MSC-Derived Extracellular Vesicles Activate Mitophagy to Alleviate Renal Ischemia/Reperfusion Injury via the miR-223-3p/NLRP3 Axis by Zejia Sun, Zihao Gao, Jiyue Wu, Xiang Zheng, Shizhao Jing, Wei Wang

“…MSC-derived extracellular vehicles (EVs) exhibit a protective functional role in renal ischemia/reperfusion injury (RIRI). …”
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Optimization in High-pressure Microfluidics Preparation of Black Pepper Essential Oil Nanoemulsion by Response Surface Methodology and Its Component Analysis by Yaxin TAN, Song WU, Hanyue YANG, Xiaoya YUAN, Yonggui PAN

“…The particle size of BPEO nanoemulsion prepared under these conditions was 126.64 nm and the polymer dispersity index (PDI) was 0.238. Most of the functional groups of Tween 80 and BPEO exist in the BPEO nanoemulsion, and the wavenumber changes of the characteristic absorption peaks were slightly small, which proved that BPEO was successfully wrapped in the droplet. …”
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Multimorbidity and associated outcomes among older adult inpatients with neurological disorders by Aroldo BACELLAR, Telma ASSIS, Bruno Bacellar PEDREIRA, Luan CÔRTES, Silas SANTANA, Osvaldo José Moreira do NASCIMENTO

“…Methods: We enrolled patients aged ≥60 years successively admitted to a tertiary medical center with NDs between January 1, 2009, and December 31, 2010. …”
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Novel resistance to Cydia pomonella granulovirus (CpGV) in codling moth shows autosomal and dominant inheritance and confers cross-resistance to different CpGV genome groups. by Annette J Sauer, Eva Fritsch, Karin Undorf-Spahn, Petr Nguyen, Frantisek Marec, David G Heckel, Johannes A Jehle

“…Commercial Cydia pomonella granulovirus (CpGV) products have been successfully applied to control codling moth (CM) in organic and integrated fruit production for more than 30 years. …”
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Reduced representation sequencing reveals genetic diversity and adaptive genetic divergence in Calamus rhabdocladus by Rui Gu, Ruijing Xu, Songpo Wei, Pär K. Ingvarsson, Shaohui Fan, Guanglu Liu

“…The Latent Factor Mixed Model (LFMM) identified 955 loci significantly associated with environmental adaptation and successfully aligned 469 genes from related species, which were enriched in functional categories involving cell structure, carbohydrate metabolism, and protein degradation. …”
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Genome-wide identification and analysis of SmRR gene family in eggplant (Solanum melongena L.) and their response to abiotic stress and auxin by Wenjing Li, Hui Li, Yanyu Lin, Yutong Li, Xiaofang Xie, Xuefang Zheng, Weiren Wu, Yuanchang Zhou, Yan Zheng

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Early life microbiome disbalance impacts neuroendocrine outcomes in pre-pubertal mice in a sexually dimorphic manner by Bistra B. Nankova, Bistra B. Nankova, Furong Hu, Edmund F. LaGamma, Edmund F. LaGamma, Edmund F. LaGamma

“…Maternal antibiotics during nursing caused: (1) microbial dysbiosis in the offspring as evident by markedly enlarged ceca, no detectable by-products of bacterial fermentation (sp. …”
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Pretest probability of coronary artery disease as a factor for optimizing invasive diagnostics in routine clinical practice by M. A. Simonyan, T. Yu. Kalyuta, E. N. Genkal, O. M. Posnenkova, V. I. Gridnev

“…In 2017-2019, the number of detected CAD cases and proportion of men increased. …”
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Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia by Jinli Yao, Yanqing Qin, Dongping Tu, Yumei Huang, Liuguan Liang, Wenhui Cai, Mingli Huang, Xiaoqi Zhu, Xinling Lao

“…This study provided references for gene functional expression analysis and laid a foundation for decoding the senkirkine biosynthesis pathway. …”
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Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective prop... by Wenyun Xiong, Lixia Guo, Yiting Zhang, Shurui Li, Zihuan Wu, Shengbao Cai

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Integrating parental genomes to reduce reference bias and identify intramuscular fat genes in Qinchuan Black pigs by Guangquan Lv, Peiyu Yang, Ao Guo, Minghao Cao, Dong Li, Zhe Liu, Mingyu Wang, Jingchun Sun, Rongrong Ding, Taiyong Yu

“…Selection signal analysis based on the integrated parental genomic strategy successfully identified more differentiated windows and positively selected genes. …”
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Effects of Clozapine, Haloperidol, and the NMDA Antagonist Ketamine on Novel Object Recognition in <i>Gnathonemus petersii</i>: A New Possible Model for Schizophrenia Research by Petra Horká, Josefina Mavrogeni, Veronika Langová, Pavel Horký, Jan Hubený, Ivana Chrtková, Karel Valeš, Martin Kuchař, Jiří Horáček

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Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology by Mattia Santoni, Giovanni Piccinini, Giovanni Piccinini, Giovanni Liguori, Maria Roberta Randi, Massimo Baroncini, Liliana Milani, Francesca Danesi

“…The optimized model successfully detected concentration-dependent oxidative stress responses to TiO₂ exposure, revealing cellular dysfunction preceding membrane damage.DiscussionThis improved co-culture system provides a better physiological platform for nanotoxicology studies. …”
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Foamy Melamine Resin–Silica Aerogel Composite-Derived Thermal Insulation Coating by Dongfang Wang, Yabin Ma, Yingjie Ma, Baolei Liu, Dewen Sun, Qianping Ran

“…The results of foamy structure analyses via scanning electron microscopy, micro-CT, and N₂ adsorption–desorption isotherms validate the successful generation of a micro-scale porous structure with the enhancement of the aerogel nano-scale solid particles at the wall as a stabilizer. …”
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Experience of extended transtriceps approach in osteosynthesis of complex fractures of the distal metaepiphysis of the humerus by A. Yu. Sergyeev, A. M. Fain, A. Yu. Vasa, S. F. Gnetetsky, V. B. Bondarev

“…Evaluation of treatment results confirms that osteosynthesis using this access allows to reduce the time and trauma of the operation, to avoid complications associated with osteotomy of the olecranon, and to carry out successful postoperative rehabilitation, achieving good functional results.…”
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A Review: The Beauty of Serendipity Between Integrated Circuit Security and Artificial Intelligence by Chen Dong, Decheng Qiu, Bolun Li, Yang Yang, Chenxi Lyu, Dong Cheng, Hao Zhang, Zhenyi Chen

“…Integrated circuits are the core of a cyber-physical system, where tens of billions of components are integrated into a tiny silicon chip to conduct complex functions. To maximize utilities, the design and manufacturing life cycle of integrated circuits rely on numerous untrustworthy third parties, forming a global supply chain model. …”
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Indocyanine green fluorescence to ensure perfusion in middle segment-preserving pancreatectomy: a case report by Tomohiro Iguchi, Norifumi Iseda, Kosuke Hirose, Mizuki Ninomiya, Takuya Honboh, Takashi Maeda, Fumi Sawada, Yu-ichi Tachibana, Tetsuro Akashi, Naotaka Sekiguchi, Noriaki Sadanaga, Hiroshi Matsuura

“…Abstract Background Middle segment-preserving pancreatectomy (MSPP) is an alternative to total pancreatectomy that allows for the preservation of the endocrine and exocrine functions of the pancreas. However, maintaining perfusion to the pancreatic remnant is of critical importance. …”
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CLSTM-MT (a Combination of 2-Conv CNN and BiLSTM Under the Mean Teacher Collaborative Learning Framework): Encryption Traffic Classification Based on CLSTM (a Combination of 2-Conv... by Xiaozong Qiu, Guohua Yan, Lihua Yin

“…The identification and classification of network traffic are crucial for maintaining network security, optimizing network management, and ensuring reliable service quality. These functions help prevent malicious activities, such as network attacks and illegal intrusions, while supporting the efficient allocation of network resources and enhancing user experience. …”
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Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
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Microplastics as an Emerging Potential Threat: Toxicity, Life Cycle Assessment, and Management by Sameh S. Ali, Mohammed Hussein M. Alsharbaty, Rania Al-Tohamy, Maha A. Khalil, Michael Schagerl, Majid Al-Zahrani, Jianzhong Sun

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