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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice
Published 2020-01-01“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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1722
Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes
Published 2025-02-01“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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1723
Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3
Published 2025-12-01“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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1724
Protective role of extracellular vesicles against oxidative DNA damage
Published 2025-03-01“…Abstract Background Oxidative stress, a source of genotoxic damage, is often the underlying mechanism in many functional cell disorders. …”
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1725
Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap
Published 2025-07-01“…An algorithm was designed to detect these cases based on the geometry of the street segments. …”
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1726
Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria
Published 2025-03-01“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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1727
IDENTIFICATION OF ELECTROMAGNETIC ULTRA LOW FREQUENCY (ULF) SIGNAL ANOMALIES AS PRECURSORS OF A MAGNITUDE 5 EARTHQUAKE IN THE SULAWESI REGION
Published 2024-05-01“…The anomaly source azimuth direction was also determined.…”
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1728
Regional and strain-level prevalence of nitrogen-fixing Bradyrhizobium with potential N2O reduction in South Korea
Published 2025-06-01“…Abstract Agricultural practices are the largest anthropogenic source of nitrous oxide (N2O), a potent greenhouse gas contributing to global climate change. …”
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1729
Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution.
Published 2009-05-01“…These events are thought to be a source of genomic instability and human diseases, but it is unclear whether they have contributed significantly to genome evolution. …”
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1730
Devicology: Expanding fieldwork possibilities for architectural observations in inhabited interiors
Published 2022-04-01“…These visually chaotic yet surprisingly functional structures are the only tool of the current dwellers to negotiate with the restricting standard apartment plans that were originally designed for a very different sector of the Japanese population. …”
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1731
The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters
Published 2025-01-01“…We study the differences in the demographics of BH–BH mergers and their implications for LIGO–Virgo–Kagra detections as a function of ${f}_{{\rm{b}},15}^{{\prime} }$ .…”
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1732
Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis
Published 2024-12-01“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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1733
Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains
Published 2025-06-01“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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1734
Evaluation of Cloud Masking Methods using Sentinel-2 Satellite Images on Google Earth Engine: A Case Study in Vietnam
Published 2024-09-01“…These include the Fmask (Function of mask) method, the Fmask CDI (Cloud Displacement Index) method, and the Fmask CSP (Cloud Score Plus) method. …”
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1735
Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability
Published 2024-10-01“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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1736
Joint Survey Processing. III. Compact Oddballs in the COSMOS Field—Little Red Dots and Transients
Published 2025-01-01“…We draw the upper limit of the AGN luminosity function Φ = 1.1 × 10 ^−7 Mpc ^3 mag ^−1 for M _UV = −21 at redshift of 6. …”
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1737
Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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1738
Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation
Published 2025-07-01“…Given that the broad impact of improved psychoeducation for carers of adults with eating disorders has been widespread, and many of the materials are disseminated, we suggest that signposting the existing resources for carers could be part of the standard package. …”
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1739
Current status of transcriptome sequencing technology in ruminants
Published 2025-06-01“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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1740
User Communities — Drivers for Open Innovation
Published 2014-03-01“…Users best judge what will lead to commercial success, and they have long been recognized as a valuable source of knowledge to harvest for future innovation. …”
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