Near telomere-to-telomere genome assembly of the blackspot tuskfish (Choerodon schoenleinii) by Zhongdian Dong, Jiahao Gao, Yanfei Zhao, Jin Gao, Yusong Guo, Zhongduo Wang, Ning Zhang

“…Notably, telomeres were identified at both ends of 23 chromosomes, with 14 being completely gapless and only 12 gaps detected across the remaining nine. A total of 24,524 protein-coding genes were annotated, with 96.25% assigned functional annotations. …”
Get full text

The cardiac phospho-proteome during pressure overload in mice by Rhys Wardman, Steve Grein, Jennifer Schwartz, Frank Stein, Joerg Heineke

“…Our analysis highlights significant changes in hypertrophic signalling, metabolic remodelling, contractile function, and the stress response pathways. We present proteomic data from the main cardiac cell types (endothelial cells, fibroblasts and cardiomyocytes) to reveal the cellular localisation of the detected phospho-proteins, offering insights into temporal and site-specific phosphorylation events, facilitating the potential discovery of novel therapeutic targets and biomarkers. …”
Get full text

Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics by Salvatore Benfatto, Martin Sill, David T. W. Jones, Stefan M. Pfister, Felix Sahm, Andreas von Deimling, David Capper, Volker Hovestadt

“…We detect a high degree of genomic redundancy, with many genes distinguishing individual tumor classes, explaining the robustness of the classifier and revealing potential targets for further therapeutic investigation. …”
Get full text

Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport by Wang-Jong Lee, Ernest Mazigo, Jin-Hee Han, Seok Ho Cha

“…PvApiAT8 was sodium-independent and functioned at pH levels between 6.5 and 8.5, with no efflux activity observed. …”
Get full text

In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors. by David Gothard, Emma L Smith, Janos M Kanczler, Cameron R Black, Julia A Wells, Carol A Roberts, Lisa J White, Omar Qutachi, Heather Peto, Hassan Rashidi, Luis Rojo, Molly M Stevens, Alicia J El Haj, Felicity R A J Rose, Kevin M Shakesheff, Richard O C Oreffo

“…The proposed hydrogel system functioned without the need for growth factor incorporation or an exogenous inducible cell source. …”
Get full text

Comparative analysis of gut symbionts in Tribolium castaneum (Coleoptera: Tenebrionidae) and their dietary substrate, sauce-flavored Daqu by Jun Lü, Shan Xu, Can Teng, Rujia Huang, Guiqin Xiong, Qin Cheng

“…Shared bacterial ASVs (n=58) exhibited functional divergence: carbohydrate metabolism dominated in SFD, whereas insect-associated ASVs enriched drug resistance genes. …”
Get full text

Chronic low back pain: Evaluation and management by A.R. Last, K. Hulbert

“…A surgical evaluation may be considered for select patients with functional disabilities or refractory pain despite multiple nonsurgical treatments.…”
Get full text

Psycho-Theological Learning Model to Improve Mental Resilience in Muslim Adolescents by Muhammad Zamzam, Winsidi Winsidi

“…The research utilized a qualitative approach with a phenomenological design to explore the lived experiences of Muslim adolescents undergoing such learning. Data were sourced from purposively selected teachers and students actively engaged in faith-based character education programs. …”
Get full text

Hybridization in Metal Wire Additive Manufacturing: A Case Study of an Impeller by Shahu R. Karade, Siddhartha Siddhartha, Neel Kamal Gupta, Ganesan G, K. P. Karunakaran, Henning Zeidler

“…Additive manufacturing (AM) has evolved to enable the direct production of functional components through the hybridization of additive and subtractive processes. …”
Get full text

Growth and Form Trait Variation Analysis Among Different Clones of Michelia chapensis by Zhixi DENG, Baishuan LYU, Rong HUANG, Limin ZHOU, Runhui WANG, Li CHEN, Zhijun LAI, Jiaqi CHEN, Jie ZHU, Ruping WEI, Huiquan ZHENG

“…Significant (P < 0.05) to highly significant (P < 0.01) phenotypic and genetic correlations were detected among the traits (except between tree height and crown-to-diameter ratio). …”
Get full text

Multi-directional deformation for coordinating isotropy and strength-ductility synergy in a CoCrNi alloy by Na Lin, Zhicheng Miao, Mingcan Li, Rumeng Huang, Kaiyuan Zheng, Zhaowen Huang, Donghui Wen, Cong Zhang, Anding Wang

Get full text

Morpho-Molecular and Genomic Characterization of <i>Penicillium mexicanum</i> Isolates Retrieved from a Forsaken Gold Mine by João Trovão, Fabiana Soares, Diana Sofia Paiva, António Portugal

Get full text

An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment by Enzo Romero, Jose G. Garcia, Magno Parra, Sebastian Caballa, Alejandro M. Saldarriaga, Edson F. Luque, Dante J. Rodriguez, Victoria E. Abarca, Dante A. Elias

“…Conventional myoelectric prostheses, while offering functional restoration, have limited adaptability and high cost. …”
Get full text

Suspensory Materials for Surgery of Blepharoptosis: A Systematic Review of Observational Studies. by Elena Pacella, Daniele Mipatrini, Fernanda Pacella, Giulia Amorelli, Andrea Bottone, Gianpaolo Smaldone, Paolo Turchetti, Giuseppe La Torre

“…The following materials were investigated: Fascia Lata, Mersilene, polytetrafluoroethylene (PTFE) and Silicon.<h4>Data source and methods</h4>Following the Prisma procedure, on January 30th, 2016 we used the following electronic databases to select the studies: MEDLINE and Scopus.…”
Get full text

The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging by Hong-Fei Li, Bao Dong, Yuan-Yuan Peng, Hao-Yue Luo, Xiao-Lan Ou, Zheng-Lin Ren, Yoonseong Park, Jin-Jun Wang, Hong-Bo Jiang

“…Further analysis of the mutant flies revealed that sets of odorant receptor (OR) genes were differentially expressed. Functional characterization of the differentially expressed ORs suggested that sulfakinin directly suppresses the expression of ORs that respond to opposite-sex hormones while enhancing the expression of ORs that detect food volatiles. …”
Get full text

Preparation Process Optimization and Physicochemical Properties Characterization of Jinhua Ham Enzymolysis Peptide by Weiqiang WANG, Yu ZHENG, Weimin XU, Yanbo WANG, Jie CHEN

“…To investigate the potential of enzymatic hydrolysis for enhancing the nutritional and functional properties of Jinhua ham, a concentrated extract produced by dialysis desalination was employed as a substrate. …”
Get full text

Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period by Yingyu He, Yiquan Zhang, Wanbing Liu, Lidong Zhang, Yingkai Xu, Zihan Yuan, Junying Li, Lei Liu, Fangxiong Cheng

“…On each testing day, storage lesion related indicators of red blood cells (RBCs), plasma components, and platelets were respectively detected.ResultsOn the 14th day of CS-WB storage, no significant changes were found in the morphology, quantity, and function of RBCs. …”
Get full text

A Transition Metal‐Free Approach for the Conversion of Real‐Life Cellulose‐Based Biomass into Formate by Tong Zhang, Peng Ren, Yuman Qin, Thanh Huyen Vuong, Ana V. Cunha, Remco W. A. Havenith, Jabor Rabeah, Shoubhik Das

“…Finally, mechanistic investigations including electron paramagnetic resonance (EPR) spectroscopy, and density functional theory (DFT) calculations are conducted to gain insights into the underlying reaction mechanism.…”
Get full text

Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation by Takashi Hoshiba, Guoping Chen, Chiho Endo, Hiroka Maruyama, Miyuki Wakui, Eri Nemoto, Naoki Kawazoe, Masaru Tanaka

“…Stem cells are a promising cell source for regenerative medicine. Stem cell differentiation must be regulated for applications in regenerative medicine. …”
Get full text

Analytical Approach to Circulating Current Mitigation in Hexagram Converter-Based Grid-Connected Photovoltaic Systems Using Multiwinding Coupled Inductors by Abdullrahman A. Al-Shamma’a, Abdullah M. Noman, Khaled E. Addoweesh, Ayman A. Alabduljabbar, A. I. Alolah

“…The hexagram multilevel converter (HMC) is composed of six conventional two-level voltage source converters (VSCs), where each VSC module is connected to a string of PV arrays. …”
Get full text