Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t... by Mário Henrique Girão Faria, Régia Maria do Socorro Vidal do Patrocínio, Manoel Odorico de Moraes Filho, Silvia Helena Barem Rabenhorst

“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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Rapid parameter estimation for merging massive black hole binaries using continuous normalizing flows by Bo Liang, Minghui Du, He Wang, Yuxiang Xu, Chang Liu, Xiaotong Wei, Peng Xu, Li-e Qiang, Ziren Luo

“…Detecting the coalescences of massive black hole binaries (MBHBs) is one of the primary targets for space-based gravitational wave observatories such as laser interferometer space antenna, Taiji, and Tianqin. …”
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Species-level enumeration of low-concentration lactic acid bacteria in breast milk by Yue Sun, Qiming Li, Mengling Hu, You Wu, Yunchao Wa, Hai Lu, Shilong Jiang, Hui Wang, Qiaosi Wei, Yujun Huang, Ruixia Gu, Chenchen Zhang

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Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…Dairy cows are the most important source of milk production, with billions of microorganisms present in the rumen. …”
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Frontotemporal lobar degeneration changes neuronal beta-frequency dynamics during the mismatch negativity response by Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe

“…Across bvFTD and PSP groups, the beta response to deviant stimuli (relative to standard stimuli) correlated with clinical severity, but not with atrophy of the prefrontal source region. These findings confirm the proposed importance of higher-order cortical regions, and their beta-power generators, in sensory change detection and context-updating during oddball paradigms. …”
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JWST/NIRCam Narrowband Survey of Paβ Emitters in the Spiderweb Protocluster at z = 2.16 by Rhythm Shimakawa, J. M. Pérez-Martínez, Helmut Dannerbauer, Yusei Koyama, Tadayuki Kodama, Pablo G. Pérez-González, Chiara D’Eugenio, Yuheng Zhang, Abdurrahman Naufal, Kazuki Daikuhara

“…Furthermore, we examine the possibility of detecting faint line emitters visible only in the narrowband image but find no promising candidates.…”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Weekly online assessments of mood and anxiety from randomisation to week 52, with psychosocial function, quality of life and healthcare resource utilisation assessments conducted at regular intervals. …”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Secondary outcomes included: unplanned 60- and 90-day hospital re-admissions; quality of transition; health-related quality of life (EuroQol-5 Dimensions, five-level version); and self-reported healthcare resource use. Data sources National Health Service Secondary Use Services data and Hospital Episodes data for work package 2 and routinely recorded National Health Service acute trust hospital data on re-admissions for work packages 5 and 6. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Treatment with insulin is aimed at replicating the function of the pancreas to manage hyperglycaemia and avoid hypoglycaemia. …”
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Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee... by Bahia Moustafa, Neveen A. Soliman, Ihab Shaheen, Ahmed Badr, Fatma M. Atia, Mohamed K. El Hatw, Engy Adel Mogahed, Mona EL-Ghamrawy, Khaled El Khashab, Noha Shaheen, Mohamad G. Shouman, Abeer Selim, Magdy El-Sharkawy, Tarek Abd El Azeem, Mohamad Esmat, Manal Salman, Bedeir Ali-El-Dein, Mona Abdel Rahim, Muhamed A. El-Hadedy, Moatasem Elsayed Ghoneim, Mai S. Korkor, Tarek E. I. Omar, Yasser Amer, Ashraf Abdel Baky, On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee

“…Infections, rejection, recurrence, malignancy, bone problems, hypertension, and surgical complications are the most important challenges that require prevention, early detection, and management. Chronic allograft nephropathy needs different approaches based on its related causes, allograft pathology, graft function, and availability of re-transplantation. …”
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TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury by Ting Zhou, Ziyao Zhang, Yawen Zhan, Meiying Wang, Meiying Wang, Meiying Wang, Mi Wu, Xiufang Weng, Xiufang Weng, Xiufang Weng, Xiufang Weng, Younian Xu, Younian Xu, Younian Xu

“…The ratio, number, phenotype, and function of immune cells and cytokine levels were measured. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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Validation of a 60K SNP chip for caribou (Rangifer tarandus) for use in wildlife forensics, conservation, and management by Trottier-Lavoie Mallorie, Prunier Julien, Poisson William, Carrier Alexandra, Gilbert Isabelle, Mastromonaco Gabriela, Albert Vicky, Cecilia Hernandez, Bourret Vincent, Taillon Joëlle, Droit Arnaud, Côté Steeve D., Robert Claude

“…The SNP chip was shown to be robust, highly sensitive, reliable, and accurate at more than 10-fold below the recommended DNA input. Biological source of DNA had minor impact, even with fecal pellets given sufficient amount of host DNA. …”
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Performance of the HAWC Observatory and TeV Gamma-Ray Measurements of the Crab Nebula with Improved Extensive Air Shower Reconstruction Algorithms by A. Albert, R. Alfaro, C. Alvarez, A. Andrés, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K. S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, C. de León, D. Depaoli, N. Di Lalla, R. Díaz Hernández, B. L. Dingus, M. A. DuVernois, K. Engel, T. Ergin, C. Espinoza, K. L. Fan, K. Fang, N. Fraija, S. Fraija, J. A. García-González, F. Garfias, H. Goksu, M. M. González, J. A. Goodman, S. Groetsch, J. P. Harding, S. Hernández-Cadena, I. Herzog, J. Hinton, D. Huang, F. Hueyotl-Zahuantitla, P. Hüntemeyer, A. Iriarte, S. Kaufmann, A. Lara, J. Lee, H. León Vargas, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, J. Martínez-Castro, J. A. Matthews, P. Miranda-Romagnoli, J. A. Montes, E. Moreno, M. Mostafá, L. Nellen, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, M. Osorio-Archila, Y. Pérez Araujo, E. G. Pérez-Pérez, C. D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, G. Schwefer, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, X. Wang, I. J. Watson, K. Whitaker, E. Willox, H. Wu, S. Yu, S. Yun-Cárcamo, H. Zhou, HAWC Collaboration

“…Thanks to these improvements, HAWC can now detect more sources, including the Galactic center.…”
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Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing by Jiale Zhou, Ding Zhao, Jinze Li, Deqiang Kong, Xiangrui Li, Renquan Zhang, Yuru Liang, Xun Gao, Yuqiang Qian, Di Wang, Jiahui Chen, Liangxue Lai, Yang Han, Zhanjun Li

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Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis by Zilin Hua, Nan Zhou, Zijing Zhou, Zewei Fu, Ruiyun Guo, Herman Yao Akogo, Jiayin Yang, Meixuan Yu, Yujie Jiang, Siyi Lan, Haixia Chang, Jun Ma, Huixian Cui

“…Subgroup analyses indicated that stem cell source, stem cell derivative types and Aβ detection method were not primary drivers of heterogeneity. …”
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Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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