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1681
Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases
Published 2025-08-01“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
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1682
Comprehensive Phenotypic Characterization and Genomic Analysis Unveil the Probiotic Potential of <i>Bacillus velezensis</i> K12
Published 2025-03-01“…The complete genome sequencing of <i>B. velezensis</i> K12 revealed a genomic length of 3,973,105 base pairs containing 4123 coding genes, among which 3973 genes were functionally annotated. The genomic analysis identified genes associated with acid and bile tolerance, adhesion, antioxidants, and secondary metabolite production, whereas no functional genes related to enterotoxins or transferable antibiotic resistance were detected, thereby confirming the probiotic properties of <i>B. velezensis</i> K12. …”
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1683
Identification and Analysis of Phenolic Compounds in <i>Vaccinium uliginosum</i> L. and Its Lipid-Lowering Activity In Vitro
Published 2024-10-01“…(VU), rich in polyphenols, is an important wild berry resource primarily distributed in extremely cold regions. …”
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1684
Robustness of viral load over CD4 cell count in measuring the quality of life of people with HIV at second line regimen in Amhara region
Published 2025-04-01“…Monitoring the quality of life of people under treatment helps to optimize the resource allocated for the program. Therefore, the main objective of the current study was to assess the quality of life comparing viral load and CD4 cell count and factors affecting the variable of interest among HIV-positive people under the second-line regimens. …”
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1685
Transcriptome analysis reveals common and distinct mechanisms for sheepgrass (Leymus chinensis) responses to defoliation compared to mechanical wounding.
Published 2014-01-01“…Additionally, the distinct DEGs represent a valuable resource for novel gene discovery that may improve plant resistance to defoliation from various processes.…”
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1686
A methodology for quantitatively managing the bug fixing process using Mahalanobis Taguchi system
Published 2015-12-01“…The controlling of bug fixing process during the system testing phase of software development life cycle is very important for fixing all the detected bugs within the scheduled time. The presence of open bugs often delays the release of the software or result in releasing the software with compromised functionalities. …”
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1687
New strategies and advancements in the synthesis of metal organic frameworks for PAHs removal
Published 2025-06-01“…Globally, the increased urbanization and industrialization lead to a lack of resources and the discharge of harmful/toxic chemicals like polyaromatic hydrocarbons (PAHs) into the environment. …”
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1688
Oxidative Stress Markers and C-Reactive Protein Are Related to Severity of Heart Failure in Patients with Dilated Cardiomyopathy
Published 2014-01-01“…The aim of study was to determine relationships between functional capacity (NYHA class), left ventricle ejection fraction (LVEF), hemodynamic parameters, and biomarkers of redox state and inflammation in patients with dilated cardiomyopathy (DCM). …”
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1689
Enhancing Medium-Chain Fatty Acid Delivery Through Bigel Technology
Published 2024-11-01“…This study presents the development and characterization of medium-chain fatty acid (MCFA)-loaded bigels, using coconut oil as the MCFA source. The bigels exhibited high oil binding capacity, ranging from 87% to 98%, effectively retaining MCFAs within the matrix, with lauric acid (C12) being the main component detected within the bigels at 178.32 ± 0.10 mg/g. …”
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1690
A Jurisprudential and Legal Inquiry into the Foundations and Limits of the Liability of Manufacturers of Internet of Things Devices
Published 2025-03-01“…The study highlights the necessity of investment in IoT technologies due to their significant societal benefits, such as improvements in healthcare, resource management, and transportation. To maximize these benefits, there must be concerted efforts from both governmental and private sectors to provide financial support and incentives for research and development. …”
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1691
Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat
Published 2025-05-01“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
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1692
Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Published 2024-12-01“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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1693
Research note: Harnessing the potential of chicken blastodermal cells as a new frontier in poultry science and biotechnology – Establishment of embryonic stem cells and their diffe...
Published 2025-02-01“…Further research exploring the functional attributes of B-ESC-derived SC-LCs is required to elucidate their therapeutic potential in nerve reconstruction/repair.…”
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1694
Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry
Published 2025-05-01“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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1695
Induced Acidic chitinase Expression and Scab-Resistant in Wheat Under Field Condition
Published 2012-09-01Get full text
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1696
Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates
Published 2025-05-01“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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1697
Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases
Published 2015-11-01“…We used a structurally consistent model on kinase‐docking motif interactions to facilitate the discovery of short functional sites in the structurally flexible and functionally under‐explored part of the human proteome and applied experimental tools specifically tailored to detect low‐affinity protein–protein interactions for their validation in vitro and in cell‐based assays. …”
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1698
Faunistic analysis of insects of Deva Vatala National Park and agroecosystem of Gujrat Pakistan
Published 2023-01-01“… Insect biodiversity drives ecological functioning and provides ecosystem services in different landscapes. …”
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1699
Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§
Published 2025-01-01“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
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1700
The high-quality telomere-to-telomere genome assembly of the earthworm (Amynthas aspergillum)
Published 2025-06-01Get full text
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