Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…In recent years, broccoli production in Taizhou was frequently affected by these two fungal diseases, resulting in yield and quality loss. Broccoli germplasm resources resistance to disease is scarce; therefore, molecular breeding is regarded as an effective solution to solve the problem. …”
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Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes by Ma L, Zheng E, Fang Y, Chen H, Zhou C, Cai S, Luo F, Jiang W, Wang J, Ning X, Tu H, Yin Z

“…IC spans five function domains: Locomotor, psychological, cognitive, vitality, and sensory (including vision and hearing). …”
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CFD investigation and ANN prediction of heat transfer coefficient for fully developed turbulent air flow around double V-baffle turbulators by Abdulaziz Alasiri, H.E. Fawaz

“…The process of training incorporates the analysis of the loss function on training and validation data for controlling the weights and biases using backpropagation while feed forward propagate the selected input parameters. …”
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A competing risk analysis of predictors of time to lost to follow-up among adults with TB/HIV coinfection in Bahir Dar by Robel Demelash, Getachew Hailu, Taye Abuhay, Zemenu Addis, Ayenew Tega, Degarege Nibret, Yitagesu Habtu

“…Overestimating effect sizes when considering mutually exclusive events, like LTFU from ART and anti-TB treatment, can occur if sources of error are not properly accounted for in competing events. …”
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A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention by You Zhai, Hongcai Shang, Yan Li, Nan Zhang, Jisi Zhang, Shangwen Wu

“…ObjectiveThis study aims to systematically review the risk factors for major adverse cardiovascular events (MACE) in patients with coronary heart disease who have undergone percutaneous coronary intervention (PCI).DesignSystematic review and meta-analysis.Data sourcesThe Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals (VIP) were screened until December 2024.Eligibility criteria for selecting studiesCase-control studies or cohort studies on the risk factors for MACE in patients with coronary heart disease who underwent PCI. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Whole blood RNA-seq analysis reveals the immunomodulatory effects of a supplemental multi-strain direct-fed microbial in the diet of newly weaned beef steers1 by Adekunle Ajiboye, Samanthia Johnson, Modoluwamu Idowu, Yarahy Leal, Taylor Sidney, Godstime Taiwo, Ibukun M. Ogunade, Christopher Ashwell

“…On day 56, 10 mL of blood was collected from 10 randomly selected beef steers from each treatment group prior to morning feeding. …”
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Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda. by Jonathan Kitonsa, Onesmus Kamacooko, Ubaldo Mushabe Bahemuka, Freddie Kibengo, Ayoub Kakande, Anne Wajja, Vincent Basajja, Alfred Lumala, Edward Ssemwanga, Robert Asaba, Joseph Mugisha, Benjamin F Pierce, Robin Shattock, Pontiano Kaleebu, Eugene Ruzagira

“…Data were analysed descriptively and a binomial generalised linear model with a log link function used to investigate factors associated with unwillingness to participate.…”
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Persistence in the socio-economic development of the regions of the Siberian Federal District by Misak S. Arzumanyan

“…The term «persistence» originally has a biological and medical origin, as a property of microorganisms (bacteria, viruses) to survive and function in an aggressive environment (e.g., when exposed to antibiotics). …”
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The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs by Omar T. F. Ahmed, Ziyad Tarek Ahmed, Abdulrahman W. Dairi, Maha Saad Zain Al-Abeden, Mohammed H. Alkahlot, Rana H. Alkahlot, Ghazi I. Al Jowf, Lars M. T. Eijssen, Khawaja Husnain Haider

“…The data were then plotted for various outcomes, including death, hospitalization, major adverse cardiac events, pump function parameters, and 6-min walk distance. Results The safety of MSC-based treatment has been consistently demonstrated with MSCs from autologous (AutoMSCs) and allogeneic (AlloMSCs) sources. …”
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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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State of the art in remote sensing monitoring of carbon dynamics in African tropical forests by Thomas Bossy, Thomas Bossy, Thomas Bossy, Philippe Ciais, Philippe Ciais, Solène Renaudineau, Liang Wan, Bertrand Ygorra, Elhadi Adam, Nicolas Barbier, Marijn Bauters, Nicolas Delbart, Nicolas Delbart, Frédéric Frappart, Tawanda Winmore Gara, Eliakim Hamunyela, Suspense Averti Ifo, Gabriel Jaffrain, Philippe Maisongrande, Maurice Mugabowindekwe, Maurice Mugabowindekwe, Theodomir Mugiraneza, Theodomir Mugiraneza, Cassandra Normandin, Conan Vassily Obame, Marc Peaucelle, Camille Pinet, Pierre Ploton, Le Bienfaiteur Sagang, Martin Schwartz, Valentine Sollier, Bonaventure Sonké, Bonaventure Sonké, Paul Tresson, Aurélien De Truchis, An Vo Quang, Jean-Pierre Wigneron

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Diagnostic potential of the B9D2 gene in colorectal cancer based on whole blood gene expression data and machine learning by Zhaorui Wang, Yongcheng Fu, Haozhe Zhang, Na Liu, Ningjing Lei

“…Additionally, three machine learning methods—Random Forest (RF), LASSO regression, and Support Vector Machine Recursive Feature Elimination (SVM-RFE)—were employed for feature selection and to evaluate the robustness and predictive power of the selected features, with diagnostic efficacy evaluated through Receiver Operating Characteristic (ROC) curves. …”
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Rock Fracture Monitoring Based on High-Precision Microseismic Event Location Using 3D Multiscale Waveform Inversion by Yi Wang, Xueyi Shang, Kang Peng, Rui Gao

“…Results show that the source-time function based on the fractional-order Gaussian function wavelet can better fit complex recording waveforms compared with the conventional Ricker wavelet-based source-time function, and the waveform misfit during the L-BFGS iteration decreased rapidly. …”
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Identification of multiple power quality disturbances in hybrid microgrid using deep stacked auto-encoder based bi-directional LSTM classifier by Ravi Kumar Jalli, Lipsa Priyadarshini, P.K. Dash, Ranjeeta Bisoi

“…Thus to design an effective PQD recognition system, this paper proposes a novel time-frequency analysis method based on adaptively fast complementary ensemble local mean decomposition (AFCELMD) technique that decomposes the multicomponent PQD signal into a series of demodulated product functions (PFs). Out of the several PFs the most sensitive one is selected adaptively and used for feature extraction and classification through a deep stacked auto-encoder (dSAE) hybridized with a time-recursive bi-directional long short term memory (BiLSTM) network classifier. …”
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Construction of a Multi-level Blue-Green Infrastructure Network in a Riverside City: A Case Study of Shaoxing by Meizi Zhou, Yong He, Zhi Qiu

“…To address this gap, this study proposes a framework for constructing a multi-level BGI network. We selected Shaoxing City, a typical riverside city in the Yangtze River Delta region of China, as the study area and integrated water-related ecosystem services into the identification of ecological sources. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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