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Suggested Topics within your search.
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2721
Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity
Published 2019-10-01“…Recently, the protein of SRC8 (Sarc family protein kinase substrate or cortactin) was detected among 12 new proteins in urine protein analyzes in breast cancer patients. …”
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2722
Optimizing Nav1.7‐Targeted Analgesics: Revealing Off‐Target Effects of Spider Venom‐Derived Peptide Toxins and Engineering Strategies for Improvement
Published 2024-11-01“…Spider venom‐derived peptide toxins are recognized as significant sources of Nav1.7 inhibitors. However, their development has been impeded by limited selectivity. …”
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2723
A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response
Published 2025-02-01“…Results: The model was successfully established independently from cancer etiology and grade from 22 HCC tissues. …”
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2724
Structural Parameter Identification Using Multi-Objective Modified Directional Bat Algorithm
Published 2025-01-01“…In the Haiwen Bridge application, MOMDBA successfully identified all 14 structural parameters with a maximum relative error of 2.59%. …”
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2725
How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland?
Published 2025-01-01“…Results In the following, a selection of relevant factors that were found are presented. …”
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2726
Representation of the perception of effective factors on the implementation of Eric Cheng's knowledge management model in secondary schools of West Azarbaijan province
Published 2024-09-01“…The purposeful sampling method is of homogeneous type, and based on the principle of data saturation; 8 people were selected as sample managers. In order to collect information, a semi-structured interview was conducted with the participants. …”
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2727
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway
Published 2025-05-01“…Double-labeled immunofluorescence showed eIF3a was mostly co-localized with CD31, this result indicated that the development of MCT-induced PAH was related to the regulation of PAECs function (most likely associated with the change of EndMT in endothelial cells). …”
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2728
Integration of co-culture conditions and 3D gelatin methacryloyl hydrogels to improve human-induced pluripotent stem cells-derived cardiomyocytes maturation
Published 2025-07-01“…Omics analyses were carried out to compare terms of biological processes, cellular components, and molecular functions between the 3D model here presented and a classical 2D monoculture of hiPSC-CMs.ResultsGelMA was successfully synthesized with two different DoMs (i.e., 30%–40% and 96%–97%) and used to prepare hydrogels at 5%, 7.5% and 10% w/v concentrations. …”
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2729
Comparing the Effectiveness of Self-Compassion and Mindfulness Therapies on Affection Control of Poor Parenting Adolescents
Published 2024-11-01“…The sample included 60 adolescents, who were voluntarily taking part in the study. They were selected and categorized in three groups (two experimental and one control) through purposeful sampling method. …”
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2730
Preliminary Study on Natural Infection of Shellfish with Movement Disorder Nodavirus (MDNV)
Published 2025-08-01“…Shellfish is an important source of high-quality protein for human beings and simultaneously plays an important ecological service function in the marine ecosystem. …”
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2731
Effect of the time factor on the hydraulic activity of mechanically activated saponin-containing powder
Published 2025-06-01“…To perform potentiometric analysis, an electrode system consisting of a measuring electrode with a calcium ion detection function (pCa) and a reference electrode was used. …”
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2732
Influence of Emergent Vegetation Layout on Flow Pattern in a Rectangular Shallow Basin
Published 2024-07-01“…Prior research has extensively debated shallow basins’ functions and influencing factors from these perspectives, employing methods such as field investigations, aerial remote sensing, physical experiments, large-scale modeling, and surveys. …”
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2733
Identification of Suitable Villages for Agritourism Development (A Case Study of Semirom County)
Published 2024-09-01“…The results will be practical for planners and regional officials in selecting a suitable village for investment and agritourism development.…”
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2734
Research on Data Repair of Pile-Type Adjustable Wind Turbine Foundation Monitoring Based on FST-ATTNet
Published 2025-01-01“…The Kolmogorov-Arnold Network (KAN) incorporates a B-spline activation function, further enhancing the model's ability to capture complex nonlinear temporal changes. …”
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2735
The Impact of Audit Quality on Organizational Capital and Financing Capacity
Published 2025-12-01“…These results collectively advance our understanding of audit quality's dual function as both an organizational capital enhancer and financial constraint moderator. …”
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2736
Analysis of the Causes of Urban Sprawl in Iran
Published 2024-12-01“…Discussion of Results & ConclusionThe causes of urban sprawl in Iran were categorized into 15 distinct dimensions: city form, urban management and planning, infrastructure and urban elements/transportation, land and housing management, planning, and policy, migration and land preparation, socio-cultural factors, natural factors, economic factors, urban plans, political factors, inner-city problems, marginalization and informal settlement issues, urban peripheral problems, demographic factors, and other factors.Within the dimension of city form, spatial-functional discontinuity was noted as a contributing factor (3 occurrences in the sources). …”
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2737
Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
Published 2025-01-01“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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2738
Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT
Published 2025-04-01“…Work package 4: Development and refinement of a care transitions intervention Intervention development Functional resonance analysis method was used to model the transition process. …”
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2739
Nature-based solutions for urban climate resilience: implementation, contribution, and effectiveness
Published 2025-12-01“…For instance, of the 26 qualitative sample publications selected for this systematic review, almost 54 % employed only secondary data sources, and eight publications lacked clear and specified data analysis techniques. …”
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2740
Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review
Published 2025-05-01“…Conclusions The behaviour change technique-based interventions are effective, targeting intention to engage in physical activity, in improving daily physical activity and functional outcomes in the short term, although evidence is limited for maintenance. …”
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