Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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Application of Optimization Algorithms in Voter Service Module Allocation by Edgar Jardón, Marcelo Romero, José-Raymundo Marcial-Romero

“…Allocation models are essential tools for optimally distributing client requests across multiple services under defined restrictions and objective functions. This study evaluates several heuristics to address an allocation problem involving young individuals reaching voting age. …”
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ABOUT OF THE ASSIGNING APPEARANCES TO LOCOMOTIVE CREWS by Sergey P. Vakulenko, Aleksey V. Kolin, Airat M. Nasybullin, Liliya R. Aysina

“…This optimization could improve the planning of labor resource availability with a longer-term perspective. …”
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Tracking teachers’ experience of adopting my English step to infuse differentiated instruction by Ilza Mayuni, Yinghui Chen, Ni Made Ratminingsih, Tara Mustikaning Palupi, Nurhasanah Halim

“…This digital educational resource can be modified and adhered to its contextual connection. …”
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Towards liquid biopsy on chip for Triple Negative Breast Cancer: preliminary results on monitoring circulating miRNA-21 using portable diagnostics by Alessandra Glovi, Panagiota M. Kalligosfyri, Antonella Miglione, Sima Singh, Gabriella Iula, Antonio Giordano, Michelino De Laurentiis, Stefano Cinti

“…In this work, miRNA-21 was selectively detected using a complementary DNA probe modified with methylene blue, as a redox mediator, immobilized onto an AuNPs-functionalized, paper-based screen-printed electrode. …”
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Evaluation of Cloud Masking Methods using Sentinel-2 Satellite Images on Google Earth Engine: A Case Study in Vietnam by Le Minh Hang, Bui Xuan Hung, Nguyen Thi Thu Nga, Mai Phuong Pham, Nguyen Quoc Khanh

“…These include the Fmask (Function of mask) method, the Fmask CDI (Cloud Displacement Index) method, and the Fmask CSP (Cloud Score Plus) method. …”
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Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability by Huangzhe Dai, Chengqian Zhang, Hao Hu, Zhezai Hu, Haonan Sun, Kan Liu, Tiefeng Li, Jianzhong Fu, Peng Zhao, Huayong Yang

“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray by Yuncai Shen, Tingfeng Yi, Vinit Dhiman, Lisheng Mao, Liang Dong

“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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Advancing Enzyme-Based Detoxification Prediction with ToxZyme: An Ensemble Machine Learning Approach by Kashif Iqbal Sahibzada, Shumaila Shahid, Mohsina Akhter, Muhammad Faisal, Reham A. Abd El Rahman, Muhammad Imran, Yangyong Lv, Dongqing Wei, Yuansen Hu

“…The aaccurate prediction of enzymes with environment detoxification functions is crucial, not only to achieve a better understanding of bioremediation strategies, but also to alleviate environmental pollution. …”
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A Framework for Qualitative Analysis of Switching Techniques of Inductive Pulse Power Supply by Ayaz Ahmed, Zulkurnain Abdul-Malek, Hasmat Malik, Majed A. Alotaibi

“…This research examines the functionality, results, and constraints of the pulse transformer, Meatgrinder, and XRAM-based IPPS circuit topologies using different switching techniques, such as stretch Meatgrinder, ICCOS, SECT, CPFU, ACC, BCSC, and TWPT. …”
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Current status of transcriptome sequencing technology in ruminants by Cui JiaYu, Song Lili, Wang Dawei, Liu ZhiLin, Zhang Xin, Jia Zelin, Zhang Yuhang, Xiong Huisheng, Wang Xueli

“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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Discovery of Genomic Targets and Therapeutic Candidates for Liver Cancer Using Single-Cell RNA Sequencing and Molecular Docking by Biplab Biswas, Masahiro Sugimoto, Md. Aminul Hoque

“…This study aims to uncover key genomic features, analyze their functional roles, and propose potential therapeutic drugs identified through molecular docking, utilizing single-cell RNA sequencing (scRNA-seq) data from liver cancer studies. …”
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User Communities — Drivers for Open Innovation by Gunnar Prause, Thomas Thurner

“…Users best judge what will lead to commercial success, and they have long been recognized as a valuable source of knowledge to harvest for future innovation. …”
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REVIEW OF: GOLUBKOVA O.N. FUNDAMENTALS OF SCIENTIFIC RESEARCH IN THE PROFESSIONAL FIELD: TEXTBOOK by A.A. Bilyalova, A.N. Utekhina

“…The textbook serves as a valuable resource for preparing for lectures and practical sessions, as well as for independent study. …”
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Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

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Plasmonic optical fiber biosensors for ultra-low detection of respiratory syncytial virus via point-of-care tests by Federica Passeggio, Luigi Zeni, Massimiliano Galdiero, Francesco Arcadio, Carla Zannella, Anna De Filippis, Chiara Marzano, Ines Tavoletta, Fabiana Napolitano, Rosalba Pitruzzella, Giuseppe Portella, Nunzio Cennamo

“…This protein was selected because it is the most conserved surface protein between the two RSV subtypes, RSV A and RSV B. …”
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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Effects of Rumen-Protected Methionine on Meat Quality, Fatty Acid Composition, Volatile Flavor Compounds and Transcriptomics of <i>Longissimus lumborum</i> of Yak (<i>Bos grunniens... by Xia Wu, Zizhen Zuo, Jiajia Li, Jianhui Fu, Jincheng Zhong, Hui Wang, Haitao Shi, Yanling Huang, Haibo Wang

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Assessing key soft skills in organizational contexts: development and validation of the multiple soft skills assessment tool by Daiana Colledani, Daiana Colledani, Egidio Robusto, Pasquale Anselmi

“…The present study aimed to develop and validate the Multiple Soft Skills Assessment Tool (MSSAT), a short self-report instrument that evaluates interpersonal skills (initiative-resourcefulness, assertiveness, conflict management), interpersonal communication skills, decision-making style (adaptive and maladaptive), and moral integrity.MethodsThe scale development process involved selecting and adapting relevant items from existing scales and employing a cross-validation approach with a large sample of workers from diverse organizational settings and job positions (N = 639). …”
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A quantum inspired machine learning approach for multimodal Parkinson’s disease screening by Diya Vatsavai, Anya Iyer, Ashwin A. Nair

“…As disease progression impairs speech, memory, and motor functions over time, early diagnosis is crucial for preserving patients’ quality of life. …”
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