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1581
Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice
Published 2025-08-01“…A subset of the Plin2-expressing macrophages was identified as a major source of Ifnb1 and Cxcl1, suggesting their involvement in type I interferon signaling and neutrophil recruitment. …”
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1582
The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters
Published 2025-01-01“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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1583
Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis
Published 2024-12-01“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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1584
Open Science Alternatives to Scopus and the Web of Science: A Case Study in Regional Resilience
Published 2024-11-01“…Since scientometric databases were developed in different contexts, they are characterized by structural and functional heterogeneity, which complicates their comparison. …”
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1585
Application of a sEMG hand motion recognition method based on variational mode decomposition and ReliefF algorithm in rehabilitation medicine.
Published 2024-01-01“…In recent years, surface electromyogram (sEMG) signals that directly reflect human motion information are ideal input sources for prosthetic control and rehabilitation. …”
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1586
Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons
Published 2025-03-01“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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1587
Additive Manufacturing for Automotive Radar Sensors Using Copper Inks and Pastes
Published 2025-03-01“…Radar sensors are critical for obstacle detection and navigation, especially for automated driving. …”
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1588
Concept of Vector Multicomponent Physical Quantities, Models and Measurement Method
Published 2022-12-01“…There are three positions of this conception in this paper, which are formulated as follows: vector multicomponent physical quantities are considered as functions of the set of their constituent information components; the communication functions of the specified information components in the models of multicomponent physical quantities are determined by the laws of vector algebra; information models of vector multicomponent physical quantities allow an alternative representation of information components depending on the selected coordinate system.The mathematical model of the vector multicomponent physical quantity is presented. …”
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1589
Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans
Published 2025-04-01“…Our ORNG process releases N-glycans from kilogram-scale of natural sources containing various glycoproteins, which can be efficiently attached with a 4-aminobenzoate tag, facilitating the selective separation of these glycans from other biomolecules. …”
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1590
How much does a disrupted mitochondrial network influence neuronal dysfunction?
Published 2018-12-01“…This ensures all tissues have an adequate energy supply and underlines the need for a fully functional mitochondrial network. Since mitochondrial biogenesis and maintenance require components from two genetic sources, mitochondrial diseases can result from mutations in either the nuclear or the mitochondrial genome (mtDNA). …”
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1591
Pathogenesis of Apical Periodontitis: a Literature Review
Published 2011-09-01“…Additionally, a manual search in the cytokine production, cytokine functions and periapical tissue destruction in the journals and books was performed.Results: In total, 97 literature sources were obtained and reviewed. …”
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1592
Greener solvents in extraction of proteins and peptides
Published 2025-02-01“…The sample pretreatment still represents a fundamental aspect of any analytical workflow, and the implementation of sustainable and efficient extraction of proteins is essential to satisfy the increasing requirements for high-quality extraction of proteins from their natural sources. Proteins, with their unique structural and functional characteristics, are utilized in several industries such as pharmaceuticals, biomedicine, cosmetics, and food. …”
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1593
A Study of the Reflection of Qur'anic Verses in Mihrab Carpets of the Safavid Period
Published 2025-05-01“…And how do the inscriptions relate to the visual motifs and designs? Relying on library sources and image analysis, and using a historical-descriptive method, the research finds that the content of the inscriptions-such as specific verses and dhikr formulas-functions in harmony with the architectural and floral elements of the mihrab-shaped carpets. …”
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1594
Development of the information platform of the station ACS through interaction with the rolling stock identification systems, control complexes for sorting automation and satellite...
Published 2018-04-01“…ASUST facilities combine, analyze and optimize all data flow possible for a given control object, making cross-sections and selections that allow station employees to quickly perform their functional duties. …”
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1595
Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…By integrating them with multiple-source genomic data, we found a PD-associated gene co-expression module, and its alignment with the CMAP database successfully identified drug candidates. …”
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1596
Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05
Published 2024-12-01“…SEM analysis revealed morphological alterations, including cracks and holes, ATR-FTIR detected new functional groups (alcohols, alkynes, aldehydes, alkenes and ketones), while XRD identified changes in the polymer crystallinity and phase composition. …”
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1597
CRISPR-Cas9 and Its Bioinformatics Tools: A Systematic Review
Published 2025-04-01“…This systematic review summarizes the functionality and key features of such tools. Studies published after 2012 were selected through searches in PubMed, Google Scholar, and other sources, with the final search conducted on 9 November 2024. …”
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1598
Systematic Literature Review on the Utilization of Tuber Crop Skins in the Context of Circular Agriculture
Published 2024-05-01“…Method: A rigorous review protocol was applied to analyze 26 articles sourced from ScienceDirect and Web of Science. The selection criteria focused on works that explore the application of tuber crop skins in various domains, ensuring a comprehensive coverage of the subject matter. …”
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1599
Comparing statistical learning methods for complex trait prediction from gene expression.
Published 2025-01-01“…The methods considered differ in assumptions about the distribution of gene effects-ranging from models that assume that every gene affects the trait to more sparse models-and their ability to capture gene-gene interactions. We also used functional annotation (i.e., Gene Ontology (GO)) as a source of biological information to inform prediction models. …”
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1600
Per-Hop Reversed Packet Auctions for Cooperative Routing in Mobile Wireless Networks
Published 2021-01-01“…Previous works on the subject have either tackled cooperation in the relay of messages alone or in both routing and relay functionalities. In the latter case, path selection is usually carried out at the destination node, which renders significant delays because the selected path needs to be conveyed all the way back to the source node before any data packet can be transmitted. …”
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