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Genome-Wide Association Study of Immune Indices in Yaks
Published 2025-07-01“…The yak is a vital livestock resource on the Qinghai–Tibet Plateau, renowned for its strong disease resistance and high-quality meat. …”
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Microbial community characteristics and environmental response of water bodies in different environmental areas underground coal mine
Published 2025-02-01“…These functions maintained the ecological balance of underground water bodies in coal mines and played an important role in regulating and restoring ecosystems.…”
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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin
Published 2025-10-01Get full text
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1447
Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin
Published 2025-12-01“…Background Rectal adenocarcinoma (READ) involves the dysregulated expression of alpha 2,8-Sialyltransferase1 (ST8Sia1) although its role during READ’s progression is unclear.Methods The mRNA level of ST8Sia1 was analyzed based on The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Tumor Immune Estimation Resource (TIMER) 2.0. Furthermore, the prognostic and significance of ST8Sia1 in READ was assessed through Kaplan-Meier curve, univariate, multivariate Cox regression, and receiver operating characteristic (ROC) methods. …”
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1448
Clinical profile and molecular genetic analysis of alport syndrome in children: a single center experience
Published 2024-12-01“…Genetic testing emerged as a critical resource for diagnosing AS. Furthermore, early diagnosis is crucial for implementing an appropriate management plan and assessing the prognosis.…”
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Glucosylceramides containing very long-acyl-chain fatty acid are critical for cotton fiber elongation by influencing brassinosteroid synthesis and signaling
Published 2025-08-01“…Cotton fiber is one of the longest plant cells and sphingolipids are closely associated with the development of cotton fiber cells. However, their function in cotton fiber cell development and its action mechanism is unclear. …”
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1451
Comparing soil microbial diversity in smallholder plantain backyard gardens and main farms in Western and Central Africa
Published 2025-08-01“…Beneficial genera such as Bacillus, Streptomyces, Bradyrhizobium, and Paenibacillus were also detected. Functional predictions based on COG and KEGG databases indicated notable differences in microbial functional potential between the two settings. …”
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1452
Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice
Published 2025-07-01Get full text
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1453
Assembly and comparative analysis of the complete mitochondrial of Spodiopogon sagittifolius, an endemic and protective species from Yunnan, China
Published 2025-03-01“…Abstract Background Spodiopogon sagittifolius, a C4 plant closely related to cultivated crops, is an edible resource and a Class II nationally protected species in China. …”
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1454
Integrated genomic and transcriptomic analysis of polydactyly in chickens
Published 2025-05-01Get full text
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1455
Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development
Published 2025-08-01“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…One of the most important indicators that can be used to attract bank resources and assess how to use resources (optimal allocation of resources) and incomes, is the productivity index in the discussion of management quality. …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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Molecular mechanisms of leukemogenesis
Published 2022-11-01“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
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Spatial Appraisal of Seasonal Water Yield of the Sokoto-Rima Basin
Published 2021-08-01“…Understanding the dynamics of water yield as relates to water balance is vital for the functioning of ecosystems as well as model-based computation of their respective ecosystem services. …”
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