Glyceraldehyde-3-phosphate dehydrogenase acts as a mitochondrial trans-S-nitrosylase in the heart. by Mark J Kohr, Elizabeth Murphy, Charles Steenbergen

“…Mitochondrial proteins have been shown to be common targets of S-nitrosylation (SNO), but the existence of a mitochondrial source of nitric oxide remains controversial. SNO is a nitric oxide-dependent thiol modification that can regulate protein function. …”
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Risks as an object of internal control: identification and assessment by М.М., I.I.

“…The main purpose of internal control is to ensure timely detection and analysis of business risk, reliability of relevant information, integrity of assets, compliance with regulations, internal policies and procedures, implementation of plans and efficient use of resources. …”
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

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Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins by Nan Li, Hongna Liu, Zhongxing Song, Rui Zhou, Zhishu Tang, Zhishu Tang, Hongbo Xu, Xinbo Shi, Yanru Liu, Jian Ni

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Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria by Hadjira Guenane, Boulanouar Bakchiche, Ramazan Erenler, Ilyas Yildiz, Omar M. Khalaf, Amal M. Saad, Mosad A. Ghareeb

“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
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Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…In comparison to the RNAi-mediated gene silencing of <i>dicer-2</i>, <i>argonaute-2b</i>, and <i>piwi5</i>, our Cas9/sgRNA approach showed an enhanced ability to detect antiviral effects. <b>Conclusions</b>: We propose that this cell line offers a new tool for studying gene function in <i>Cx. quinquefasciatus</i> mosquitoes that avoids the use of RNAi. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Two-Stage Detectors with Multiple Energy Detectors and Adaptive Double Threshold in Cognitive Radio Networks by Ashish Bagwari, Geetam Singh Tomar

“…Cognitive radio (CR) is a regulated technique for opportunistic access of idle resources. In CR, spectrum sensing is one of the key functionalities. …”
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Epidemic preparedness and response capacity against infectious disease outbreaks in 186 countries, 2018–2022 by Paul Eze, Judith Chidumebi Idemili, Friday Onwubiko Nwoko, Nigel James, Lucky Osaheni Lawani

“…From the 2022 submissions, 116 (62%) countries reported functional (Level 4 or 5) prevention capacity, 162 (87%) had functional detection capacity, 118 (63%) had functional response capacity, 121 (65%) had functional enabling resources and coordination capacity, and 133 (72%) had functional operational readiness against public health events. …”
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Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…Specifically, we obtain the Rossby number Ro as a function of planetary depth and orbital period, after showing that tidal synchronization is likely valid for all HJs. …”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Unveiling the complex double-edged sword role of exosomes in nasopharyngeal carcinoma by Xueyan Huang, Yuedi Tang

“…Exosomes are small membrane vesicles at the nanoscale that transport physiologically active compounds from their source cell and have a crucial function in signal transmission and intercellular message exchange. …”
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Face Recognition Door Security System and Contactless Bell by Rini Irnayanti, Elfizon Elfizon

“…Face recognition uses OpenCV based on an open source library to recognize faces in realtime using the Python programming language.  …”
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Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
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Gene Network Biological Validity Based on Gene-Gene Interaction Relevance by Francisco Gómez-Vela, Norberto Díaz-Díaz

“…Finally, the ability of GeneNetVal to detect biological functionality of the network is shown.…”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs by Sophie-Kristin Heinze, Jürgen Zentek, Kathrin Büttner, Andreas Moritz, Nadine Paßlack

“…An interaction effect between the dietary protein source and protein level could be detected for the phagocytic activity of blood granulocytes as well as for the plasma concentrations of IgA and IgE. …”
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Dietary compositions and their seasonal shifts in Japanese resident birds, estimated from the analysis of volunteer monitoring data. by Tetsuro Yoshikawa, Yutaka Osada

“…Determining the composition of a bird's diet and its seasonal shifts are fundamental for understanding the ecology and ecological functions of a species. Various methods have been used to estimate the dietary compositions of birds, which have their own advantages and disadvantages. …”
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Molecular mechanisms of leukemogenesis by D. A. Domninskiy

“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
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Whole blood RNA-seq analysis reveals the immunomodulatory effects of a supplemental multi-strain direct-fed microbial in the diet of newly weaned beef steers1 by Adekunle Ajiboye, Samanthia Johnson, Modoluwamu Idowu, Yarahy Leal, Taylor Sidney, Godstime Taiwo, Ibukun M. Ogunade, Christopher Ashwell

“…Forty newly weaned Angus crossbred steers (12-h postweaning; 217 ± 4.6 kg of body weight [BW]; 202 ± 4 d of age) from three different sources were stratified by BW and randomly assigned to one of the two treatments: 1) basal diet with no additive (CON; n = 20), and 2) the basal diet supplemented with 9 g/steer/d of a multi-strain microbial additive (PRO; n = 20). …”
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