Positioning, navigation, and timing on the Moon and Mars with galactic cosmic rays by G. Leone, H.K.M. Tanaka, M. Holma, S. Krishnan, A.R. Duffy, T. Enqvist, P. Kuusiniemi, J. Joutsenvaara, G. Cerretto, E. Cantoni, M. Sellone, J. Marteau, D. Lo Presti, J.G. Szűcs, D. Varga

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Experimental evidence quantifying effects of nocturnal light conditions on predation levels by riverine predators on larval prey by Joseph J. Riedy, Edward A. Baker, Kim T. Scribner

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Identification of an IRF8 gene in common carp (Cyprinus carpio. L) and its regulatory role in immune responses by Yaoyao Zhu, Guiwen Yang

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Retinal vein occlusion risk prediction without fundus examination using a no-code machine learning tool for tabular data: a nationwide cross-sectional study from South Korea by Na Hyeon Yu, Daeun Shin, Ik Hee Ryu, Tae Keun Yoo, Kyungmin Koh

“…An easy-to-use oversampling function was employed to address class imbalance, enhancing the usability of the workflow. …”
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Oligosaccharide production using β-galactosidase from Lactobacillus bulgaricus and Kluyveromyces lactis in sweetened reconstituted nonfat dry milk by Giselle K.P. Guron, Arland T. Hotchkiss, Jr., Brittany H. Bodnar, Andrew Harron, John A. Renye, Jr., Michael J. McAnulty

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Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care by Xuerong Lv, Ke Yan, Xiang Han, Feiyang Wang, Yuzhuo Ma, Shougang Zhang, Xiaoqian Wang

“…Objectives Microbial contamination of various accessory parts of the dental chair units (DCUs) is an essential source of cross infection, while the accessories of the crucial suction function are usually overlooked. …”
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Polystyrene micro and nanoplastics: A comparative study of the cytotoxic effects exerted on Mytilus galloprovincialis gills by R. Romano, L. Rosati, G. Napolitano, F. Ferrigno, T. Chianese, C.M. Motta, P. Simoniello

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Rapid and sensitive determination of bongkrekic acid with molecularly imprinted polymer-coated wooden-tip electrospray ionization mass spectrometry by Chunfei Zhong, Xinyan Li, Fan Zhang, Ning Liu, Jiewei Deng, Yunyun Yang, Tiangang Luan

“…The practical application of the method was confirmed through the successful analysis of real-world samples, including tap water, wastewater from a food processing factory, and the aqueous extracts of food samples, with BA detected at 0.296 µg/L in Tremella. …”
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circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p by Jiayuan Su, Jinrong Zhou, Yachan Feng, Haojie Zhang, Xinyu Zhang, Xiaorong Zhao, Yong Li, Xueling Guo

“…Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers, accounting for around 80% of total lung cancer cases worldwide. Exploring the function and mechanism of circRNAs could provide insights into the diagnosis and treatment for NSCLC. …”
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Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment by Andrew McGarry, MD, Oliver Roesler, PhD, Jackson Liscombe, PhD, Michael Neumann, PhD, Hardik Kothare, PhD, Abhishek Hosamath, MBM, Lakshmi Arbatti, MS, Anusha Badathala, MD, Stephen Ruhmel, BS, MPH, Bryan J. Hansen, PhD, Madeline Quall, BA, Sandrine Istas, MBio, Arthur Wallace, MD, PhD, David Suendermann-Oeft, PhD, Vikram Ramanarayanan, PhD, Ira Shoulson, MD

“…A complementary approach using digital biomarkers to surpass exam-based limitations for detecting physical change coupled with a direct report from participants on what their sources of suffering are could be a useful advance in reporting beneficial effects of interventions, particularly if changes track together. …”
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Prediction of Genes Related to Positive Selection Using Whole-Genome Resequencing in Three Commercial Pig Breeds by HyoYoung Kim, Kelsey Caetano-Anolles, Minseok Seo, Young-jun Kwon, Seoae Cho, Kangseok Seo, Heebal Kim

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Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR by Hans Tobias Gustafsson, Lucas Ferguson, Carolina Galan, Tianxiong Yu, Heather Upton, Ebru Kaymak, Zhiping Weng, Kathleen Collins, Oliver J Rando

“…Taken together, our data confirm the superior performance of OTTR to commercial protocols in analysis of tRNA fragments, and force a reappraisal of potential epigenetic functions of the sperm small RNA payload.…”
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Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…In MCI, early serotonergic dysregulation involving SERT occurs before detectable atrophy.…”
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Exploration of the interaction between antimicrobial peptides and gamma radiation for biosensor development. by Fabiane Modenese Garbim, Marcela Rabelo De Lima, Giulianna Santos Pereira, João Nilton Conceição Bandeira, Álvaro José Mendes-Boareto, Fernando Manuel Araújo-Moreira, N.F.G. Serrano

“…These findings indicate that, although AMPs demonstrate changes in activity as a function of dose and could be explored for biosensing, their functional stability is limited at higher radiation doses. …”
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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development by Tingting Zhou, Ningbo Huangfu, Li Wang, Junyu Luo, Jinjie Cui, Xiangzhen Zhu, Sumei Wan, Xueke Gao

“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging by Hong-Fei Li, Bao Dong, Yuan-Yuan Peng, Hao-Yue Luo, Xiao-Lan Ou, Zheng-Lin Ren, Yoonseong Park, Jin-Jun Wang, Hong-Bo Jiang

“…Further analysis of the mutant flies revealed that sets of odorant receptor (OR) genes were differentially expressed. Functional characterization of the differentially expressed ORs suggested that sulfakinin directly suppresses the expression of ORs that respond to opposite-sex hormones while enhancing the expression of ORs that detect food volatiles. …”
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Genotype × environment interaction analysis and climatic factors impacts on grain yield in rainfed durum wheat trials in Iran by Reza Mohammadi, Moslem Abdipour, Mahnaz Rahmati, Mohammad Armion, Nastaran Mehri, Asghar Mehraban

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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart by Niko Järveläinen, Paavo J. Halonen, Jussi Nurro, Antti Kuivanen, Juho Pajula, Miikka Tarkia, Maria Grönman, Antti Saraste, Johanna Laakkonen, Pyry Toivanen, Tiina Nieminen, Tuomas T. Rissanen, Juhani Knuuti, Seppo Ylä-Herttuala

“…AdVammin treatment also increased ejection fraction at stress in the ischemic heart, as detected using left ventricular cine angiography. In addition, we demonstrated successful in vivo imaging of enhanced angiogenesis using [68Ga]NODAGA-RGD peptide. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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