Molecular mechanisms of leukemogenesis by D. A. Domninskiy

“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
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Comparison of the efficacy of one-stage revision surgery guided by precise pathogen diagnosis and conventional two-stage revision for chronic knee periprosthetic joint infection by Zhengwei Xiao, Jinyuan Zeng, Zeyu Zhang, Baijian Wu, Zihao Hong, Yufeng Guo, Chengguo Huang, Zida Huang, Zhaoyang Wu, Wenming Zhang, Xinyu Fang, Wenbo Li

“…Utilizing our optimized pathogen detection protocol, successful pathogen identification was achieved in all cases across both groups. …”
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Incorporating Non-Coding Annotations into Rare Variant Analysis. by Tom G Richardson, Colin Campbell, Nicholas J Timpson, Tom R Gaunt

“…<h4>Background</h4>The success of collapsing methods which investigate the combined effect of rare variants on complex traits has so far been limited. …”
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Distal radial artery ligation for dialysis access-associated ischemic syndrome by ZHANG Li-hong, ZHAN Shen, YANG Tao, WANG Yu-zhu

“…Objective To summarize the experience of treatment for dialysis access-associated ischemic steal syndrome by ligating distal radial artery of radial cephalic fistulas(RCFs).Methods We enrolled hemodialysis patients who used RCFs with complaint of ipsilateral limb ischemia admitted in our department Anatomical prerequisites(side-to-end anastomosis fistula and retrograde flow in the distal radial artery) were checked by ultrasound,the patency of central artery by angiography,and the function of ulnar artery by Allen test Division and ligation of the juxta-anastomosis distal radial artery were performed under regional anesthesia.Clinical presentation,blood flow during hemodialysis,urea clearance index,urea reduction rate,and fistula patency were observed before and after operation.Results This study included 16 patients(8 males and 8 females,accounting for roughly 1.45%of hospitalizations of patients associated with fistula complications at the corresponding time) who underwent DRAL of RCFs with ischemia,of whom the mean age was(66.2 ± 11.2) years,fistula age was(57.75 ± 88.41) months,and the ischemia was detected(39.62 ± 58.31) months after the construction of fistula.According to clinical presentation,71.40%patients were grade Ⅲ,28.60%were grade Ⅱ,and no patients belonged to grade Ⅳ.The technique success rate was 100%and clinical success rate was 93.7%.Blood flow during hemodialysis before and 7 days,6 months and 12 months after operation was(258.63 + 25.44),(246.61 ± 24.24),(260.42 ± 20.83) and(254.87 ± 22.44) ml/min(P>0.05),and Kt/V was(1.65 ± 0.210),(1.59 +0.24),(1.62±0.28) and(1.58 ±0.39)(P>0.05),respectively.The mean follow-up duration was(19.30 ± 13.15) months and the patency rate was 100%.Conclusions DRAL is a simple,safe,and effective technique for dialysis access-associated ischemic syndrome in RCFs.…”
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On path length, beam divergence, and retroreflector array size in open-path FTIR spectroscopy by C. E. N. Power, C. E. N. Power, A. Wiacek, A. Wiacek

“…<p>Open-path Fourier transform infrared (OP-FTIR) spectroscopy is an established technique used to measure boundary layer trace gas concentrations, consisting (in this work) of a spectrometer with an active mid-IR source coupled to a single transmitting and receiving telescope, as well as a cube-corner retroreflector array separated from the spectrometer and telescope by an atmospheric path. …”
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Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs by Sophie-Kristin Heinze, Jürgen Zentek, Kathrin Büttner, Andreas Moritz, Nadine Paßlack

“…An interaction effect between the dietary protein source and protein level could be detected for the phagocytic activity of blood granulocytes as well as for the plasma concentrations of IgA and IgE. …”
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Task-Driven Real-World Super-Resolution of Document Scans by Maciej Zyrek, Tomasz Tarasiewicz, Jakub Sadel, Aleksandra Krzywon, Michal Kawulok

“…We propose to incorporate auxiliary loss functions derived from high-level vision tasks, including text detection using the connectionist text proposal network (CTPN), text recognition via a convolutional recurrent neural network (CRNN), keypoints localization using Key.Net, and hue consistency. …”
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Six-Month Treatment Outcomes of Vital Pulp Therapy in Adults Using Biomaterials: A Prospective Cohort Pilot Study by Melinda Polyák, Eszter Ágnes Szalai, Péter Komora, János Vág

“…Sample size calculations suggested 140 participants would be needed to detect a significant effect of pulp condition. Both materials were effective, though MTA+ showed higher success based on the strict success criteria. …”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“…Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. …”
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Identification of key genes associated with mesocotyl length through a genome-wide association study in rice by Li Xue, Li Xue, Sen Wang, Sen Wang, Qiuyu Zhang, Qiuyu Zhang, Bing Han, Di Cui, Longzhi Han, Jianxin Deng, Xiaoding Ma

“…The results provide new clues to elucidate the molecular mechanism of rice mesocotyl development and lay an important foundation for subsequent gene function verification and molecular breeding. In the future, the functions of these candidate genes will be verified by transgenic and other methods, and molecular markers will be developed for genetic improvement of drought-tolerant rice varieties.…”
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Synthesis and Production of Sweet-Tasting Protein in E. coli and Purification by Amylose Resin by F. Mansouri

“…MBP-brazzein system permits large-scale functional expression and purification of recombinant soluble proteins, providing a basis for the future study of structure and function of brazzein.…”
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Molecular Imaging: A Promising Tool to Monitor Islet Transplantation by Ping Wang, Zdravka Medarova, Anna Moore

“…At present, the lack of an effective approach to islet grafts assessment limits the success of this treatment. The development of molecular imaging techniques has the potential to fulfill the goal of real-time noninvasive monitoring of the functional status and viability of the islet grafts. …”
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Kajian Farmakoinformatika Senyawa Alkaloid Anggur Laut (Caulerpa racemose) Sebagai Inhibitor Collagenase Dalam Mekanisme Antiaging by Dewi Ratih Tirto Sari, M.Eko Pranoto, Siti Zamilatul Azkiyah

“…Sea grapes also well known as functional food source from marine, contains high protein, fibers and secondari metabolites. …”
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Liposomes as Imaging Agents of Inflammation and Oxidative Stress in Bone Implants by Delia Danila, Patricia S. Pardo, R. Devesh Kumar Misra, Aladin M. Boriek

“…Research is ongoing to improve the design and functionality of liposomes. They can potentially monitor bone implants as non-invasive imaging agents, enabling early detection of complications and timely interventions. …”
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Monitoring Dairy Cow Rumination Behavior Based on Upper and Lower Jaw Tracking by Ning Wang, Xincheng Li, Shuqi Shang, Yuliang Yun, Zeyang Liu, Deyang Lyu

“…Finally, the number of rumination chews and the false detection rate were calculated. The system successfully monitored the frequency of the cows’ chewing actions during rumination. …”
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Expression of a humanized viral 2A-mediated lux operon efficiently generates autonomous bioluminescence in human cells. by Tingting Xu, Steven Ripp, Gary S Sayler, Dan M Close

“…While this was disproven when the bacterial luciferase (lux) cassette was demonstrated to function in a human cell, its expression required multiple genetic constructs, was functional in only a single cell type, and generated a significantly reduced signal compared to substrate-requiring systems. …”
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Exploring Image Decolorization: Methods, Implementations, and Performance Assessment by Ivana Žeger, Ivan Šetka, Domagoj Marić, Sonja Grgic

“…The decolorization methods were also examined in the context of object segmentation and edge detection. The results from segmentation and edge detection were aligned with the decolorization results, revealing that certain objective metrics for evaluating decolorization more effectively assessed the properties of the decolorized images, which are crucial for successful object segmentation and edge detection.…”
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PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm by Naeem Shirmohammady, Habib Izadkhah, Ayaz Isazadeh

“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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A survey on the applications of transfer learning to enhance the performance of large language models in healthcare systems by Anmol Rahujo, Daniya Atif, Syed Azeem Inam, Abdullah Ayub Khan, Sajid Ullah

“…This research analyzes different transfer learning methods, including inductive, transductive, and unsupervised techniques, while demonstrating their effectiveness in detecting COVID-19 from chest X-rays and multi-source disease evaluation. …”
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