Suggested Topics within your search.
Suggested Topics within your search.
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3281
Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury
Published 2025-04-01“…This study aims to elucidate the potential molecular interactions between key genes associated with oxidative stress and their influence on TBI pathogenesis.MethodsTBI dataset and oxidative stress-related genes sourced from Public databases. Differential expression analysis and machine learning models were executed to select key genes, which were further validated using receiver operating characteristic (ROC) curves. …”
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3282
Feedback of patient-reported outcomes to healthcare professionals for comparing health service performance: a scoping review
Published 2020-11-01“…Therefore, the aim of this scoping review was to summarise the emerging approaches to PROs data for ‘service-level’ feedback to healthcare professionals.Setting Healthcare professionals receiving PROs data feedback at the health-service level.Data sources Databases selected for the search were Embase, Ovid Medline, Scopus, Web of Science and targeted web searching. …”
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3283
Cell death pathway regulation by fatty acid metabolism-related genes in neuroblastoma: a multi-omics analysis identifying CHD5 as a novel biomarker
Published 2025-03-01“…Abstract Background Neuroblastoma in children is commonly found as an extracranial solid tumor with poor prognosis in high-risk cases impeding successful treatment. While dysregulated cell death mechanisms and metabolic reprogramming are hallmarks of cancer progression, the interplay between fatty acid metabolism and cell death pathway regulation in neuroblastoma remains incompletely understood. …”
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3284
Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov...
Published 2025-07-01“…A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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3285
5-Year Survivorship and Outcomes of Robotic-Arm-Assisted Medial Unicompartmental Knee Arthroplasty
Published 2022-01-01“…Robotic-arm-assisted UKA (RA-UKA) has shown to be successful in component positioning through preop planning and intraop adjustability. …”
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3286
A Digital Mental Health Solution to Improve Social, Emotional, and Learning Skills for Youth: Protocol for an Efficacy and Usability Study
Published 2024-12-01“…Finally, phase 4 will include a year-long pre- and posttest pilot study to rigorously evaluate the usability and effectiveness of Neolth in addressing the mental health concerns of students across the selected schools. ResultsPhase 1 was successfully completed in August 2022, revealing significant deficits in mental health resources within the participating schools. …”
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3287
High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy
Published 2025-03-01“…We employed conventional summary statistics and functional principal component analysis to extract patterns of PA as mediators. …”
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3288
Establishment and Characteristics of the Spermatogonial Stem Cell Line from the Yellow River Carp (<i>Cyprinus carpio haematopterus</i>)
Published 2025-05-01“…Additionally, this study found that YRSSCs possess the ability to differentiate in vitro and functionally colonize in vivo within recipient bodies. …”
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3289
Synthesis of New Pyrazolo[3,4-<i>d</i>]pyrimidine Derivatives: NMR Spectroscopic Characterization, X-Ray, Hirshfeld Surface Analysis, DFT, Molecular Docking, and Antiproliferative...
Published 2024-10-01“…Geometrical parameters were accurately modeled by DFT calculations using the B3LYP hybrid functional combined with a 6–311++G(d,p) basis set. …”
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3290
Creation of Souvenir Products as a Means of Promotion of Historical and Cultural Heritage of the City
Published 2023-12-01“…The methodological basis of the project was theoretical research methods, such as: analysis used to identify and clarify the target audience of the project, and select similar examples, as well as the souvenir market to highlight competitive advantages; synthesis - to identify optimal design solutions and formulate conclusions; comparison - to work with information sources when determining the functionality of the souvenir and its application. …”
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3291
Effect of discontinuing antipsychotic medications on the risk of hospitalization in long-term care: a machine learning-based analysis
Published 2025-08-01“…The use of restraints, age, and functional impairment were relevant variables in all ITE models in influencing the predicted ITE. …”
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3292
Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins
Published 2025-04-01“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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3293
Microwave assisted drug delivery of titanium dioxide/rose Bengal conjugated chitosan nanoparticles for micro-photodynamic skin cancer treatment in vitro and in vivo
Published 2025-05-01“…Despite the fact that novel sensitizers for MWPDT have been successfully synthesized, only a few are being employed effectively. …”
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3294
Implementation HR information system – part of a unified information environment of MPEI
Published 2016-07-01“…The result of the work on the HR information system is stably functioning, supporting all business processes of the subject area and have successfully integrated within other software system. …”
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3295
Determination of malachite green in sediment by ultra performance liquid chromatography-mass spectrometry
Published 2014-05-01“…In order to guarantee the safety of aquaculture, a sensitive and selective analytical method is needed for the determination of MG in aquaculture sediment. …”
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3296
Demographic and Parental Family Determinants of Prostitution Among Iranian Female Sex Workers: A Case-Control Study
Published 2025-07-01“…Again, these factors are directly or indirectly affected by parental family functioning, highlighting the importance of parents’ involvement in the development of their children. …”
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3297
A Simple and Rapid “Turn-On” Fluorescent Probe Based on Binuclear Schiff Base for Zn<sup>2+</sup> and Its Application in Cell Imaging and Test Strips
Published 2024-12-01“…In addition, the paper test and Hela cells were successfully carried out to detect Zn<sup>2+</sup>. Moreover, the sensitivity of bis-Et-SA and bis-Ph-SA is much better than that of those Schiff base ligands containing only one chelating unit [O^N^N^O].…”
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3298
Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation
Published 2022-11-01“…All the patients underwent chest computed tomography (CT). When detecting CT changes, we performed fibrobronchoscopy (FBS) with microbiological examination of bronchoalveolar lavage (BAL).Results. …”
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3299
Biomechanical Changes to the Ankle After Zadek Osteotomy
Published 2024-12-01“…Category: Hindfoot; Sports Introduction/Purpose: Insertional Achilles tendinopathy is a common source of heel pain in active adults and athletes. …”
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3300
Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach
Published 2025-04-01“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
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