Two rare cases of severe community-acquired bloodstream infections: a clinical case report by Li-Na Meng, Gang Li

“…Detailed medical history inquiries, assessment of underlying immune status, detection of the source of infection, and initial precise identification and treatment of the infectious agents can improve the prognosis of CABSI.Case descriptionIn this paper, two incidences of severe CABSI with insidious onset and rapid progression are described. …”
Get full text

Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Post-treatment evaluation showed normalized complement C3 and C4 levels, stabilized platelet and hemoglobin levels, and gradual normalization of liver function. Renal function improved gradually, and a bone marrow biopsy revealed no fragmented red blood cells. …”
Get full text

P. berghei telomerase subunit TERT is essential for parasite survival. by Agnieszka A Religa, Jai Ramesar, Chris J Janse, Artur Scherf, Andrew P Waters

“…A strategy to delete the gene encoding TERT via double cross-over (DXO) homologous recombination was undertaken to study the telomerase function in P. berghei. Expression of both TERT and the RNA component (TR) in P. berghei blood stages was analysed by Western blotting and Northern analysis. …”
Get full text

C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS‐STING Pathway by Yue Wang, Ting Xu, Wenjun Wang

“…Histopathological examination, level of inflammation, cGAS‐STING pathway, and gut barrier function were detected in mice and cells. Results C9orf72 overexpression in mice attenuated DSS‐induced colitis and intestinal epithelial barrier damage by stimulating ZO‐1 and Occludin expression. …”
Get full text

Efficient collision-avoidance navigation strategy for autonomous surface vehicles in unstructured and constricted marine environments by Wenlong Meng, Rongdian Ku, Yanbo Pu, Xiaoxiao Shi, Ya Gong

“…As the number of samples expands, the random trees gradually enlarge and interlink, mirroring the functionality of classic RRT-connect and ultimately forming a continuous corridor. …”
Get full text

Toward Adaptive Unsupervised and Blind Image Forgery Localization with ViT-VAE and a Gaussian Mixture Model by Haichang Yin, KinTak U, Jing Wang, Wuyue Ma

“…Despite their success, there are still some limitations: (1) A simple Gaussian distribution assumption in the latent space constrains performance due to the diverse distribution of forged images. (2) Gaussian Mixture Models (GMMs) introduce non-convex log-sum-exp functions in the Kullback–Leibler (KL) divergence term, leading to gradient instability and convergence issues during training. (3) Estimating GMM mixing coefficients typically involves either the expectation-maximization (EM) algorithm before VAE training or a multilayer perceptron (MLP), both of which increase computational complexity. …”
Get full text

Multimodal prediction of trait emotional intelligence-Through affective changes measured using non-contact based physiological measures. by Vrinda Prajapati, Rajlakshmi Guha, Aurobinda Routray

“…This adversely affects the individual's psychological functioning. A higher trait emotional intelligence (EI) is not only associated with psychological wellbeing, educational attainment, and job-related success, but also with willingness to seek professional and non-professional help for personal-emotional problems, depression and suicidal ideation. …”
Get full text

Commercial chip-based tunneling magnetoresistance sensor for green-synthesized magnetic nanoparticles assay by Pinaka Elda Swastika, Harlina Ardiyanti, Zurnansyah, Deska Lismawenning Puspitarum, Nurul Imani Istiqomah, Nur Aji Wibowo, Edi Suharyadi

“…The sensor system successfully detected MNPs at different stray field intensities. …”
Get full text

Gait-based Parkinson’s disease diagnosis and severity classification using force sensors and machine learning by Navita, Pooja Mittal, Yogesh Kumar Sharma, Anjani Kumar Rai, Sarita Simaiya, Umesh Kumar Lilhore, Vimal Kumar

“…The results indicate that the proposed dual-stage model is exceptionally successful in the early detection and severity assessment of Parkinson’s disease and demonstrates better efficacy than alternative models.…”
Get full text

Liver Injury Associated with Antituberculosis Medications by Syifa Mustika, Lia Susanti

“…Tailored therapeutic approaches, comprehensive liver function monitoring, and early identification of DILI are vital for minimizing hepatotoxicity while ensuring successful tuberculosis management. …”
Get full text

Identification method of roof rock interface based on response characteristics of drilling parameters by LI Dianshang, LIU Cancan, WANG Chuanbing, REN Bo, REN Shuai, KANG Zhipeng

Get full text

Uji Kualitas Website Admin Travel Booking Menggunakan Halstead’s Metric dan Equivalence Partitioning by Fauziah Nur Syifa, Trisana Nurul Anzali Nabil, Derrel Hendi Arifin, Rangga Sidik

“…Blackbox testing ensures the software meets the set requirements and specifications and detects functional and performance errors. Whitebox testing is done to check the software's logical path by examining the software's logical structure and detecting errors, such as logical errors and script understanding errors. …”
Get full text

Specificity of Methylation Assays in Cancer Research: A Guideline for Designing Primers and Probes by Zeinab Barekati, Ramin Radpour, Corina Kohler, Xiao Yan Zhong

“…This highlights the critical need for specific primer and probe design to avoid false-positive detection of methylation profiling. The guideline and online web tools that are introduced in this paper might help to perform a successful experiment and to develop specific diagnosis biomarkers by designing right primer pair and probe prior to experimental step.…”
Get full text

Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake by Leah R. N. Samuels, Houston C. Chandler, Michelle Hoffman, John A. Kronenberger, Michele Elmore, Robert Aldredge, Benjamin S. Stegenga, James E. Bogan Jr., Mark A. Davis, Stephanie Hertz, Michael K. Schwartz, Taylor Wilcox

Get full text

Study of Complex Impedance Dispersion Model for Two-Phase Laminar Flow by CHENG Linfeng, KE Shizhen, SHI Hongwei, ZHANG Yuhang, LUO Hu, TAO Jie

Get full text

Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
Get full text

Multiagent Systems as an Approach to Building Fuzzy voter Communities using fuzzy languages by Milambu Belangany, Pierre Kasengadia Motumbe, Eugène Mbuyi Mukendi

“…Results demonstrate that fuzzy communities can be successfully constructed, where the membership function quantifies the degree of belonging of voters to specific communities. …”
Get full text

Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA. by Emel Akdoğan, Mehmet Tardu, Görkem Garipler, Gülkız Baytek, İ Halil Kavakli, Cory D Dunn

“…Since mitochondrial function and biogenesis are controlled by the nutrient environment of the cell, it is possible that perturbation of conserved, nutrient-sensing pathways may successfully treat mitochondrial disease. …”
Get full text

A comparative study of adrenalin and fluocinolon induced oxidative stress in male wistar rats by Erika KIS

“…In this study, we used electron paramagnetic resonance spectroscopy for the direct detection of free radical content in the organs of stressed Wistar rats. …”
Get full text

Modern Hardware and Software Solutions for Whole-Genome Sequencing, Prospects of Their Implementation in the Practice of Nuclear, Chemical and Biological Protection Troops of the A... by A. A. Petrov, A. V. Kazantsev, E. A. Kovalchuk, M. Yu. Pavlyukov, A. V. Sapkulov, D. A. Kutaev, S. V. Borisevich

“…Despite its great potential, NGS has not yet been widely adopted in clinical microbiology laboratories, partly due to the lack of standardized workflows.Conclusions. For the successful use of NGS by units of the RCB protection troops of the Armed Forces of the Russian Federation, it is necessary to solve the main problem, which is the development of domestic hardware, appropriate bioinformatics tools and databases certified in accordance with the established procedure for functioning offiine without connecting to the Internet.…”
Get full text