Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometritis by Xian Chen, Xian Chen, Mingye Chen, Mingye Chen, Meng Liu, Meng Liu, Lingbin Qi, Zhiqiang Liu, Zhiqiang Liu, Cong Chen, Binfa Liang, Binfa Liang, Xiaobing Yang, Xiaobing Yang, Tao Zhang, Yuye Li, Yuye Li, Ruochun Lian, Ruochun Lian

“…Specifically, DEG analysis showed that genes implicated in endometrial receptivity-related and antimicrobial were upregulated and genes involved in the immune response processes were downregulated in cured CE patients after PRP treatment. Functional enrichment analysis suggested that the effects of changes in leukocyte chemotaxis-related genes played a critical role in the endometrial immune environment.ConclusionsAutologous PRP treatment has been shown as a potentially successful therapy for improving pregnancy outcomes by reconstructing the uterine local immune microenvironment to improve endometrial receptivity in patients with persistent CE.…”
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GWAS and transcriptome analyses unravel ZmGRAS15 regulates drought tolerance and root elongation in maize by Dongmei Wang, Xuyang Liu, Guanhua He, Kailiang Wang, Yongxiang Li, Honghui Guan, Tianyu Wang, Dengfeng Zhang, Chunhui Li, Yu Li

“…By integrating the results of GWAS, DEGs, and WGCNA, four candidate genes (Zm00001d006947, Zm00001d038753, Zm00001d003429 and Zm00001d003553) significantly associated with survival rate were successfully identified. Among them, ZmGRAS15 (Zm00001d003553), a GRAS transcription factor considered as a key hub gene, was selected for further functional validation. …”
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Development of smart samplers and their comparison to dried serum spots for the analysis of growth hormone releasing hormone analogs using LCHRMS/MS by Christina Johannsen, Anna Kha Tu Nguyen, Sasha Shabani, Inger Oulie, Siri Dørum, Yvette Dehnes, Leon Reubsaet, Trine Grønhaug Halvorsen

“…Smart samplers combine sampling and sample preparation in one tool; in this study smart samplers were developed using divinyl sulfone functionalized paper to immobilize antibodies for selective analyte capture. …”
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Patients’ experiences with GLP1-RAs – a systematic review by Christoffer Kraul Ibsen, Marius Brostrøm Kousgaard, Sofie Olsen, Ann-Kathrin Lindahl Christiansen, Catharina Thiel Sandholdt, Rasmus Rørth, Gritt Overbeck

“…The analysis identified five key themes: (1) Patients are willing to accept adverse events, like gastrointestinal disorders, for successful weight loss, (2) Patients experience improved physical functioning, well-being, and active daily living as a result of weight loss, (3) Patients express diverse opinions and skills regarding the medication’s usability, (4) Patients believe that the medication improves their ability to manage sweet cravings, (5) Gender seems to affect patients’ experiences with the medication, with females reporting more benefits than males.Conclusion Despite a huge demand and usage of GLP1-RAs, qualitative research on patients’ experiences is scarce. …”
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Harnessing the microbial interactions from Apocynum venetum phyllosphere for natural product discovery by Wei Huang, Xingzhi Jiao, Lingqi Hua, Qianjin Kang, Lili Zhang, Xiaoxia Luo, Linquan Bai

“…Notably, with the aid of visualization of IMS technology, one of the physiologically functional entities, the bactericidal agent resistomycin, was elucidated from the core interacting pair between the co-culture of the Streptomyces sp. …”
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Green Processing of <i>Ilex guayusa</i>: Antioxidant Concentration and Caffeine Reduction Using Encapsulation by Supercritical Antisolvent Process by Miguel Ángel Meneses, Jhulissa Guzmán, Jhulissa Cabrera, Jorge Magallanes, Eduardo Valarezo, María del Cisne Guamán-Balcázar

“…These results highlight the effectiveness of the SAE co-precipitation process in developing low-caffeine functional ingredients with potential food and pharmaceutical applications.…”
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Complexation with Alginate in Pumpkin Leaf Protein Solutions for the Encapsulation of Folic Acid: The Effect of Extraction Protocols by Predrag Petrović, Bojana Balanč, Jelena Mijalković, Tamara Đukić, Stefan Bošković, Verica Đorđević, Branko Bugarski, Viktor Nedović, Zorica Knežević-Jugović

“…This study aimed to assess pumpkin leaves as a protein source and determine the feasibility of these proteins to form complexes with alginate for the encapsulation of folic acid. …”
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Comparative metabolomic profiling of Lupinus albus and L. angustifolius harvest residues: exploring chemical diversity and valorization potential by Salma Halime, Salma Halime, Jenny Renaut, Stéphanie Zimmer, Hanna Heidt, Cédric Jacquard, Kjell Sergeant

“…Lupin species are a rich source of bioactive compounds with diverse industrial applications, yet their harvest residues remain underutilized. …”
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Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria by Candice L. Wilshire, Carson C. Fuller, Christopher R. Gilbert, John R. Handy, Kimberly E. Costas, Brian E. Louie, Ralph W. Aye, Alexander S. Farivar, Eric Vallières, Jed A. Gorden

“…The electronic medical record (EMR) is a source of clinical information that could identify high-risk populations for LCS, including a diagnosis of COPD; however, an unsubstantiated COPD diagnosis in the EMR may lead to inappropriate LCS referrals. …”
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Investigating Digital Storytelling as a Tool of Improving/ Developing Information Literacy Skills by Maryam Khodabin, Mohammad Zerehsaz, Somaye Sadat Akhshik, Ghasem Azadi Ahmadabadi

“…Digital storytelling emphasizes the group process and people's experience in sharing stories, visual and verbal functions that are necessary for understanding language and thinking from the perspective of cognitive neuroscience. …”
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Canopy Chlorophyll Content Inversion of Mountainous Heterogeneous Grasslands Based on the Synergy of Ground Hyperspectral and Sentinel-2 Data: A New Vegetation Index Approach by Yi Zheng, Yao Wang, Tayir Aziz, Ali Mamtimin, Yang Li, Yan Liu

“…This study confirms that the synergistic use of multi-source data effectively overcomes the limitations of the spectral–spatial resolution of a single data source, providing a novel methodology for the precision monitoring of mountain ecosystems.…”
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The Impact of Mass-dependent Stochasticity at Cosmic Dawn by Viola Gelli, Charlotte Mason, Christopher C. Hayward

“…Comparing to observations, the mass-dependent stochasticity model successfully reproduces the observed LFs up to z ∼ 12. …”
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Integrative bioinformatics and machine learning approach unveils potential biomarkers linking coronary atherosclerosis and fatty acid metabolism-associated gene by Hong Li, Yongyun Xu, Aiting Wang, Chuanxin Zhao, Man Zheng, Chunyan Xiang

“…Conclusions This research has successfully identified seven key FAMGs implicated in AS, offering novel insights into the pathophysiology of the disease. …”
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Current state of the problem of chronic alcoholism, new approaches in its correction (literature review) by E. V. Filippova, K. E. Bukin, A. D. Dyachkova, E. V. Sosnovskaya

“…To select a scheme and successive stages of treatment of chronic alcoholism and withdrawal syndrome, it is necessary to understand the pathogenesis of the disease and the principles of action of the drugs used, in order to determine the points of application of therapy, as well as the stages of pharmacotherapy. …”
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Research on Three-Axis Vibration Characteristics and Vehicle Axle Shape Identification of Cement Pavement Under Heavy Vehicle Loads Based on EMD–Energy Decoupling Method by Pengpeng Li, Linbing Wang, Songli Yang, Zhoujing Ye

“…The findings demonstrate that heavy, slow-moving vehicles generate substantial triaxial vibrations, with the vertical (<i>Z</i>-axis) response exhibiting the greatest amplitude and encompassing higher dominant frequency components compared to the horizontal (X and Y) axes. EMD successfully decomposed the complex signals into discrete intrinsic mode functions (IMFs), identifying high-frequency components (IMF1–IMF3) associated with transient vehicular impacts, mid-frequency components (IMF4–IMF6) presumably linked to structural and vehicle dynamics, and low-frequency components (IMF7–IMF9) representing system trends or ambient noise. …”
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Construction and clinical visualization application of a predictive model for mortality risk in sepsis patients based on an improved machine learning model by Ting Chen, Xuefeng Zhang, Qunfeng Yu, Qin Yang, Lingmin Yuan, Fei Tong

“…This study successfully created a self-evolutionary prediction model using machine learning methods, demonstrating significant clinical application potential and value for broader implementation.…”
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Mobile health apps for skin cancer triage in the general population: a qualitative study on healthcare providers’ perspectives by Tobias E. Sangers, Marlies Wakkee, Folkert Moolenburgh, Tamar Nijsten, Marjolein Lugtenberg

“…Conclusions Although HCPs perceive pivotal risks related to the implementation of mHealth apps, they also foresee important benefits when implemented successfully. In order for HCPs to endorse those apps, emphasis must be placed on integrating accurate mHealth apps with accessible and inclusive design and functionality into clinical practice, factors that currently appear to be largely unmet.…”
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A Seed Endophytic Bacterium <i>Cronobacter dublinensis</i> BC-14 Enhances the Growth and Drought Tolerance of <i>Echinochloa crus-galli</i> by Sheng Cheng, Qingling Wang, Dashan Yang, Quanlong He, Jianxin Deng, Yi Zhou, Lin Zhang, Jianwei Jiang

“…Successful seed germination and plant seedling growth often require association with endophytic bacteria. …”
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Identification and Expression Analysis of Na⁺/K⁺-ATPase and NKA-Interacting Protein in Ark Shells by Man Song, Xiao Liu, Jie Zhang, Wuping Li, Jingfen Pan, Yanglei Jia

“…Phylogenetic analysis revealed a high degree of conservation in the NKA-α and NKA-β subunits across ark shells, suggesting strong selective pressures to preserve their functionality. …”
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Challenges and Management Strategies for Mediterranean Cork Oak Forests: Impacts of Climate Change, Human Activities, and Invasive Species – A Review by Mesfin Boja, Kaouther Mechergui, Wahbi Jaouadi, Youssef Ammari

“…This intrusion alters forest composition, reduces biodiversity, and affects ecosystem functionality. Furthermore, diseases such as Phytophthora cinnamomi are playing a critical role in forest decline by attacking cork oak roots, impairing water and nutrient uptake, and contributing to soil degradation. …”
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