Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…Bioinformatics analysis was conducted to explore the function of GJB4 in PC cells. Changes in ferroptosis in PC cells following GJB4 downregulation were detected by immunofluorescence staining, transmission electron microscopy, and western blotting.ResultsGJB4 expression was found to be upregulated in PC tissues and positively correlated with patient survival. …”
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Unravelling the Impact of an Additional Sex Chromosome in an Adult Female by Sigin George, Vikas Dagar, Barun Kumar Chakrabarty, N. Nagaraja

“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
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Advancing Predictive Healthcare: A Systematic Review of Transformer Models in Electronic Health Records by Azza Mohamed, Reem AlAleeli, Khaled Shaalan

“…Notably, case studies demonstrated a 30% boost in entity recognition accuracy in clinical notes and a 90% detection rate for malignancies in medical imaging. …”
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Biochemical, nutritional, and nutraceutical properties of cactus pear accessions by Yazgan Tunç, Mehmet Yaman, Kadir Uğurtan Yılmaz, Ali Khadivi, Daya Shankar Mishra

“…These findings contribute valuable insights for the conservation and utilization of wild cactus pear genetic resources, supporting the development of functional food products and sustainable cultivation strategies in Mediterranean climates.…”
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Semi-Automated Dataset Generation for Residential Buildings Using Graph-Based Topological Modelling by Angelo Massafra, Dania H. Al-Harasis, Lorenzo Stefanini, Wassim Jabi

“…The resulting dataset facilitates the analysis of floor spatial configurations and the extraction of geometric attributes, laying the foundation for future analyses that will integrate machine learning techniques for functional detection and typological clustering.…”
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Analysis of genomic selection characteristics of local cattle breeds in Gansu by Bao Cai, Yandong Kang, Lin Xiong, Jie Pei, Qianyun Ge, Xiaoyun Wu, Manyu Gan, Xian Guo

“…It provides a theoretical basis for conserving breed resources, identifying functional genes, and developing breeding strategies.…”
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Comparing the Transcriptomes of Two Different Tissues in Helicoverpa assulta (Guenée) by Hailing Zhang, Kuiyin Li, Yubo Zhang

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Advanced Suspension Techniques in Interferometric Gravitational Wave Detectors: An Overview by Vishnu G. Nair

“…This isolation is crucial for enabling the detectors to function efficiently at low frequencies, which directly impacts their capacity to detect distant events from the universe’s past. …”
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Growth and Form Trait Variation Analysis Among Different Clones of Michelia chapensis by Zhixi DENG, Baishuan LYU, Rong HUANG, Limin ZHOU, Runhui WANG, Li CHEN, Zhijun LAI, Jiaqi CHEN, Jie ZHU, Ruping WEI, Huiquan ZHENG

“…Significant (P < 0.05) to highly significant (P < 0.01) phenotypic and genetic correlations were detected among the traits (except between tree height and crown-to-diameter ratio). …”
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A quantum inspired machine learning approach for multimodal Parkinson’s disease screening by Diya Vatsavai, Anya Iyer, Ashwin A. Nair

“…As disease progression impairs speech, memory, and motor functions over time, early diagnosis is crucial for preserving patients’ quality of life. …”
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Feasibility of estimating the percentage of desert pavement using Tasseled Cap Transformation indices extracted from Landsat 8 images by farzaneh Fotouhi Firoozabad, Atefeh jebali

“…Tasseled cap transformation functions were used to present the characteristics of soil brightness, greenness, and moisture in six distinct maps. …”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…Fatty acids, among other substrates, are utilized by immune cells as an energy source. Therefore, L-carnitine, which is authorized as a feed additive in cattle, may influence the metabolism of peripheral blood mononuclear cells (PBMC) during an immune challenge. …”
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Design and Development of an EMG Upper Limb Controlled Prosthesis: A Preliminary Approach by Ricardo Rodrigues, Daniel Miranda, Vitor Carvalho, Demétrio Matos

“…Preliminary results demonstrate reliable detection of muscle contractions (threshold = 7 ADC units, ~34 mV) and motor actuation with a response time of ~150 ms, offering a cost-effective alternative to commercial systems. …”
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PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. by Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton

“…Therefore, computational methods which, given a set of 3D coordinates, can automatically identify and describe channels in transmembrane proteins are key tools to provide insights into how they function.Herein we present PoreWalker, a fully automated method, which detects and fully characterises channels in transmembrane proteins from their 3D structures. …”
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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins by Ruolan Yi, Jiaoyang Zheng, Zhichao Xu, Jiayan Wu, Fangfang Liu, Jinxin Zheng, Duoyun Li, Shiqing Han, Zhijian Yu

“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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Soil lipid analysis by chromatography: A critical review of the current state in sample preparation by Gladys Arteaga-Clemente, María Araceli García-González, Mónica González-González

“…Despite its minor component in soils, the lipid fraction is of particular importance. Its functional diversity offers an inherent diagnostic value regarding soil organic matter, microbial biodiversity and the pedological processes to which the soil is subjected. …”
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A methodology for quantitatively managing the bug fixing process using Mahalanobis Taguchi system by Boby John, R. S. Kadadevarmath

“…The controlling of bug fixing process during the system testing phase of software development life cycle is very important for fixing all the detected bugs within the scheduled time. The presence of open bugs often delays the release of the software or result in releasing the software with compromised functionalities. …”
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Accuracy of Vegetation Height and Terrain Elevation Derived from Terrestrial Ecosystem Carbon Inventory Satellite in Forested Areas by Zhao Chen, Sijie He, Anmin Fu

“…Forest ecosystems serve as pivotal components of the global carbon cycle, with canopy height representing a critical biophysical parameter for quantifying ecosystem functionality, thereby holding substantial implications for forest resource management and carbon sequestration assessments. …”
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Proteomic analysis of plasma unravels dynamic pathways and potential biomarkers indicating disease stages following Mtb infection by Zonglei Zhou, Jie Tian, Yuying He, Haiyan Xiong, Weibing Wang

“…ABSTRACT Tuberculosis (TB) stages depend greatly on the interaction between Mycobacterium tuberculosis (Mtb) and the host response. As a non-negligible source of active tuberculosis (ATB), individuals with latent Mtb infection (LTBI) are insidious and hard to be detected due to limited biomarkers. …”
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Open Radio Access Networks “O-RAN” SystemsThroughput improvement) by Russul Qasim, Ismail S. Baqer

“…A new conceptual design has been created for network configuration, deployment, and functions. This design uses interchangeable components from various vendors and can be optimized for performance through a centralized inference layer and data-driven control. …”
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