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Dissecting the genetic basis of response to salmonid alphavirus in Atlantic salmon
Published 2025-07-01“…Additionally, another QTL on Ssa07 was detected, linked to infection-specific response. Transcriptomics analysis of the genes overlapping the Ssa03 QTL region revealed significant expression differences among three tandemly duplicated gig1-like genes, whereas allele-specific expression analysis detected several SNPs with putative functional impact on the particular genes. …”
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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WHSC1/NSD2 regulates immune infiltration in prostate cancer
Published 2021-02-01Get full text
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Integrated microbiome and metabolome approaches reveal the resistant mechanisms of leaf blight resistant plum cultivar
Published 2025-05-01“…By harnessing these natural microbial and metabolic resources, it may be possible to develop sustainable, eco-friendly strategies for managing leaf blight, ultimately reducing the dependency on chemical pesticides. …”
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Metagenome Analysis Identified Novel Microbial Diversity of Sandy Soils Surrounded by Natural Lakes and Artificial Water Points in King Salman Bin Abdulaziz Royal Natural Reserve,...
Published 2024-12-01“…Results: In this study, sandy soil samples from the surroundings of natural and artificial water resources of two distinct natures were used. Based on 16S rRNA sequencing, a total of 24,563 OTUs were detected. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT
Published 2025-05-01“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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Comparative nutrient and sensory analysis of eight different commercial Chlorella powders
Published 2025-06-01Get full text
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A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors
Published 2025-06-01“…We also used the Tumor Immune Estimation Resource 2.0 (TIMER 2.0) database to investigate the association between ZNF514 expression and immune checkpoint genes and immune infiltration. …”
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LH Gene Cloning, Sequence Feature Analysis and Prokaryotic Expression in Conger myriaster
Published 2025-06-01“…Conger myriaster is an economic valuable fishery resources in the seas surrounding China, Korea, and Japan. …”
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Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad...
Published 2012-09-01“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress
Published 2022-09-01“…Off-label, clinical practice frequently outpaces solid evidence as rigorous clinical trials require substantial time and resources. Murine models present an opportunity for high throughput dose finding studies to focus subsequent clinical trials in humans. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Published 2024-12-01“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization
Published 2022-12-01“…In addition, functional analysis of the cnf1-positive clinical strain EC131GY ST131-H30Rx/C2 and a cnf1-deleted isogenic strain showed no detectable impact of the CNF1 gene on bacterial fitness and inflammation during the acute phase of bladder monoinfection. …”
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