Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis by Ricardo Félix Morais, José Maria Sousa, Cemal Koba, Leon Andres, Tiago Jesus, Inês Baldeiras, Tiago Gil Oliveira, Isabel Santana

“…In MCI, early serotonergic dysregulation involving SERT occurs before detectable atrophy.…”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study by Liu Xiaoyan, Bao Zhongying, Duan Shuhong, Sun Jing, Zhang Yijie, Zhang Jie, Liu Jingxin

“…Emergency department data functioned as an independent external validation set to test the model’s generalizability.ResultsThe study included 1,007 patients, with 778 in the training set and 229 in the validation set. …”
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Socioeconomic Inequity in Access to Medical and Long-Term Care Among Older People by Shohei Okamoto, Atsuhiro Yamada, Erika Kobayashi, Jersey Liang

“…Conclusion Improving the understanding of available resources and strengthening the functions of health centres and communities are required to detect the needs of citizens and facilitate their access to necessary care.…”
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Complexation with Alginate in Pumpkin Leaf Protein Solutions for the Encapsulation of Folic Acid: The Effect of Extraction Protocols by Predrag Petrović, Bojana Balanč, Jelena Mijalković, Tamara Đukić, Stefan Bošković, Verica Đorđević, Branko Bugarski, Viktor Nedović, Zorica Knežević-Jugović

“…This study aimed to assess pumpkin leaves as a protein source and determine the feasibility of these proteins to form complexes with alginate for the encapsulation of folic acid. …”
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Heritage in real life: between appreciation and contempt: why are modern Egyptians continuously losing their heritage? by Medhat Wassef

“…To achieve that goal, I have been researching literary and academic resources in the fields of Heritage studies and national identity for the roots of these misconceptions, and trying to connect them with the everyday life of society. …”
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Antioxidant potential of tree bark extracts: Insight from the multi-level output of the Antioxidant Power 1 assay. by Johanna Rehrl, Thomas Sepperer, Sissy Häsler Gunnarsdottir, Thomas Schnabel, Gertie Janneke Oostingh, Anja Schuster

“…Tree bark is a complex protective tissue that serves both physiological and defensive functions and is particularly rich in phenolic compounds bearing antioxidant, antimicrobial, anti-inflammatory and wound healing properties. …”
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Morpho-Molecular and Genomic Characterization of <i>Penicillium mexicanum</i> Isolates Retrieved from a Forsaken Gold Mine by João Trovão, Fabiana Soares, Diana Sofia Paiva, António Portugal

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Bioactives and Other Nutritional Components in the Jaggery Production Process by Nisha Pujari, Nirali Dedhia, Sanjay Mahajani, Narendra Shah, Amit Arora

“…Jaggery, a non-centrifugal sugar (NCS), is a naturally produced sweetener and a good source of minerals, essential vitamins and bioactives. …”
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Solar background radiation temperature calibration of a pure rotational Raman lidar by V. Jayaweera, R. J. Sica, G. Martucci, A. Haefele, A. Haefele

“…These measurements enable climatology studies and trend analyses to be performed. To detect long-term trends it is critical that the calibration of the system and the monitoring of its associated uncertainties are as reliable and continuous as possible. …”
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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…This study provided a valuable resource for understanding the molecular basis of JD, potentially contributing to the genetic improvement of JD resistance in dairy cattle.…”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Methods Tumor Immune Estimation Resource (TIMER), The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases were utilized for bioinformatics analysis. …”
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Statistics on the Industry Structure of the Russian Economy and its Optimization Model by O. V. Morozov, M. A. Vasiliev

“…According to the statistics for 2018, reflecting the resource capacity (employment, fixed assets, number of organizations) and the results of activities (value added, investment activity), econometric calculations of the relative (in comparison with the entire economy) sizes of the Russian economy sectors were made. …”
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VULVAR AND VAGINAL GRAFT VERSUS HOST DISEASE IN A PATIENT WITH CHRONIC PHASE CHRONIC MYELOID LEUKEMIA AFTER ALLOGENEIC STEM CELL TRANSPLANTATION by Esra Pirinççi, M. Orhan Ayyıldız, Abdullah Karakuş, Reyhan Gündüz

“…In our patient, this condition was detected approximately 5 years after allogeneic transplantation. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Multi-Locus GWAS Mapping and Candidate Gene Analysis of Anticancer Peptide Lunasin in Soybean (<i>Glycine max</i> L. Merr.) by Rikki Locklear, Jennifer Kusumah, Layla Rashad, Felecia Lugaro, Sonia Viera, Nathan Kipyego, Faith Kipkosgei, Daisy Jerop, Shirley Jacquet, My Abdelmajid Kassem, Jiazheng Yuan, Elvira de Mejia, Rouf Mian

“…Our study is an important effort to understand the genetic basis and functional genes for lunasin production in soybean seeds.…”
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Estimation of bacterio‐, picophyto‐ and nanophytoplankton abundance in the Middle Caspian Sea by flow cytometry by V. S. Mukhanov, T. V. Rauen, S. V. Vostokov, A. S. Vostokova, E. N. Lobachev

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Effect of -O- on Water Molecule Adsorption and Adsorption Mechanism of Lignite and Coke by Xue Bai, Yue Yin Song, Ying Yue Teng, Wen Lu Zhang, Yin Min Song, Yun Fei Wang

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Characterization of the diversity, genomic features, host bacteria, and distribution of crAss-like phages in the pig gut microbiome by Yaxiang Wang, Chao Wei, Zhe Chen, Mengqing Zhou, Lusheng Huang, Congying Chen

“…Approximately 64.73% of crAss-like phage genes lacked functional annotations, highlighting a gap in understanding their functional potential. …”
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Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…Phase 2 – realist synthesis: Empirical and grey literature, together with online discussion boards, social media sources and blogs were used to create initial programme theories regarding service architecture. …”
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