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641
Development of an Electrochemical Paper-Based Device Modified with Functionalized Biochar for the Screening of Paracetamol in Substandard Medicines
Published 2024-11-01“…This study introduces a cost-effective electrochemical paper-based device (ePAD) modified with functionalized bamboo-derived biochar (BCF) for the detection of paracetamol in substandard medicines. …”
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642
Anti-RNA virus crRNA targets efficient screening platform based on bioinformatics and CRISPR detection
Published 2025-09-01“…This method significantly reduces the screening time for antiviral targets compared with traditional cell screening. We successfully designed and screened effective crRNA targeting SARS-CoV-2 conserved N gene regions and demonstrated its inhibition function in HEK 293T cells. …”
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643
Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection
Published 2025-07-01“…Current immunodetection methods using antibody-DNA conjugates enable multiplexed target detection through orthogonal DNA barcodes, but existing conjugation approaches are labor-intensive and often compromise antibody function. …”
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644
Large field-of-view plasmonic scattering imaging and sensing of nanoparticles with isotropic point-spread-function
Published 2025-06-01“…Compared with SPRM, Chip-PSM retains high detection sensitivity and in situ label-free analysis capability, while offering a larger field-of-view, an isotropic point-spread-function and higher spatial resolution. …”
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645
Detection and prediction of real-world severe asthma phenotypes by application of machine learning to electronic health records
Published 2025-08-01“…Results: Three principal components (PCs) emerged, reflecting lung function (PC1), blood inflammatory markers (PC2), and systemic corticosteroid receipt (PC3). …”
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646
High-throughput functional analysis provides novel insight into type VII secretion in Staphylococcus aureus
Published 2024-08-01“…Successful colonization by the opportunistic pathogen Staphylococcus aureus depends on its ability to interact with other microorganisms. …”
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650
Computational Temporal Ghost Imaging Using Intensity-Only Detection Over a Single Optical Fiber
Published 2018-01-01“…We propose a method of computational temporal ghost imaging over a single optical fiber using simple optical intensity detection instead of coherent detection. The transfer function of a temporal ghost imaging system over a single optical fiber is derived, which is a function of the total fiber dispersion and the power density spectrum of the light source. …”
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651
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652
The Reliable Detection of Homocysteine Using a Biosensor Based on Recombinant Cystathionine β-Synthase and Nanoporous Gold
Published 2025-03-01“…Given the essential roles of homocysteine (Hcy) and the interference of cysteine in effectively monitoring human health, this study proposed a synergistic effect strategy that combines the unique structural and functional properties of nanoporous gold (NPG) with the selective recognition capability of a recombinant cystathionine β-synthase (CBS) for the sensitive and specific detection of Hcy. …”
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653
Deep learning-based image classification of sea turtles using object detection and instance segmentation models.
Published 2024-01-01“…Despite their successful application in this domain, detecting objects in images with complex backgrounds, including underwater environments, remains a significant challenge. …”
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654
A contamination-free electrolyte-gated organic transistors platform for high-accuracy tumor biomarker detection
Published 2025-06-01“…A novel biosensor platform for high-accuracy tumor biomarker detection exploiting contamination free microfluidics for increasing the signal-to-noise ratio has been successfully developed and tested. …”
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655
Picomolar Detection of Tau Protein Using 1D Photonic Crystal Biochips for Alzheimer's Disease Diagnosis
Published 2025-05-01“…This innovative method enables label‐free analysis of the bio‐conjugation process on biochips used for resolved fluorescence‐based Tau detection. This work successfully demonstrates Tau protein detection in both matrixes, achieving an outstanding limit of detection of 2.4 pM in cerebrospinal fluid. …”
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656
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657
Vulnerability detection using BERT based LLM model with transparency obligation practice towards trustworthy AI
Published 2024-12-01“…The result shows higher accuracy of 91.8 % for the vulnerability detection and model explainability outcome is highly influenced by “vulnerable”, “function”, ''mysql_tmpdir_list'', “strmov” tokens using both SHAP and LIME framework. …”
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658
Design Molecular Imprinting Polymer Coupled with Spectrophotometric Detection for the Determination of Tramadol Hydrochloride in Pure and Pharmaceutical Formulations
Published 2025-08-01“…Acrylamide was used as the functional monomer, trimethylolpropane Trimethacrylate as the cross-linker, and tramadol hydrochloride as the template molecule to make Molecularly Imprinted Polymer (MIP). …”
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659
A Defect Detection Method for Flexible Thermal Control Film Manufacturing Process Driven by Digital Twin
Published 2025-02-01“…Then, a vacuum coating defect detection algorithm is designed, integrating adaptive convolution + spatial pyramid module, enhancing multi-scale features through FPN/ PAN, optimizing anchor boxes and lightweight design, achieving a detection speed of 140 FPS at 91. 5% accuracy. …”
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660
Pequi-Derived Carbon Dots as a Fluorescence Quenching Sensor for Sensitive Detection of Fe3+ Ions
Published 2025-04-01“…This study presents the pequi (Caryocar coriaceum) as a new biomass source for carbon dots synthesis. The pequi almond, usually discarded, was used as the biomass precursor in one-step hydrothermal green synthesis of carbon dots. …”
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