden, Robert A Harrison, Stuart Ainsworth, Nicholas R Casewell

“…Despite variability of the immunogen mixtures, both experimental antivenoms exhibited broadly comparable in vitro venom binding and neutralisation profiles against the individual venom immunogens in immunological and functional assays. However, in vivo assessments using a murine preclinical model of antivenom efficacy revealed substantial differences in venom neutralisation. …”
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Integrating Food Preference Profiling, Behavior Change Strategies, and Machine Learning for Cardiovascular Disease Prevention in a Personalized Nutrition Digital Health Interventio... by Hana Fitria Navratilova, Anthony David Whetton, Nophar Geifman

“…Intervention functions were designed using the Behavior Change Wheel, and behavior change techniques were selected for the DHI features. …”
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Bioactive Compounds and Antioxidant Activity of <i>Boletus edulis</i>, <i>Imleria badia</i>, <i>Leccinum scabrum</i> in the Context of Environmental Conditions and Heavy Metals Bio... by Zofia Sotek, Katarzyna Malinowska, Małgorzata Stasińska, Ireneusz Ochmian

“…From a practical perspective, the results highlight the importance of species selection and sourcing location when considering wild mushrooms for consumption or processing, particularly in the context of nutritional value and contaminant load. …”
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Application of modern agronomic and biotechnological strategies to valorise worldwide globe artichoke (Cynara cardunculus L.) potential - an analytical overview by Aneta Grabowska, Gianluca Caruso, Ali Mehrafarin, Andrzej Kalisz, Robert Gruszecki, Edward Kunicki, Agnieszka Sękara

“…The growing importance of globe artichoke as modern functional food as well as a source of pharmaceuticals has raised new issues that all producers have to face; hence the necessity of contemporaneous development of new centres of production and new technologies application in traditional regions of growing which can complement the global market. …”
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YOLOX-LS: Strong Gravitational Lenses Detection in the DECaLS with Deep Learning by Yangyang Liu, Liangping Tu, Jianxi Li, Jiawei Miao, Gengqi Lin, Chenying Zhao

“…We apply the YOLOX algorithm as the basic framework and improve it by selecting the optimal optimizer, activation function, attention mechanism, and loss function. …”
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An 1800 MHz Electromagnetic Field Affects Hormone Levels, Sperm Quality, and Behavior in Laboratory Rats (<i>Rattus norvegicus</i>) by Krzysztof Pawlak, Bartosz Bojarski, Wojciech Jagusiak, Tomasz Wojnar, Zenon Nieckarz, Zbigniew Arent, Magdalena Ludwiczak, Malwina Lasko

“…In addition to natural electromagnetic fields (EMFs), so-called artificial electromagnetic fields exist in the biosphere, with mobile communications being one of their main sources. This study aimed to determine the impact of EMF at a frequency of 1800 MHz on the concentrations of selected hormones, sperm motility, viability, morphology and behaviors in laboratory rats. …”
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Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study by Liu Xiaoyan, Bao Zhongying, Duan Shuhong, Sun Jing, Zhang Yijie, Zhang Jie, Liu Jingxin

“…Emergency department data functioned as an independent external validation set to test the model’s generalizability.ResultsThe study included 1,007 patients, with 778 in the training set and 229 in the validation set. …”
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FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction by Clarissa Tacto, Meghan Tahbaz, Andrew Salib, Shudi Wang, Fritz Cayabyab, Jinhyuk Choi, Kiyoka Kim, Yu Hamba, Harvey Perez, Paul D. Gershon, Robert Damoiseaux, Tae Gyu Oh, Eiji Yoshihara

“…These results suggest that FXYD2 marks and regulates human β cell maturation via channel-sensing signal transduction and that it can be used as a selection marker for functional heterogeneity of stem cell derived human islet organoids.…”
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INFORMATION TECHNOLOGY FOR THE INTEGRATED ASSESSMENT OF EXPERT COMPETENCY by Olena Lobach, Igor Babych, Elena Persiyanova

“…The following results were obtained: the problem of assessing the quality of experts was considered; based on the authors’ practical experience and analysis of literature sources, the structural diagram of the properties of experts and their assessment was developed; five main groups of existing methods for assessing the quality of experts were analyzed; existing models of an integrated assessment of the competency of experts were reviewed; a two-stage method for the integrated assessment of the competency of experts was developed by integrating the methods of heuristic, test, and statistical assessment; the main groups of users and functional requirements to the information system for assessing the competency of experts were identified; the database and user interface of the information system were developed; the developed information technology of the integrated assessment of the competency of experts was tested on actual data for selecting an expert group to choose the methodology of project management. …”
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Correction of Disturbances Influence on Results of Elongated Objects's Probe Microscopy Using Predictive Relief Estimates by P. V. Gulyaev

“…It has been established that control information in the form of forecast estimates can be used in image processing in probe microscopy to detect and partially eliminate disturbances. The formation of predictive images enhances the sharpness of objects and increases the probability of their correct selection using methods based on the analysis of changes in the brightness function.…”
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