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A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles
Published 2025-08-01“…Abstract Extracellular vesicles (EVs) have emerged as sources of promising, minimally invasive biomarkers for diagnosing and monitoring diseases like Alzheimer's. …”
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Growth and Form Trait Variation Analysis Among Different Clones of Michelia chapensis
Published 2025-04-01“…【Method】A total of 213 M. chapensis grafted clones derived from different regions of Guangdong, Hunan, Jiangxi were tested in National Forest Tree Germplasm Resource Bank of Magnoliaceae of Longshan in Guangdong (China) for their growth performance and form traits. …”
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1863
Activity tracking devices in pregnancy: Understanding the participant experience in a longitudinal birth cohort
Published 2025-06-01“…REACH-Fitbit participants had to be <20 weeks gestation with access to a Bluetooth-enabled device. Recruitment (self-selection) for focus groups occurred from completed REACH-Fitbit participants (e.g., delivered their baby). …”
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Bioinformatics analysis to explore biomarkers and mechanisms of action associated with endoplasmic reticulum stress and ferroptosis in Parkinson's disease.
Published 2025-01-01“…Further investigations included functional enrichment analysis, the construction of a protein-protein interaction (PPI) network, and the examination of related genes. …”
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Quantifying degradation in animal acoustic signals with the R package baRulho
Published 2025-03-01“…Abstract Animal acoustic signals are shaped by selection to convey information based on their tempo, intensity, and frequency. …”
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High-quality reference genome decoding and population evolution analysis of prickly Sechium edule
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1867
Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period
Published 2025-08-01“…On each testing day, storage lesion related indicators of red blood cells (RBCs), plasma components, and platelets were respectively detected.ResultsOn the 14th day of CS-WB storage, no significant changes were found in the morphology, quantity, and function of RBCs. …”
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1868
Effect of triclosan on phosphate solubilising bacteria in mangrove ecosystem: In-vitro and In-vivo
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1869
Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin
Published 2025-12-01“…Background Rectal adenocarcinoma (READ) involves the dysregulated expression of alpha 2,8-Sialyltransferase1 (ST8Sia1) although its role during READ’s progression is unclear.Methods The mRNA level of ST8Sia1 was analyzed based on The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Tumor Immune Estimation Resource (TIMER) 2.0. Furthermore, the prognostic and significance of ST8Sia1 in READ was assessed through Kaplan-Meier curve, univariate, multivariate Cox regression, and receiver operating characteristic (ROC) methods. …”
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Pretest probability of coronary artery disease as a factor for optimizing invasive diagnostics in routine clinical practice
Published 2022-02-01“…In 2017-2019, the number of detected CAD cases and proportion of men increased. …”
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Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia
Published 2025-08-01“…It aims to regulate key enzyme genes to develop low-toxic E. sonchifolia resources, integrating metabolomic and transcriptomic approaches to balance medicinal efficacy and safety.…”
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Digital Platforms for the Built Environment: A Systematic Review Across Sectors and Scales
Published 2025-07-01“…Unlike existing reviews focused on single technologies or sectors, this work offers a cross-sectoral synthesis, highlighting shared challenges and opportunities across disciplines and lifecycle stages. It identifies the functional roles, enabling technologies and systemic barriers affecting digital platform adoption, such as fragmented data sources, limited interoperability between systems and siloed organizational processes. …”
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1873
Identification of Suitable Villages for Agritourism Development (A Case Study of Semirom County)
Published 2024-09-01“…The results will be practical for planners and regional officials in selecting a suitable village for investment and agritourism development.…”
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1874
Clinical profile and molecular genetic analysis of alport syndrome in children: a single center experience
Published 2024-12-01“…Genetic testing emerged as a critical resource for diagnosing AS. Furthermore, early diagnosis is crucial for implementing an appropriate management plan and assessing the prognosis.…”
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1875
Peculiarities of the morphology of the fish stomach
Published 2025-03-01“…Histochemical characteristics of the stomach of fish can serve as a theoretical basis for the development of a normal stomach test system for detecting functional changes under the influence of environmental factors.…”
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Long-term dynamics of forage base and food supply for nekton in the upper epipelagic layer of the western Bering Sea. Part 2. Food supply for nekton
Published 2022-04-01“…Summary in the summer-fall periods, the fish and squids consumed 2–5 % of zooplankton production (up to 5–7 % in some years) in the deep-sea basins that is rather low degree of the zooplankton resources usage. In the Navarin area, the consumption is considerably higher and is estimated as 5 % in summer and 21 % in fall season, on average. …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station
Published 2025-04-01“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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