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2381
Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs
Published 2024-12-01“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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2382
Transformation of the WHO Africa Region Secretariat: an exploratory study of the health policy lessons from health governance strengthening interventions for just and sustainable h...
Published 2025-07-01“…Strengthening partnerships between actors at all health governance levels helps contribute toward resource mobilization required for health system functioning for just and sustained pursuit of universal health coverage.…”
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2383
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2384
OGLE-2011-BLG-0462: An Isolated Stellar-mass Black Hole Confirmed Using New HST Astrometry and Updated Photometry
Published 2025-01-01“…We have reanalyzed the data, including the new HST astrometry, and photometry obtained with 16 different telescopes. The source lies only $0\mathop{.}\limits^{^{\prime\prime} }4$ from a bright neighbor, making it crucial to perform precise subtraction of its point-spread function (PSF) in the astrometric measurements of the source. …”
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2385
Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema
Published 2024-01-01“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
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2386
One more way to address the seasonal water shortage of the largest freshwater lake in China? A nature-based solution through lake bathymetry restoration
Published 2025-06-01“…The simulations evaluated the hydrodynamic impacts of restoration, focusing on its implications for water resource management and ecological functions. New hydrological insights for the region: Results revealed significant impacts of bathymetry restoration, particularly during low-water-level periods. …”
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2387
Valorization of Food Waste: Extracting Bioactive Compounds for Sustainable Health and Environmental Solutions
Published 2025-06-01“…This inefficiency not only increases food insecurity but also results in resource depletion and environmental degradation. Dealing with food waste through sustainable management strategies, such as upcycling food by-products, has proven to be a promising approach to optimize resource use and support the circular economy. …”
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2388
Artificial intelligence in gynecologic and obstetric emergencies
Published 2025-02-01“…Relevant articles were selected and read. Reference lists of the selected articles were also searched. …”
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2389
SIMPLE: Simple Intensity Map Producer for Line Emission
Published 2023-01-01“…Simple can be applied to any spectral line sourced by galaxies. The Simple code is based on lognormal mock catalogs of galaxies including positions and velocities and assigns luminosities following the luminosity function. …”
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2390
Material and Design Analysis of Doors in Traditional Düzce–Konuralp Architecture
Published 2025-02-01“…The analysis encompasses the functions of the doors, their opening directions, horizontal and vertical alignments, dimensions, and material properties, as well as decorative and ornamental characteristics. …”
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2391
Earliest evidence of Neanderthal multifunctional bone tool production from cave lion (Panthera spelaea) remains
Published 2025-07-01“…This study examines the selective use of cave lion bones by Neanderthals to determine whether this behaviour was driven by practical, functional, or symbolic factors, through a detailed zooarchaeological analysis. …”
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2392
De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</...
Published 2024-10-01“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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2393
FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation
Published 2025-05-01“…In this study, FREQ‐NESS is applied to source‐reconstructed magnetoencephalography (MEG) data during resting state and isochronous auditory stimulation. …”
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2394
rangr: An R package for mechanistic, spatially explicit simulation of species range dynamics
Published 2025-03-01“…Several mechanistic, spatially explicit models have been proposed to address this issue, but they do not cover the full range of potential functionalities. We present a new open‐source R package called rangr, which integrates population dynamics and dispersal into a mechanistic virtual species simulator. …”
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2395
A novel method for accelerating surgical wound healing in rabbits by collagen extraction from carp (Cyprinus carpio) fish skin
Published 2025-04-01“…The extracted collagen was characterized by low viscosity, transparency, and a watery consistency; the functional groups of collagens were detected using Fourier Transform Infrared Spectroscopy. …”
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2396
Host selection is not a universal driver of phyllosphere community assembly among ecologically similar native New Zealand plant species
Published 2025-01-01“…Abstract Background A growing body of evidence demonstrates that host-associated microbial communities of plant leaf surfaces (i.e. the phyllosphere) can influence host functional traits. However, it remains unclear whether host selection is a universal driver of phyllosphere community assembly. …”
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2397
The role of Green Building Information Modeling (GBIM) in promoting architectural sustainability
Published 2025-01-01“…A comprehensive review of the literature and previous research is conducted to examine the benefits, challenges, levels of development, data requirements, and functionalities of Green BIM. The study then discusses selected international and regional case studies, in addition to a specific case study in Iraq, to assess the application and effectiveness of Green BIM in achieving sustainability. …”
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Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
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Ecotoxicological evaluation in aquaculture in state park Serra do Mar-SP, Nucleo Itariru
Published 2014-01-01“…We concluded that this fish farm do not represent a source of contamination. Moreover, toxicity tests seem to constitute a tool to evaluate environmental quality in aquaculture.…”
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