Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy by Ping Li, Alice Butler, Yu Zhou, Karl L. Magleby, Christina A. Gurnett, Lawrence Salkoff

“…The Kv3.2 subfamily of voltage activated potassium channels encoded by the KCNC2 gene is abundantly expressed in neurons that fire trains of fast action potentials that are a major source of cortical inhibition. Gain-of-function (GOF) de novo pathogenic variants in KCNC1 and KCNC2, encoding Kv3.1 and Kv3.2 respectively, cause several types of epilepsy including developmental and epileptic encephalopathy (DEE). …”
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Microbial diversification is maintained in an experimentally evolved synthetic community by Zahraa Al-Tameemi, Alejandra Rodríguez-Verdugo

“…We further observed loss-of-function mutations in flagellar genes that were fixed in monocultures but not in co-cultures. …”
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Galar - a large multi-label video capsule endoscopy dataset by Maxime Le Floch, Fabian Wolf, Lucian McIntyre, Christoph Weinert, Albrecht Palm, Konrad Volk, Paul Herzog, Sophie Helene Kirk, Jonas L. Steinhäuser, Catrein Stopp, Mark Enrik Geissler, Moritz Herzog, Stefan Sulk, Jakob Nikolas Kather, Alexander Meining, Alexander Hann, Steffen Palm, Jochen Hampe, Nora Herzog, Franz Brinkmann

“…Galar consists of 80 videos, culminating in 3,513,539 annotated frames covering functional, anatomical, and pathological aspects and introducing a selection of 29 distinct labels. …”
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Overview of Effects of Motor Learning Strategies in Neurologic and Geriatric Populations: A Systematic Mapping Review by Li-Juan Jie, PhD, Melanie Kleynen, PhD, Guus Rothuizen, MSc, Elmar Kal, PhD, Andreas Rothgangel, PhD, Susy Braun, PhD

“…Data Sources: PubMed, CINAHL, and Embase were searched. …”
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Autophagy in aquatic animals: mechanisms, implications, and future directions by Md. Abu Kawsar, Md. Abu Kawsar, Md. Abu Kawsar, Md. Abu Kawsar, Diponkor Adikari, Yang Zhang, Yang Zhang

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Livestock Production Challenges and Improved Forage Production Efforts in the Damot Gale District of Wolaita Zone, Ethiopia by Shimelis Mengistu, Ajebu Nurfeta, Adugna Tolera, Melkamu Bezabih, Abera Adie, Endalkachew Wolde-meskel, Mesfin Zenebe

“…These forages are produced for the purpose of two or more functions (feed, cash, and preventing erosion) that vary (p ≤ 0.01) among intervention status. …”
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Biochar Quality During Slow Pyrolysis from Oil Palm Empty Fruit Bunches and Its Application as Soil Ameliorant by Amsar Maulana, Mimien Harianti, Salma Athiyya, Teguh Budi Prasetyo, Moli Monikasari, Irwan Darfis, Dewi Rezki, Herviyanti Herviyanti

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ORGANIZING THE WORK OF THE DONOR BREAST MILK BANK AT THE LVIV PERINATAL CENTER IS AN EXPERIENCE THAT MOTIVATES FURTHER DEVELOPMENT by М. Малачинська, М. Кісельова, О. Шлемкевич, Н. Вереснюк, Г. Коваленко

“… Human milk is considered the primary source of nutrition for breastfed infants and is justifiably regarded as the “gold standard.” …”
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IndoHerb: Indonesia medicinal plants recognition using transfer learning and deep learning by Muhammad Salman Ikrar Musyaffa, Novanto Yudistira, Muhammad Arif Rahman, Ahmad Hoirul Basori, Andi Besse Firdausiah Mansur, Jati Batoro

“…The rich diversity of herbal plants in Indonesia holds immense potential as alternative resources for traditional healing and ethnobotanical practices. …”
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Comparison of Methods for Isolation and Characterization of Total and Astrocyte‐Enriched Extracellular Vesicles From Human Serum and Plasma by Leandra K. Figueroa‐Hall, Kaiping Burrows, Ahlam M. Alarbi, Bethany N. Hannafon, Cole Hladik, Chibing Tan, Rajagopal Ramesh, Jennifer L. Stewart, Victoria B. Risbrough, Martin P. Paulus, T. Kent Teague

“…This study provides a comprehensive resource for researchers in selecting EV isolation methods tailored to small biobanked clinical samples, with the goal of advancing biomarker discovery in Neuroscience.…”
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Agroclimatic and agroecotoxicological justification of zonal chemical protection systems against harmful organisms for field crops under conditions of climate change in Ukraine by O. Borzykh, L. Bublyk, V. Chaika, L. Gavrylyuk, I. Kruk, O. Shevchuk, T. Neverovska, O. Bakhmut

“…This led to a disruption in the functioning of agrocenoses, a decrease in tolerance to the pesticide load. …”
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Developing a Comprehensive Physical Education Curriculum in Secondary Schools: Identifying and Exploring the Key Components of Content by Yurij Vaskov

“…A systematic review of relevant literature was conducted using publications from the Vernadskyi National Library and sources in the Google search system. Keywords were used for the search in accordance with the topic of the study, and 26 sources were selected for analysis. …”
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Pollution Characteristics and Water Quality Status of Water Storage Pond in Xianyang City of Shaanxi Province by Zhou Fuyu, Gao Zhaoliang, Zhang Shuai, Li Yonghong, Sun Guanfang, Lou Yongcai, Ai Jianwei, Liu Wenbo

“…Treatment methods suitable for the rural environment should be selected according to the characteristics of water pollution.…”
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Where there’s smoke there is fire: Türkiye and the international illegal wildlife trade by Özgün Emre Can

“…Trafficked wild animals and wildlife products are moving between source and demand regions in the Americas, Africa, Asia and Europe. …”
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Baseline levels of microplastics in agricultural soils obscure the effects of additional microplastics from recycled fertilizers by Collin J. Weber, Dominika Kundel, Andreas Fliessbach, Else K. Bünemann, Moritz Bigalke

“…Whilst it was observed from the fluxes that digestate can be a substantial source of microplastics to soils, the comparatively short time of application and the high background at our investigated sites leads to a obscured effect where digestate inputs serve a limited function.…”
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Quality and content evaluation of thyroid eye disease treatment information on TikTok and Bilibili by Haisheng Wang, Huahong Zhang, Jiamin Cao, Feng Zhang, Wei Xiong

“…Abstract Thyroid eye disease (TED) is an autoimmune condition that commonly impacts patients’ visual function, appearance, and psychological well-being. …”
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Developing a Delphi Consensus on the Domains and Conduct of Brief Geriatric Assessments in Singapore by Jonathan Gao, Penny Lun, Lay Khoon Lau, Woan Shin Tan, Edward Tan, Wee Shiong Lim, Reshma Aziz Merchant, Laura Tay, Yew Yoong Ding

“…Participants agreed on targeting selected older adults for BGA to identify geriatric syndromes; physical, psychological, function, mobility/balance, and social status as domains to assess for BGA; and healthcare professionals administering BGA. …”
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Structural knowledge-driven meta-learning for task offloading in vehicular networks with integrated communications, sensing and computing by Ruijin Sun, Yao Wen, Nan Cheng, Wei Wang, Rong Chai, Yilong Hui

“…By optimizing the computation mode and network resources, in this paper, we investigate an I-CSC-based task offloading problem to reduce the cost caused by resource consumption while guaranteeing the latency of each task. …”
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Insect seedling herbivory is influenced by multiple factors, but the plant apparency theory is more supported than other hypotheses – A case study in a subtropical forest by Baozhu Yuan, Bo Wang

“…In total, 24 potential variables that represented abiotic resource availability, characters of individual seedlings, conspecific and heterospecific species, and the whole seedling community were selected to test several commonly discussed alternative herbivory hypotheses. …”
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Bronchial asthma in children of Ukraine: medical and environmental parallels of morbidity and prevalence by O. P. Volosovets, Y. K. Bolbot, S. P. Kryvopustov, O. V. Mozyrska, M. V. Kryvopustova, M. P. Prokhorova, A. V. Kupkina

“…Over the past 25 years in Ukraine there has been 69.3% increase in prevalence and 22.9% increase in incidence of bronchial asthma among children. Predominance of detecting this pathology was in the group of children from large industrial and agro-industrial regions of the country with significant volumes of atmospheric pollutants from stationary sources of pollution.…”
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